China Wuhan Desheng Biochemical Technology Co., Ltd Company News

For many people, blood detection are far away from us. Everyone only sees the relevant detection process on TV, but many people certainly do not know that there is a chemiluminescent reagent behind the success of the detection. It is luminous ammonia luminol. The murderer often uses various methods to clean up the scene after the murder. When the scene is processed until the blood can not be found by the naked eye, it is necessary to rely on the luminol reagent to investigate the scene.   In fact, in the early twentieth century, benzidine was a commonly used reagent for detecting blood stains, but because benzidine and its salts are both toxic and carcinogenic substances, their solids and vapors are easy to enter the body through the skin, so this The method is gradually deprecated, and it is now banned in many countries such as China and the United States.   Then there was a comer. In the 1830s, German crime scene experts unintentionally discovered that Lumino would produce fluorescence after contact with blood. Later, Western countries began to study the mechanism. Until now, Lu Mino reagent has become the most widely used star reagent in blood stain survey in various countries.   Even if the blood at the crime scene has been wiped or cleared, forensics can still use Luminol to find their location. In fact, the investigator sprayed the luminol and activator solution in the area to be investigated, and the iron in the blood immediately catalyzed the luminescent reaction of luminol, causing it to produce a blue light. The amount of catalyst required for this reaction is very small, so Luminol can detect traces of blood. The glow lasts about 30 seconds.   Lumino is widely used in criminal investigation, bioengineering, chemical tracing and other fields. It is precisely because of its magical effect that it is sought after by many criminal investigation enthusiasts. The professional manufacturer of chemiluminescent reagents includes not only luminol, but also isoluminol, acridinium ester and other products, welcome to contact us for further consultation~!  

  When it comes to chemiluminescence or acridinium esters, you may think that it is a term that is too professional, far away from your life, even in the university's biochemistry major, it is rarely mentioned.However, if I say immune response, you are probably no stranger. Chemiluminescence immunoassay (chemiluminescence immunoassay, CLIA) started in the early 1980s and rapidly developed in the 1990s, becoming a development after fluorescence immunoassay, radioimmunoassay and enzyme-linked immunoassay Emerging immunodetection technology. It uses the specific reaction of antigen and antibody for detection, and uses isotopes, enzymes, chemiluminescent substances to amplify and display the detection signal, and is often used to detect trace substances such as proteins and hormones. In connection with actual life, that is, you go to the hospital to check the thyroid hormones, the diagnostic methods that sex hormones will use.     Immunological diagnosis occupies a very important position in clinical diagnosis. Common immunological techniques include radioimmunity, enzyme-linked immunity, chemiluminescence, electrochemiluminescence, and nanomagnetic particle chemiluminescence. Chemiluminescence immunoassay technology mainly has the advantages of high sensitivity, strong specificity, good reagent stability and long validity, wide detection linear range, simple operation, stable and fast method, many test items (as shown below), and high degree of automation. It has become the mainstream method of immunoassay technology and is widely used in various fields of clinical testing. Acridinium ester labeled antibody detection IgG     The acridinium ester mentioned above is a type of chemical substance that can be used as a chemiluminescent marker. In alkaline H2O2 solution, when the molecule of the acridinium ester is attacked by hydrogen peroxide ions, the substituent on the acridinium ring can It forms unstable dioxyethane with C-9 and H2O2 (hydrogen peroxide) on the acridinium ring, which decomposes into CO2 and electronically excited N-methylacridone. There are a total of 7 different groups of acridinium ester products, 1. AE-NHS (traditional acridinium ester); 2. DMAE-NHS; 3. Me-DMAE-NHS; 4. NSP-DMAE-NHS; 5 . NSP-SA-NHS; 6. NSP-SA; 7. NSP-SA-ADH.     These acridinium esters produced by Desheng have the characteristics of high product purity and small batch-to-batch difference. They also provide other immune reagents for matching use, provide a full set of technical services and technical support, please contact us for inquiries! Website: www.vacutaineradditives.com, Phone: +86-711-3702650.  

