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Latest company new about Choose trometamol manufacturers from four aspects
2020/12/03

Choose trometamol manufacturers from four aspects

Tris(hydroxymethyl)aminomethane is not only a common biological buffer, but also can be used to prepare related products. Such as bis Tris, Tricine, TES, Taps, etc. These are buffers often used in biochemical experiments and molecular biology experiments. Although its structure is not complex, there are not many domestic manufacturers that can really do Tris well. How do we choose Tris base manufacturers? Let's analyze it through several points.   1. Whether the quality parameters meet the requirements   High quality biological buffer Tris must have the following characteristics: pKa value between 6 ~ 8; good solubility in water system   It has little solubility in organic solvents; it has less permeability to biofilms and is less affected by concentration, temperature and ions in medium, and can form soluble complex with cations; it has excellent stability in dry or solution state, and can resist enzymatic or non enzymatic degradation; it has very small absorption value to visible light and ultraviolet light.     2. Is the stock sufficient   A lot of customer consultation volume is above ton level, if there is not enough spot as support, on the one hand, there will be a lot of loss   Important customers, because it is difficult to have the willingness to continue the negotiation. On the other hand, if an order needs to take a long time to reach the customer's hands if it takes a long time for an order to arrive at the customer's hand under the condition of insufficient goods, the monthly output of Desheng can reach the ton level The goods are very timely, so there is no need to worry about it.     3. is the after-sales service guaranteed   Whether we buy diagnostic reagents or any other products, we would rather spend more money than choose a manufacturer with after-sales guarantee   Home. In this way, when we buy products, we will have a sense of steadiness in our hearts. The same is true for Tris, which is more reliable for businesses with service commitment. If they can guarantee that they can return and exchange without worry if they have quality problems, it shows that they are very trustworthy. Even if there are problems in the use process, they will not worry at all.   4. Whether to adopt the optimal scheme to synthesize Trometamol   There are two synthetic methods of Trometamol: direct method and two-step method. However, the yield and cost of Trometamol produced by direct hydrogenation method are lower than those by two-step method. However, the purity of Trometamol produced by direct hydrogenation method is high, which meets the requirements of reference reagent for purity of Trometamol, and the process is stable and reasonable, which is especially suitable for the production of kilogram grade Batch products, the process is simple and reasonable, product pass rate is high.
Latest company new about Characteristics of nsp-sa-nhs acridine ester
2020/12/03

Characteristics of nsp-sa-nhs acridine ester

Nsp-sa-nhs is not only the internal salt of acridine sulfonylhydrazine amine, but also the active ester. Compared with the pure acridine ester, nsp-sa-nhs has better hydrolysis resistance and better stability when the pH value is less than 4.8.   Appearance   The appearance of nsp-sa-nhs is golden yellow powder, which may be in the form of yellow solid in the frozen state. However, after thawing, it is a loose powder with a very fine texture. Therefore, it is necessary to be careful when loading and unloading to avoid waste caused by spilling.   Packing   Chemiluminescence reagents are usually stored in opaque bottles, and nsp-sa-nhs is no exception. Brown bottles are used, including 10mg and 50mg, of course, 1g large package is also available. Product packaging   Price   Nsp-sa-nhs is relatively moderate among six acridine esters with different groups, and the price will be determined according to the amount of customers. The reason is that small amount of sub packaging will cause the loss of the product itself. In fact, the price fluctuation is still relatively large, 200-60 yuan / mg. Of course, if it's a dealer, the price will be more expensive.   Preservation   Nsp-sa-nhs is the same as other acridine esters. It is sealed and protected from light, stored at 2-8 ℃ for one year, and can be stored for a longer time at - 20 ℃. Moreover, the photoquantum yield of nsp-sa-nhs and protein conjugates does not decrease when stored at room temperature for 4 weeks. This is also a major feature of nsp-sa-nhs.   Because the essence of the antibody is protein, it contains amino groups, which can directly react with NSP-SA-NHS and couple.   Cas199293-83-9, c32h31n3o10s2, molecular weight 681.7, is commonly used in chemiluminescence labeling, immunoluminescence, etc. The purity is higher than 98% according to different manufacturers. This acridine salt and nsp-dmae-nhs are the two most commonly used acridine ester series.
Latest company new about Principle and function of different additives for blood collection
2020/12/02