Acridinium ester, a type of chemical substance that can be used as a chemiluminescent marker, with a yellow powder appearance. In alkaline H2O2 solution, the molecules of acridinium ester are affected by hydrogen peroxide ions. The ring C-9 and hydrogen peroxide form unstable dioxane, which decomposes into CO2 and electron-excited N-methylacridone.   Acridinium ester reaction process The acridinium ester chemiluminescence process reacts quickly and has a low background, and can emit light in the presence of sodium hydroxide and hydrogen peroxide. During the oxidation reaction, the conjugate is decomposed without affecting the luminescence of the free acridinium ester; in addition, the acridinium ester chemiluminescent reagent has good stability and is easy to store.   The difference between acridinium ester and other mainstream chemiluminescence reagent Type Marking, reaction system Main advantages Main disadvantages     Chemiluminescence Enzymatic Peroxidase, luminol, oxidant, enhancer, etc. Simple measurement method (rate method), low cost, high sensitivity The working curve drifts with time and the low-end slope shifts nonlinearly Spiral adamantane epoxide, alkaline phosphatase Simple measurement method (rate method), high sensitivity Non-enzymatic Acridinium ester, hydrogen peroxide high sensitivity Short luminescence time, complicated measurement method (integral method), in-situ injection (In Situ Injector), high instrument cost and maintenance cost, and high reagent cost Electrochemiluminescence Pulsed electric field excitation of ruthenium (Ru) complex High sensitivity and stable reagents Complex measurement methods (pulse excitation, intermittent measurement, flow cell), high instrument cost and maintenance costs, similar elements in the environment and samples can lead to background interference   Desheng Technology develops and produces 6 acridinium ester products with different groups. Although the substituents are different, they have the same acridinium ring. Whether they are acridinium ester or acridinium hydrazide, their luminescence principles are the same. The acridinium ester developed and produced by Desheng Technology belongs to laboratory production, and the quality control is stricter. Desheng has a professional technical R&D team, an excellent logistics partner, professional packaging services, and more than ten years of production R & D experience. It has the ability to provide end users with a strong problem-solving ability. Looking forward to you further consultation. Please contact tel:0711-3702650 for details.  

    The chromogenic substrate TOPS, the full name of N-ethyl-N- (3-sulfopropyl) -3-methylaniline sodium salt, is similar to TOOS, the difference in molecular structure is that the sulfopropyl group on the single atom connected to the benzene ring With a hydroxyl group, the stability is slightly stronger, and all have the characteristics of high water solubility and high detection sensitivity.   Like TOOS, TOPS can also be used for uric acid detection in kidney function kits. The chromogen used by uric acid detection kits of different companies is slightly different (the chromogenic substrate ESPMT used by some companies refers to TOPS). In addition, TOPS is also commonly used for liver function series free fatty acid detection and renal function series creatinine detection. The following is an example of the principle of uric acid detection.        During clinical testing, first collect venous blood from the test subject. The subject should be fasting for 12 hours. It is best not to drink alcohol in the morning and 12 hours. The blood collection tube should be disinfected. The blood sample is not hemolytic. The detection of uric acid is to first catalyze the complete oxidation of uric acid with oxygen and water to allantoin, carbon dioxide and hydrogen peroxide H2O2. H2O2 reacts with TOPS and 4-AAP under the catalysis of POD. TOPS is oxidized into a chromogenic product, and the absorbance is measured with a spectrophotometer. The intensity of the absorbance is proportional to the uric acid content, so that uric acid analysis is performed. This is a typical biochemical detection method using two-step enzymatic reaction to measure.           Desheng Technology has more than ten years of experience in R&D, production and sales in the field of diagnostic raw materials, especially in the development and improvement of new Trinder's reagents in the aniline sodium salt derivative series. It performs functional groups on the basis of traditional chromogenic substrates. Replacement of the increase and decrease, continue to make optimization and performance improvement for the needs of clinical testing!

     The full name of TOPS (CAS No.:40567-80-4) is N-ethyl-N-(3-sulfopropyl) -3-methylaniline sodium salt, which is a white to light brown powder, also a member of the new Trinder's reagent family. Maybe you think the name sounds humongous, and it is a vocabulary that a fully professional pharmacist only understands. It is even more difficult to relate to your life. If you think so, you are wrong. You may not have heard of this name, but I think most of you or people around you have done biochemical tests in the hospital, that is, liver function, kidney function, uric acid, cholesterol and other tests. Most of these tests are carried out by automatic biochemical analyzers, uric acid analyzers, etc. in conjunction with the corresponding kits. And one of the core raw materials in these kits is the TOPS we talk about today.        In humans and primates, uric acid is the final product of purine metabolism. It is produced by the oxidation of xanthine and hypoxanthine by xanthine oxidase and is excreted in the urine. High serum uric acid and hyperuricemia are associated with insulin resistance, cardiovascular disease and gout. The mechanism leading to hyperuricemia is usually increased uric acid production or decreased urine excretion. Increased serum uric acid may be a sign of kidney disease, so the early diagnosis of kidney disease can be indirectly through the test of uric acid.   TOPS Product description Chinses name N-ethyl-N- (3-sulfopropyl) -3-methylaniline sodium salt English name Sodium 3-(N-ethyl-3-methylanilino)propanesulfonate CAS No. 40567-80-4 Hs code 2922199090 Molecular formula C12H18NNaO3S, H2O Molecular weight 297.34 Appearance White or light brown powder Storage condition 0-5℃，away from light and moisture Transport condition Room temperature（20-25℃） Maximum absorption wavelength 550 nm Oxidation reaction Applacation This product is used for the colorimetric determination of uric acid and cholesterol. It has the characteristics of good water solubility, high sensitivity and strong stability. Cholesterol colorimetric determination; water-soluble reagent, used for catalase photometric determination.         In the presence of hydrogen peroxide and peroxidase, TOPS reagent is formed during the oxidative coupling reaction with 4-aminoantipyrine (4-AA) or 3-methylbenzothiazolone hydrazone (MBTH) Very stable purple or blue dye. The substrate is enzymatically oxidized by its oxidase to produce hydrogen peroxide. The concentration of hydrogen peroxide corresponds to the substrate concentration. Therefore, the amount of the substrate can be determined by the color development of the oxidative coupling reaction to obtain a relatively accurate test result of the concentration of the analyte. TOPS produced by Desheng has obtained the quality certification of more than 100 manufacturers nationwide. Because of its color rendering sensitivity, color stability and anti-interference, as well as the accuracy and precision of specific measurement items, it has been well received by customers. You are welcome to inquire, the company will provide you with quality products and excellent services, so that your products rank among the industry's leading level! Company website: https://www.vacutaineradditives.com, Phone No.: +86-711-3702650.

The full name of the chromogenic substrate MAOS is N-ethyl-N- (2-hydroxy-3-sulfopropyl)-3,5-dimethylaniline sodium salt monohydrate, CAS No. is 82692-97-5. As other new Trinder ’s reagents, it has high water solubility and sensitivity much higher than traditional chromogenic reagents commonly used in some laboratories, so it is widely used in clinical testing and biochemical reagent kits.   First, the biggest feature of MAOS is that the maximum absorption wavelength of its oxidized product is far more than that of ordinary chromogenic reagents. Even in the new Trinder ’s reagent, its product UV absorption wavelength is 630nm, which is quite high. The maximum absorption wavelength of products of many chromogenic reagents is in the visible light region. If testing human blood or other body fluids, due to the complex components in the sample to be tested, the sample itself contains a small amount of components that absorb wavelengths in the visible light region or absorb with chromogenic products.   The wavelengths are close, which will make the detection result high. If you use something like MAOS, the maximum absorption wavelength of the product is in the ultraviolet region and it is relatively high, which will greatly reduce interference. Therefore, it is recommended to use MAOS as a chromogenic substrate for some biochemical testing items that require highly accurate values.   Secondly, the chromogenic reaction of MAOS chromogenic substrate has a wider adaptability to the pH of the reaction system, which greatly improves its adaptability. The reaction of some chromogenic reagents is often performed under acidic conditions, but the biochemical detection usually requires the participation of enzymes. We know that the catalytic effect of enzymes is relatively sensitive to the pH of the reaction environment, and it may not match the chromogenic reagent Inactivation will be greatly restricted in use, and MAOS reagents do not have this problem.   Another point is that the MAOS chromogenic reaction has a larger molar absorption intensity, so its sensitivity is relatively high. It should be noted that MAOS will fade when the detection time is too long, so the MAOS detection needs to be completed in time and cannot be interrupted. In addition, MAOS is also relatively safe. Unlike DAB and other biphenyl chromogenic reagents, although the price is relatively low, it has certain carcinogenicity or mutagenicity.   Desheng Technology has been committed to the development, production and sales of various chromogenic substrates, especially TOOS, MAOS, ADPS, etc. have a good reputation at home and abroad, and have good cooperation with many biochemical kit manufacturers Relationship, and jointly contribute to the field of domestic diagnostic reagents!