Principle and function of different additives for blood collection

The vacuum blood collector consists of three parts: vacuum blood collection vessel, blood collection needle (including straight needle and scalp blood collection needle) and needle holder. The vacuum blood collection vessel is the main component, which is mainly used for blood collection and preservation. A certain amount of negative pressure is preset in the production process. When the blood collection needle enters the blood vessel, due to the negative pressure effect in the blood collection vessel, the blood automatically flows into the blood collection vessel; at the same time, various additives are preset in the blood collection vessel, which can fully meet the clinical multiple comprehensive blood detection, safety, sealing, sealing and sealing Convenient transportation.   Vacuum blood collection and additives   Vacuum blood collection is generally divided into the following categories:   1. Dry empty tube without additives: the inner wall of the blood collection vessel is evenly coated with the agent (silicone oil) to prevent wall hanging. It makes use of the principle of blood natural coagulation to coagulate the blood. After the serum is naturally precipitated, it is centrifuged. It is mainly used for serum biochemistry (liver function, kidney function, myocardial enzyme, amylase, etc.), electrolyte (serum potassium, sodium, chlorine, calcium, phosphorus, etc.), thyroid function, drug detection, AIDS detection, tumor markers, serum immunology.   2. Coagulant tube: the inner wall of the blood collection vessel is evenly coated with silicone oil to prevent wall hanging, and Desheng coagulant is added at the same time. The coagulant can activate the fibrin, make the soluble fibrin into the insoluble fibrin polymer, and then form the stable fibrin clot. It is generally used in emergency biochemistry.   3. Blood collection vessel containing separation gel and coagulant: the wall of the tube is silicified and coated with coagulant, which can accelerate the blood coagulation and shorten the test time. The separation gel is added in the tube, which has a good affinity with pet tube, and indeed plays an isolation role. Generally, even on the ordinary centrifuge, Desheng serum separation gel can completely separate the liquid components (serum) and solid components (blood cells) in the blood and accumulate in the test tube to form a barrier. After centrifugation, the serum does not produce oil droplets, so it will not block the machine. It is mainly used for serum biochemistry (liver function, kidney function, myocardial enzyme, amylase, etc.), electrolyte (serum potassium, sodium, chlorine, calcium, phosphorus, etc.), thyroid function, drug detection, AIDS detection, tumor markers, serum immunology.   4. Blood collection vessel with anticoagulant in the tube:   1) Blood collection vessels containing heparin sodium or heparin lithium: heparin is a kind of mucopolysaccharide containing sulfate group, with strong negative charge, which can strengthen the inactivation of serine protease by antithrombin III, thus preventing the formation of thrombin and preventing platelet aggregation. Heparin tube is generally used for the detection of emergency biochemistry and hemorheology, which is the best choice for electrolyte detection. It can't be used to count and classify white blood cells, because heparin can cause leukocyte aggregation.     2) EDTA is a kind of amino polycarboxylic acid, which can effectively chelate calcium ions in blood. Chelated calcium will remove calcium from the reaction point, and will prevent and terminate the endogenous or exogenous coagulation process, thus preventing blood coagulation. Compared with other anticoagulants, it can agglutinate blood cells and blood cells Therefore, Desheng EDTA salts (2k, 3k, 2Na) are usually used as anticoagulants. It can not be used for coagulation, trace elements and PCR.   3) Blood collection vessels containing sodium citrate anticoagulant: sodium citrate plays an anticoagulant effect by acting on calcium ion chelation in blood samples, which is recommended by National Committee for clinical laboratory standardization (NCCLS) as 3.2% or 3.8%, and the ratio of anticoagulant to blood is 1:9, which is mainly used in fibrinolysis system (prothrombin time, thrombin time, activated partial thrombin time, fibrinogen). When taking blood, pay attention to take enough blood volume to ensure the accuracy of the test results. Immediately reverse and mix the blood 5-8 times.   4) The tube contains potassium oxalate / sodium fluoride (1 part of sodium fluoride and 3 parts of potassium oxalate): sodium fluoride is a weak anticoagulant, which can prevent the degradation of blood glucose and is an excellent preservative for blood glucose detection. Attention should be paid to slow inversion and mixing when using. It can't be used to detect urea, alkaline phosphatase and amylase.
Latest company new about Components of blood coagulant
2020/11/16

Components of blood coagulant

Desheng Technology is a new technology enterprise specializing in the research and development, production and sales of blood collection tube additives. It has 15 years of experience in the production of blood collection tube additives. The main components of Desheng's blood coagulant are composed of thrombin, alcohol, silica powder, emulsifier, surfactant, etc., which are suspended liquids.     Serum is one of the main specimens tested in clinical biochemical and immunological tests. At present, the methods of obtaining serum samples in medical institutions are mainly obtained by centrifugation after collecting venous blood after the blood is completely coagulated. Under normal circumstances, it takes more than 60 minutes for an isolated blood sample to completely coagulate, or even not coagulate, which is difficult to meet the needs of rapid laboratory testing.   Under normal circumstances, it takes a long time for the collected blood sample to coagulate naturally at room temperature (2-35℃). Generally, it takes more than 60 minutes for glass tubes and more than 90 minutes for plastic tubes. Since the clinical needs laboratory to provide rapid and accurate laboratory biochemical, immunological and other testing indicators, if the collected blood samples are not processed, it is difficult to meet the clinical needs in time, especially for emergency patients, it is necessary to obtain fast and accurate test results. . The traditional method of promoting blood coagulation is mainly to add kaolin and cephalin to blood samples after collection that can promote blood coagulation. However, with the advancement of clinical laboratory testing methods, some automated and intelligent biochemical and immunological Testing instruments are constantly updated and used for clinical testing and analysis. While the sensitivity and accuracy of these automatic analysis instruments continue to improve, the requirements for specimens are also increasing.   Procoagulant principle of blood coagulant: Activate part of the coagulation factors in plasma and platelets, promote the formation of thromboplastin and fibrin clots, accelerate the contraction of blood clots, and achieve the purpose of rapid serum separation.   Usage and dosage of coagulant: The accelerator can be sprayed by machine or added manually. In the process of adding, it must be stirred continuously to keep the suspension uniform and fully ensure the consistent addition of various active ingredients.   2. Mechanical stirring, electromagnetic stirring, pneumatic stirring, etc. can be used to keep the suspension uniform, and the stirring speed can be adjusted according to actual conditions. 3. After the addition is complete, the coagulant needs to be dried (not needed for non-organic solvent coagulant). The hot air drying temperature can be 40-80℃, and the time is 7-120S; the drying temperature in the drying oven or drying room is about 40C, and the time is subject to thorough drying.   4. Add 20-30ul blood coagulant, it can quickly coagulate 2-5ml blood at 20-25℃. When the ambient temperature is lower than 20°C, or the blood volume is more than 5ml, the amount of coagulant added should be appropriately increased. If irradiation sterilization is required, it is recommended to increase the additive dosage of coagulant by about 20%.   Blood coagulant accelerates the speed of blood coagulation and provides convenient conditions for testing. Desheng is one of the few manufacturers that produces a full set of additives for blood collection tubes. The additives produced include heparin sodium/lithium, EDTA dipotassium/tripotassium, coagulant and sodium citrate, potassium oxalate, separation gel, etc., which are purchased for customers Provided convenience.
Latest company new about Luminol chemiluminescence system without hydrogen peroxide
2020/11/16