As a new Trinder's reagent, MAOS occupies a pivotal position in it. It is a white powder that is easily soluble in water. Chinese name: N-ethyl-N- (2-hydroxy-3-sulfopropyl) -3 , 5-Dimethylaniline sodium salt monohydrate, sensitive to light and humidity, CAS number: 82692-97-5, purity requirement> 99%, molecular structure is shown in the following figure:   Application of MAOS The new Trinder's reagent is a highly water-soluble aniline derivative, which is widely used in diagnostic tests and biochemical tests. It has several advantages over conventional color-generating reagents in the colorimetric determination of hydrogen peroxide activity. The new Trinder's reagent is stable enough to be used in both solutions and test line inspection systems. In the presence of hydrogen peroxide and peroxidase, the new Trinder's reagent during the oxidative coupling reaction with 4-aminoantipyrine (4-AA) or 3-methylbenzothiazole sulfone hydrazone (MBTH), Forms a very stable purple or blue dye.   The molar absorbance of the coupling dye with MBTH is 1.5-2 times higher than that with 4-AA; however, the 4-AA solution is more stable than the MBTH solution. The substrate is enzymatically oxidized by its oxidase to produce hydrogen peroxide. The concentration of hydrogen peroxide corresponds to the substrate concentration. Therefore, the amount of substrate can be determined by the color development of the oxidative coupling reaction. Glucose, alcohol, acyl-CoA and cholesterol can be used to detect those substrates coupled with the new Trinder's reagent and 4-AA. There are 10 new Trinder's reagents, and the use of MAOS members is also very important. For specific substrates, testing different types of new Trinder's reagents is necessary to develop the best detection system.   Product introduction Oxidizing chromogen reagents, high water solubility, stable aniline analogues, a wide pH range for color development and oxidation reactions   Preparation of detection solution-MAOS (other substrate configuration methods are basically the same)   1. Dissolve 20 mg MAOS in 10 ml PBS to prepare a 6.6 mM MAOS solution. (The specific solubility is adjusted as needed)   2. Dissolve 14 mg 4-aminoantipyrine (4-AA) in 10 ml PBS to prepare a 6.6 mM 4-AA solution.   3. Prepare 2 U / ml horseradish peroxidase solution in PBS.   4. Mix equal volumes of each solution to prepare a test solution. Store the test solution in the dark at 4 ℃   Detection steps   1. Prepare a sample solution for the enzymatic oxidation reaction. The pH value of the buffer solution should be 5.5-9.5.   2. Use the same buffer to prepare a standard solution containing a known amount of substrate.   3. Add appropriate units of oxidase to the sample solution, followed by an equal volume of detection solution.   4. Incubate the mixture at room temperature or 37 ° C for 30 minutes to 1 hour.   5. Determine the O.D. value at 555 nm.   6. Prepare a standard curve and determine the substrate concentration in the sample solution     MAOS belongs to one of Desheng Biochemical's key sales varieties. At the same time, TOOS, TOPS, ADOS, ADPS, ALPS, DAOS, HDAOS, MADB and other new Trinder's reagents are available for customers to choose. Desheng always upholds: Honesty first; quality first, technology leading; customer-oriented, symbiosis and win-win; pioneering and innovative, the pursuit of excellence in business philosophy, dedicated to providing our customers with quality products and services, welcome to consult and cooperate!  