Luminol chemiluminescence system without hydrogen peroxide

Luminol is one of the most commonly used chemiluminescence reagents. It can react with a variety of oxidants and has a high luminescence quantum yield and good water solubility. Luminol chemiluminescence system is widely used in many fields such as chemistry, pharmacy, environmental science, food science and clinical medicine. In luminol chemiluminescence system, the most commonly used oxidant is hydrogen peroxide, but hydrogen peroxide is unstable. The chemiluminescence reaction with luminol is slow and the luminescence intensity is low.     To solve this problem, researchers have developed some novel and efficient luminol chemiluminescence systems without hydrogen peroxide.   Researchers such as Xu Baoguo, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, mixed luminol, thiourea dioxide and a solvent to prepare a luminol-thiourea dioxide chemiluminescence system, in which thiourea dioxide and luminol can be produced by reaction Chemiluminescence, thiourea dioxide has good thermal stability, is safe and non-toxic, has no pollution during production and use, has a fast chemiluminescence reaction with luminol, and has high luminous intensity. Compared with the luminol-hydrogen peroxide chemiluminescence system, the maximum luminescence intensity of the luminol-thiourea dioxide chemiluminescence system is increased by 20 times.   Liu Wei of Shaanxi Normal University and others used Co Fe PBA NAFSs aqueous solution, luminol working fluid and paper matrix containing hydrophilic and hydrophobic regions to form a new type of luminol chemiluminescence system, in which Co Fe PBA NAFSs is anisotropic KCoFe self-assembled nanoparticles with cubic frame structure. In this chemiluminescence system, Co-Fe PBA NAFSs can catalyze luminol to produce strong chemiluminescence on the paper substrate. Co-Fe PBA NAFSs act as a catalyst and sensitizer. It can catalyze luminol to produce strong chemiluminescence, and it only takes about 3.7 seconds from the contact of luminol with Co-Fe PBA NAFSs solution to the maximum absorption peak. , The reaction rate is sensitive and fast.   Because of its simple structure and easy synthesis, luminol is widely used as a luminescence reagent for various chemiluminescence analysis and detection. With the development and update of chemical analysis technology, more novel and efficient luminol chemiluminescence systems will emerge in the future. Desheng Technology is a manufacturer of chemiluminescence reagent raw materials, the purity of luminol produced is ≥99%, and the luminous efficiency is high. We can also provide high-quality raw materials such as isoluminol, 6 commonly used types of acridinium esters, and professional after-sales service to allow customers to enjoy one-stop purchase. If you have any questions, please click on the official website to consult our customer service staff.
Latest company new about Application of in vitro diagnostic reagents and magnetic beads and other nanomaterials
2020/11/13

Application of in vitro diagnostic reagents and magnetic beads and other nanomaterials

In chemiluminescence immunoassay experiments, there are two types: plate and tube. Among them, tube chemiluminescence will use magnetic beads as a carrier for adsorbing acridinium ester-labeled antibodies or proteins to facilitate the washing and separation of labeled antibodies. The magnetic beads here are a kind of magnetic biological microspheres, which are nanomaterials. In fact, there are many types of nanomaterials in the in vitro diagnostic reagent industry. The magnetic beads newly developed by the company are different from the original serum separation gel and high molecular polymer materials such as carbomer. Magnetic beads are a kind of more advanced nano materials. Because nanomaterials have unique optical, magnetic, electrical and thermal properties, they can be used to generate different types of detection signals, amplify the intensity of detection signals, and simplify the detection process. Therefore, in vitro diagnostic technology based on nanomaterials has broad application prospects. Nanomaterials can be applied to the detection of nucleic acids, proteins, small molecules, bacteria and viruses. In Vitro Diagnostic Reagents and Magnetic Bead Materials With the rapid development of clinical medicine diagnosis and treatment technology, many traditional and conventional in vitro diagnostic technologies can no longer meet the needs of clinical medicine development. People have higher and higher requirements for the sensitivity, accuracy and specificity of clinical diagnostic analysis. Therefore, nanomaterials Also came into being. In particular, because nanomaterials have a much higher specific surface area than macroscopic materials, they can provide a lot of space to modify different molecules on their surfaces, making them play an important role in applications such as bioanalysis and biosensors. Using these surface-modified nanomaterials with different molecules can selectively detect small molecules, nucleic acids, proteins and microorganisms. There are many different types of nanomaterials, such as semiconductor quantum dots, gold nanoparticles, and magnetic nanoparticles. Among them, magnetic beads are a kind of magnetic nanoparticles, which are widely used in the field of in vitro diagnostic reagents. Nanomaterials can be used for the detection of nucleic acids and antibody proteins in chemiluminescence immunity according to different types; some can be used for enzyme-linked immunosorbent assay (ELISA) immunoassays and DNA microarray detection, etc.; others are used for tumor cell detection and bacteria Detection, virus detection, and tracing of small molecule drugs in living cells, etc., have a very broad application prospects. In the past, acridine esters chemiluminescence reagents mainly relied on imports. Now, due to the good market feedback of the acridine esters developed by Desheng, the magnetic bead materials developed are mainly used for chemiluminescence experiments. Other in vitro diagnostics will be considered later. Application in experiment.
Latest company new about It is important to pay attention to these issues when Use Carbomer gels
2020/11/12

It is important to pay attention to these issues when Use Carbomer gels

Carbomer is a white, loose powder with strong hygroscopicity and acidity. It is soluble in water, glycerin, and ethanol. It has the characteristics of a colloidal solution. The usual concentration is 0.1% to 3%. Due to the low viscosity, when the alkali is neutralized, the viscosity gradually rises as the macromolecules gradually dissolve, forming a clear solution when the mass fraction is low, and a translucent gel when the mass fraction is large. Carbomer not only It is widely used in daily chemicals. It can also be used as a promising new pharmaceutical excipient. The following introduces some problems that should be paid attention to when using carbomer to make gels.   Carbomer model selection   According to the different uses of the prepared gel, choose different types of CP. CP934 has the strongest adhesion and is more suitable for cavity administration, such as commonly used nasal bioadhesives, vaginal bioadhesives, rectal bioadhesives, oral Containing or oral bioadhesives, etc. CP940 has strong adhesion to the skin surface and good spreadability, which can prolong the residence time of the drug on the skin surface and increase the effect of the drug. It is widely used in skin diseases and can absorb tissue exudate, which is beneficial to the exclusion of secretions. Suitable for treatment of seborrheic skin diseases. CP1342 has strong ion resistance, which is more suitable in the presence of electrolyte.   Carbomer quality score selection   According to the different viscosity of the required gel, generally choose the mass fraction of CP from 0.5% to 3%. When formulating skin care products, the final mass fraction of CP should be controlled to be less than or equal to 0.8%. When it is greater than 0.8%, it is easy to form a film and the skin feels bad. In order to achieve the desired consistency, CP can also be used in combination with carmellose, sodium alginate, polyethylene glycol, polyvinylpyrrolidone, etc. to achieve a synergistic thickening effect.   Choice of pH regulator   In order to make CP form a more stable gel, its pH needs to be adjusted from 5 to 11. The CP neutralizer can be sodium hydroxide, potassium hydroxide, potassium bicarbonate, borax and triethanolamine in polar systems, and laurylamine and amine stearate can be used in non-polar systems.   Choice of moisturizer   Since the gel will lose water during storage, it will dry and harden, forming a dry micelle which is not easy to spread. It is necessary to add a moisturizer to maintain the stability of the dosage form and prevent the skin from drying out. Commonly used humectants include polyols such as glycerin and propylene glycol.   Selection of preservatives   Carbomer itself has no nutrition and does not support the growth of bacteria and molds, but it cannot prevent the growth of bacteria and molds using the nutrients present in the gel system, so different preservatives should be selected according to the situation, such as sodium benzoate and p-hydroxybenzene Formate (parabens) and ethanol, etc. Preservatives can also be combined to reduce dosage and achieve synergistic antibacterial effects.   As a professional carbomer manufacturer, Desheng can provide two models of carbomer 940, carbomer 980, high-quality products and services, and higher cost performance than other manufacturers. Desheng has always been favored by customers. This is definitely the driving force for Desheng to move forward. In order to thank new and old customers, we are now launching = a year-end promotional event, the price is as low as 100 yuan/kg, and the opportunity is not to be missed. Please come to consult and order!
Latest company new about HEPES handling and storage tips you must know
2020/11/07

HEPES handling and storage tips you must know

  The full chemical name of Hepes free acid (CAS number: 7365-45-9) is N-(2-hydroxyethyl)-piperazine ethane sulfonic acid (hereinafter referred to as "HEPES") is a zwitterionic biological buffer. It has physical properties including a white powdery appearance at room temperature and its excellent water solubility. 40 grams of HEPES can be completely dissolved in 100 ml of pure water at 20°C. Therefore, it is very easy to use and only needs to be dissolved in water. The scope of application is relatively wide, usually using its pH value for adjustment, cosmetics, cell culture, electrophoresis buffer, etc. HEPES handling and storage recommendations   HEPES powder is resistant to high temperatures and has a melting point of up to 200°C, so it will not be degraded by autoclaving. According to relevant literature, if the HEPES water solution is exposed to ambient light for three hours, cytotoxic hydrogen peroxide (H 2 O 2) will be produced. Therefore, it should be noted that the HEPES water solution must be kept away from light to avoid affecting the experimental results.   Why choose HEPES   As a professional manufacturer of biological buffers, Desheng provides high-quality HEPES according to your application. We also provide a variety of packaging options, and some indicators can be customized according to your needs. Desheng has a professional R&D team, which is very different from a company that only sells or produces. Desheng is based on research and development, and it is our requirement to produce high-quality products.   Desheng HEPES packaging and storage   The conventional HEPES package of Desheng is a cardboard drum of 25kg, lined with a plastic bag, the white powder is packed in the belt, and the tie is tight. When placed, it is generally placed in a dry room and cannot be exposed to direct sunlight for a long time. Standing inventory, the supply is relatively stable. It is best to store at room temperature 2-8℃.   In the fierce market competition, Hubei Xindesheng always adheres to the concept of "quality first, technology leading", strictly controls every batch of goods sold, from the purchase of raw materials to the control of production processes, to product packaging, logistics transportation, and after-sales service, all supervised by professional personnel. So far, in addition to exporting Hepes buffer, Desheng also has dozens of biological buffers for sale. If you are interested, please click on the official website to learn more details!  
Latest company new about Carbomer year-end promotion price CNY 100/kg
2020/11/06