TOOS is also called EHSPT (N-ethyl-N- (2-hydroxy-3-sulfopropyl) -3-methylaniline sodium salt), which is a highly water-soluble sodium salt of aniline. It is sensitive when performing Trinder reaction. It is much higher than traditional phenol, aniline, ADA and other color-developing substrates. Clinical biochemical testing is often used in liver function kits, blood glucose metabolism kits, etc.   In the presence of hydrogen peroxide and peroxidase POD, Trinder's reagent forms a very stable orange or red quinone with 4-aminoantipyrine (4-AAP). The molar absorbance of TOOS and MBTH coupling dye is 1.5-2 times higher than that of 4-AA coupling dye; however, 4-AAP solution is more stable than MBTH solution, so Trinder ’s reagent is more used with 4-AAP. When tested with a biochemical kit, the measured indicators such as uric acid, glucose, glycated albumin, and 1,5-anhydroglucitol are equal to the enzymatic oxidation of its oxidase to produce hydrogen peroxide.   The concentration of hydrogen peroxide corresponds to the concentration of the substance to be tested Therefore, the amount of the analyte index can be determined by the color development of the oxidative coupling reaction. Certainly, the indicators of enzyme activity can also be measured, such as the adenosine dehydrogenase detection kit and 5'-nucleotidase detection in the liver function series, which is the reaction of the enzyme to be detected and its corresponding catalytic substance to generate peroxide Hydrogen is then reacted with the generated hydrogen peroxide through the coloring substrate TOOS coupling 4-AAP, and the final coloring product production rate corresponds to the activity of the tested enzyme, thereby achieving the purpose of measuring the index.   The TOOS color development substrate developed by Desheng Technology has the characteristics of high purity, high water solubility, and low interference ion. It is very convenient to use when it is used, and the company also produces Tris buffer used with it for biochemical detection. Wait, the quality and service are well received!

I believe that everyone must have had such experience. When going to the hospital for medical treatment or routine medical examination, sometimes the doctor will ask you to do a blood test and a complete biochemical examination. In fact, the clinical biochemical detection mentioned here refers to studying the biochemical changes under the pathological state on the basis of the normal metabolism of the human body, by analyzing the changes of related metabolites in the body, looking for characteristic markers, establishing corresponding detection methods for disease prevention , Diagnosis, treatment and prognosis to provide biochemical information and decision-making basis.   Furthermore, biochemical diagnosis refers to an in vitro diagnostic method that uses Lamber-Beer's law to measure various biochemical indexes of various inorganic elements, proteins, and non-protein nitrogen and enzymes, sugar, and lipids in vitro through various biochemical reactions. Liver function, kidney function, blood sugar, blood lipids and other inspection items belong to the biochemical diagnosis. Clinical biochemical diagnostic reagents and biochemical analyzers are used in combination, and the relevant technical principles of chemistry, enzymes, immunology, etc. are applied to diagnose clinical biochemical indicators related to the human body. Through the specific reaction between the reagent and the related analyte, a specific optical signal is given, which is recorded by the biochemical analyzer and compared with the calibrator to give the level of the related analyte. Biochemical diagnosis is one of the most commonly used in vitro diagnostic methods at present, and it is also the earliest and most mature IVD subdivision field developed at home and abroad.   Among them, Trinder's reaction is a routine biochemical detection project catalyzed by a specific substrate oxidase. The oxidase catalyzes the substrate to produce hydrogen peroxide (H202). In the presence of phenol and 4-aminoantipyrine, hydrogen peroxide Peroxidase catalyzes the production of quinone compounds and water, which reflects the amount of hydrogen peroxide produced by the coloration of the quinone compounds, and indirectly detects a certain substrate concentration or a certain oxidase activity. Among the new Trinder's reagents, TOOS is the most commonly used because of its high water solubility, high molar absorbance (that is, more sensitive color reaction), color reaction intensity and fading. TOOS produced by Desheng is favored by more than 100 manufacturers because of its crystal morphology, high crystal purity, and pure white crystal color (important for this color reaction). The following are the relevant indicators of TOOS, please refer to it.   