Carbomer year-end promotion price CNY 100/kg

I believe that the term carbomer is no longer unfamiliar to everyone. It is a polyacrylic acid cross-linked polymer, which is mainly used for the thickening of daily chemical products. It can achieve the effect at very low concentration. Carbomer is usually used to increase the viscosity of cosmetics such as shampoo, shower gel, detergent, including some creams, and most daily chemical products contain this ingredient.   This buddy has a big fire in 2020, the reason is very simple, it is an important ingredient of daily chemical products, but because of its unique "personality" was recruited for use in hand sanitizer. The arrival of the new crown demon in 2020 makes everyone be cautious and pay attention to health and disinfection. Otherwise, they will be wiped out by the new crown demon if they are not careful. This makes disposable hand sanitizers containing carbomer have been favored by everyone. During this period, no-wash disinfectant hand sanitizers in major shopping malls were even sold out.   In such a hot situation, many people are guilty of carbomer. In the period when money is out of stock, many manufacturers have lost their conscience with other products posing as carbomer and selling them at high prices. Many customers are deceived for these reasons. The so-called ten years of being bitten by a snake are afraid of well ropes. They can't believe it when they see the price of carbomer at 100 yuan/kg. The promotion price of 100 yuan/kg is real!   Although Desheng already has a number of stable customers in the international market, it hopes to expand its market share. This discount is also Desheng giving customers more benefits. The preferential price period is one month, from October 25, 2020 to November 25, 2020. Don't miss it when time is limited. Speaking of this, there will definitely be people who question whether the price is so cheap or the quality is not good. The old saying goes that you get what you pay for. This time, Desheng broke this old saying and achieved price concessions and quality assurance. Desheng was established in 2005 and specializes in polyacrylic acid material products. So far, it has developed three generations of serum separation gels for different purposes and carbomer products for different purposes. Secondly, Desheng is the manufacturer of Carbomer, so all the indicators of its products meet the requirements of international brands, and it can also support individual index customization. Compared with other products, it can be found that Desun Carbomer powder is whiter and has better bulkiness, and the dissolved gel has higher transparency than other products. In addition, Desheng has perfect after-sales service, Desheng promises that any quality problems can be returned and replaced. You can apply for a free sample trial, so you can try it first and then buy it.   This event is aimed at Carbomer 940 and 980, which can be purchased in small quantities or signed annual contracts to enjoy ultra-low discounts. The good quality of Desun Carbomer products is supported by one-stop procurement service. Whether it is direct ordering by customers or procurement by traders, choosing Desun is the right choice.
Latest company new about Two types of Virus transport media
2020/11/05

Two types of Virus transport media

2020 has entered the last quarter, and the research and development of the new crown vaccine is in full swing around the world, but before the large-scale vaccination of the vaccine, the nucleic acid detection of the virus is still a vital part of the anti-epidemic process. Therefore, Virus transport media and virus sampling tubes are still in huge demand. Which one is better, inactivated or activated?   According to different detection conditions and requirements, the Virus transport media is divided into two types: inactivated and activated. Among them, the inactivated type of Virus transport media contains high concentration of lysis salt, which can quickly lyse and inactivate the virus contained in the sample, but retain the viral nucleic acid; activated type will not inactivate the virus, but can be more completely retained The protein coat and nucleic acid of the virus. Therefore, both types of virus preservation solutions can be used for nucleic acid detection.   Virus transport media for nucleic acid detection After the first round of national nucleic acid testing in China, it can be said that we have the world's leading level in terms of the efficiency and accuracy of viral nucleic acid testing. It also has mature technology and rich experience in the pre-processing of nucleic acid detection such as Virus transport media and virus sampling. So based on the experience of this period of time, is there a better choice among the two Virus transport media ?   As far as the current situation is concerned, it should be that two types of Virus transport media will co-exist, each of which has its own advantages. The inactivated virus preservation solution will inactivate the virus, so that it will not cause secondary infection, but this does not mean that the activated virus is likely to cause infection, because the mature technology, rich experience and strict control can completely eliminate The actual result of the secondary infection in the sampling process was that there was no virus transmission caused by the virus sampling tube.   Similarly, the virus retained by the activated Virus transport media is more complete and the detection is more accurate. It does not mean that the detection of the inactivated type is not accurate enough. In fact, through the improvement of detection technology and sophisticated instruments, the detection result is completely accurate and the detection is more accurate. The viable storage solution has lysed the virus protein, and the nucleic acid can be directly extracted for PCR experiment in the future.   Therefore, activated and inactivated Virus transport media should coexist for a long time. For manufacturers, only one type of preservation solution is more conducive to management and cost control than two types. Desheng still provides inactivated and activated versions. There are two types of active types, which are more convenient for the application enterprises to choose according to their requirements.
Latest company new about Confessions of Capo Elf
2020/11/04

Confessions of Capo Elf

My name is carbomer 980, and there is a number 940 that is my brother, the title of Kabo elf, after all, the status is noble, although many people do not know it. I admit that although I am a fat white man, I don't want to be black. The beauty and health of humans depend on us.   I pride myself on my noble status. This is not completely unfounded. We are all high-molecular polymers with a relative molecular weight of 40,000 to 100,000 or even higher, which is not found in nature. Although I am a fat man in appearance, it is just puffiness. I can say that it is a light body and a body weight of only one-fifth of water, which means that a cube is only 200 kilograms. Of course, because it is relatively fluffy, the proportion will increase significantly under heavy pressure, and it can increase by five or six times, and that is a veritable 200 catty fat man.   Regardless of appearance, my capo elf's skills are still very powerful. Although not many people know me, I participate in the cosmetics, creams, lotions, shampoos and other products that people use every day, as well as some medicines. For example, carbomer eye drops and carbomer medicinal gel also contain me, and we are also well-known in the pharmacopoeia.   In this year when the new crown virus is raging around the world, I, Comrade Kabo, is also struggling on the front line of the fight against the epidemic. One of the important ingredients in hand sanitizers is carbomer. We have super water absorption performance, thickening performance, gel performance, etc., not only in water, but also in alcohol or other alcohols, Carbo also has good gel suspension performance. We only need 0.5%-2.0% of the usage amount to form a gel, no matter whether it is the amount of water or the amount of alcohol.   Having said that, Comrade I Capo is definitely a good citizen who practices the core values ​​of socialism and abides by the law. Sadly, he has not been wronged! For example, some people say: Carbo is extracted from pure natural plants and contains Chinese herbal medicines. This is too much. It is said that it is a polymer, a synthetic material! Others say that Carbo can beautify skin, whiten and sunscreen. This is not right. Like water, whether it is used in skin care products or as a medicinal adjuvant, it is just a carrier and a medium. Others say that I can cause cancer. This is even worse. The carcinogen is benzene. Because it is made of petrochemical raw materials, petroleum contains benzene and needs to be removed. The pharmacopoeia requires benzene content and heavy metal content. Don't buy fake and shoddy products.   My self-introduction comes to an end here. The new crown virus is unrelenting and trying to make a comeback. I hope everyone will not take it lightly, gather less and eat more vegetables, and products that will not get sick are sold!
Latest company new about TRIS buffer formulation (reference)
2020/11/03

TRIS buffer formulation (reference)