Product description TOOS is a new type of high water-soluble aniline derivative, widely used in diagnostic tests and biochemical tests. molecular weight 295.33 Molecular forluma C12H18NNaO4S CAS No. 82692-93-1 purity ≥99.5% SMILES O=S(CC(O)CN(CC)C1=CC=CC(C)=C1)([O-])=O.[Na+] Packaging details 10g/bottle；50g/bottle Transpotation conditions Room temperature（20℃-25℃） Storage conditions powder -20°C 3 years 4°C 2 years solution -80°C 6 months -20°C 1 month   remarks In Vitro: DMSO : ≥ 47 mg/mL (159.14 mM) *"≥"means soluble and does not represent saturation.   As a domestic senior manufacturer specializing in blood test reagents for 19 years, Desheng is committed to providing raw materials to help accurate diagnosis and treatment. Its TOOS products have been evaluated by more than 100 professional manufacturers in the industry and received numerous praises. If you are interested, please call to consult!

Many customers who purchase lithium heparin are facing a problem. They inquire from many lithium heparin manufacturers. In order to reduce procurement costs, they often choose the lower price manufacturer. After receiving the goods, they find that the product quality is not guaranteed at all. Must look at the cost performance. Buying products that do not meet the test requirements at a low price is a waste of manpower, material resources, and financial resources. Wise people know that it is impossible to buy really good products at a low price.   The heparin produced by Desheng Lithium is a very reliable choice. Lithium heparin not only has a variety of potency for its choice, but the price is also worthy of that quality. Really achieve high efficiency and price ratio, high quality and high guarantee. Desheng always believes that quality is the prerequisite for everything. Only good products can be repeatedly purchased by customers.   Some issues that need to be paid attention to when purchasing lithium heparin,   1. In order to ensure adequate blood anticoagulation, the heparin lithium anticoagulant test tube must be reversed and mixed 5-8 times as soon as possible after blood collection, especially when the blood collection temperature is higher than 25 ℃, the blood and lithium heparin must be mixed in time and Otherwise, it may easily lead to blood clotting or local clotting.   2. Lithium heparin anticoagulation is not irreversible anticoagulation, so the test should be completed within 6 hours after the blood collection of the heparin lithium anticoagulation test tube, otherwise it may cause errors in the test results. The dosage of lithium heparin should ensure that the specimen is fully and partially anticoagulated, so that most of the plasma indicators can be repeated within 6 hours, especially sensitive indicators such as AST, ALT, TBIL, DBIL, and GGT.   3. Lithium heparin can be used together with the separation gel. The anticoagulation effect, tube wall siliconization, centrifugal conditions, separation gel quality, etc. will affect the blood separation effect. It is recommended to use with the blood separation gel produced by our company to obtain high-quality plasma specimens. Recommendation for irradiation sterilization after adding to blood collection tube: use γ-ray irradiation, the dose is 8-25kGy. The irradiation dose can be determined by the initial colony number.   The lithium heparin product developed by Desheng has the characteristics of customizable potency. The conventional one is 160IU / mg, but it can be adjusted according to customer needs. 150IU / mg, 170IU / mg, 180IU / mg, the higher the potency, the price It will also change with it. Desheng's lithium heparin product has higher purity than other companies, and the appearance is pure white.   It can be seen directly by the naked eye that there are no foreign substances in other magazines, and the price is also higher than other products. Manufacturers are more favorable, and products are sold all over the country. Desheng is the first choice for purchasing lithium heparin products.    