10 mM Tris, 0.1% sodium azide, pH 8.0±0.1   CEA and PSA dilution buffer, specially designed for the preparation of certain CEA, PSA and non-complex PSA. But when other buffer salts are not needed, it is a suitable Tris buffer.   ingredient   Tris base: 1.210 g/L Sodium azide: 1.0 g/L 5M HCl: as required 5M NaOH: as required Distilled water (dH2O)   Instructions for use   1. Use cold dH2O to dissolve sodium trichloride and sodium azide about 90% of the final volume.   2. Add cold dH2O to obtain the final volume.   3. Adjust the pH to 8.0±0.1 with 5M HCl or 5M NaOH as needed. Filter as needed.   10 mM Tris, 150 mM sodium chloride, 0.1% sodium azide, pH 8.0±0.1   Ferritin dilution buffer is specially designed for liver ferritin and spleen ferritin. It is suitable for Tris buffer used when other buffer salts are needed.   ingredient   Tris HCl: 1.296 g / L   Tris base: 0.215 g/L   Sodium chloride: 8.766 g/L   Sodium azide: 1.0 g/L   5M HCl: as required   5M NaOH: as required   Distilled water (dH2O)   Instructions for use   1. Use cold dH2O to dissolve Tris-HCl, Tris-Base, sodium chloride and sodium azide about 90% of the final volume.   2. Adjust the pH to 8.0±0.1 with 5M HCl or 5M NaOH as needed. To   3. Add cold dH2O to obtain the final volume.   4. Check the pH value and adjust the pH to 8.0±0.1 with 5M HCl or 5M NaOH as needed.   20 mM Tris, 1 mM EDTA, 50% glycerol, pH 8.5±0.1   Myoglobin dilution buffer is specially designed for cardiac myoglobin and skeletal muscle myoglobin. When EDTA and glycerol provide extra stability, it is suitable for Tris buffer.   ingredient   Tris HCl: 1.950 g/L Tris base: 0.920 g/L EDTA, four Sodium: 0.416 g/L Glycerin: 500 ml/L 5M HCl: as required 5M NaOH: as required Distilled water (dH2O)   Instructions for use   1. Dissolve about 45% of the final volume of Tris-HCl, Tris-Base and EDTA with cold dH2O.   2. Adjust the pH to 8.5±0.1 with 5M HCl or 5M NaOH as needed. To   3. Add cold dH2O to obtain about 50% of the volume.   4. Add cold glycerin to obtain final volume, mix well and cool.   5. Check the pH value and adjust the pH to 8.5±0.1 with 5M HCl or 5M NaOH as needed.   20 mM Tris, 150 mM sodium chloride, pH 7.4±0.1   ACT dilution buffer, specially designed for a1 anti-chymotrypsin. This solution is similar to the ferritin dilution buffer, but with a higher concentration of Tris and a slightly lower pH. To   ingredient   Tris base: 2.420 g/L   Sodium chloride: 8.766 g/L   5M HCl: as required   5M NaOH: as required   Distilled water (dH2O)   Instructions for use   1. Dissolve sodium trichloride and sodium chloride with cold dH2O, about 90% of the final volume.   2. Adjust the pH to 7.4±0.1 with 5M HCl as needed.   3. Add cold dH2O to obtain final volume and cool.   4. Check the pH value and adjust the pH to 7.4±0.1 with 5M HCl or 5M NaOH as needed.   5. Use a 0.45 µm filter for filtration.   20 mM Tris, 280 mM sodium chloride, 5 mM calcium chloride, 0.1% sodium azide, pH 8.0±0.1   CRP dilution buffer, specially designed for highly purified C-reactive protein, is suitable for situations that require higher concentrations of Tris, buffer salts and calcium chloride.   ingredient   Tris base: 2.423 g/L Sodium chloride: 16.363 g / L Calcium chloride: 0.735 g/L Sodium azide: 1.0 g/L 5M HCl: about 3 ml / L 5M NaOH: as required Distilled water (dH2O)   Instructions for use   1. Dissolve sodium trichloride and sodium chloride with cold dH2O, about 90% of the final volume. 2. Adjust the pH to 8.0±0.1 with 5M HCl as needed. 3. Add cold dH2O to obtain final volume and cool. 4. Check the pH value, adjust to pH 8.0±0.1 with 5M HCl or 5M NaOH as needed, and then add sodium azide. 5. Add calcium chloride to completely dissolve it. (Important: The pH cannot be adjusted after adding calcium chloride.) 5. Use a 0.2 µm filter for filtration.
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