Heparin is a blood anticoagulant commonly used in vacuum blood collection tube. Heparin anticoagulant is usually its sodium, potassium, lithium, ammonium salts, such as sodium heparin, lithium heparin, etc., among which lithium heparin is the best. The appearance of the finished lithium heparin is white to almost white powder, odorless, soluble in water and hygroscopic. According to the study, there was no significant difference in the results of TP, ASO, UA, ALT, Mg, Cl, TC and CRP between lithium heparin anticoagulant plasma and serum (P > 0.05). There were significant differences in the results of HBD, LDH and TBA between lithium heparin anticoagulant plasma and serum (P < 0.05). Therefore, except for HBD, LDH and TBA, the correlation between lithium heparin anticoagulant plasma and serum is good. Therefore, it is feasible to replace serum with lithium heparin anticoagulant plasma in life detection, which can be used as an important detection method.   [Scope of Application] 1. The product is suitable for blood sample collection and anticoagulation in clinical biochemical examination and emergency biochemical examination, and also for blood sample collection and anticoagulation in some hemorheology projects.   2. Lithium heparin is recommended as an anticoagulant when determining ionic content in blood in clinical tests, because it is least likely to interfere with the determination of other ions.   3. This product is not a drug and cannot be used as an injection. Direct injection into human body and animals is prohibited. [Precautions] Heparin salt test tube must be inverted and mixed 5-8 times as soon as possible after blood collection. Heparin anticoagulation is not irreversible anticoagulation, so the lithium heparin test tube should be completed within 6 hours after blood collection. 3. Heparin may be involved in the metabolism of cellular enzymes and ions, and the amount of heparin additive should ensure adequate anticoagulation of all and local specimens, especially sensitive indicators such as AST, ALT, TBIL, DBIL and GGT.   4. Lithium heparin can be used with separation gel at the same time. Anticoagulation effect, wall silicification, centrifugation conditions, separation gel quality, etc. will affect the blood separation effect. It is suggested to cooperate with the serum separation gel produced by our company.   5. Suggestions on Sterilization: use γ irradiation at a dose of 8-25 kGy.   De Sheng's lithium heparin potency is ≥ 150 IU/mg and anhydrous potency is≥160 IU/mg) are controlled with reference to the standard of sodium heparin API. The lithium heparin aqueous solution can be sealed and stored at 0-4℃ in a sterile state, and should be disposed and used up as soon as possible. Its maximum shelf life should not exceed 7 days,  

[Product name]Virus Transport Media [Packaging specifications]1L/bottle、5L/bottle [Product performance] Non-inactivated type: it does not contain lysate, which can maintain the activity and integrity of pathogen, and can be used for virus culture and isolation. Inactivated type: it can split pathogen instantly and release nucleic acid, and the protective agent can prevent nucleic acid from degradation. [Scope of use] The Virus Transport Media can be used for the collection, preservation and transportation of nasopharyngeal pathogen specimens such as new coronavirus, influenza, bird flu, hand-foot-mouth disease, measles and so on. Non-inactivated type: On the basis of Hank's, BSA (bovine serum albumin) amino acids, vitamins and other nutrients are added to maintain the virus' activity over a wide temperature range and maintain the originality of the sample to the greatest extent and can be used for virus nucleic acid extraction and detection, virus culture and isolation. Inactivated type: By fully mixing the collected samples with virus lysate and virus nucleic acid preservation solution, the virus in the samples can be inactivated, and the integrity of virus nucleic acid in the samples can be effectively guaranteed. The collected samples can be transported and preserved for a long time under normal temperature. The preserved viral RNA samples can be widely used for genetic testing, enzyme-linked immunoassay (ELISA), PCR testing, ect. [Storage conditions and time] Non-inactivated type: Store at 4-25 ℃. It shall be transported to the laboratory within 48 hours under 2-8 ℃ after sampling, or stored under - 70 ℃. Inactivated type: 30 days at normal temperature