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Latest company new about What are the advantages of acridine esters in luminescent reagents
2021/03/01

What are the advantages of acridine esters in luminescent reagents

Acridine ester is a kind of important chemiluminescence reagents, which has high quantum yield and high chemiluminescence efficiency. As a chemiluminescence marker, the luminescence system is simple, the natural background is low, the interference is less, and the signal-to-noise ratio is high. When used as a chemiluminescence marker, it has the advantages of easy coupling, simple labeling, good stability, and less influence on its luminescence performance In the presence of sodium hydroxide and hydrogen peroxide. In addition, acridine ester chemiluminescence reagents have good stability and are easy to store.   According to the different substituents, acridine substitutes commonly used as chemiluminescence markers can be divided into two categories: acridine ester and acridine sulfonamide. They all share the same acridine ring. Their luminescence mechanism is the same: in the alkaline H2O2 solution, when the molecule is attacked by hydrogen peroxide ion, the unstable dioxane is generated, which is decomposed into CO2 and n-methylacridone in the electron excited state. When it returns to the ground state, it emits photons with the maximum emission wavelength of 430nm.     The characteristics of these compounds are as follows:    ① In the luminescent reaction, the non luminescent substituents attached to the acridine ring are separated from the acridine ring before the formation of the electron excited intermediate, that is, the non luminescent part is separated from the luminescent part, so the luminescent efficiency is not affected by the substituent structure.   ② The chemiluminescence of acridine esters or acridine sulfonamides can be obtained in dilute alkaline solution with H2O2 without catalyst. Therefore, it has many advantages in chemiluminescence detection.   The main advantages are as follows:   1. Low background illumination and high signal-to-noise ratio   2. The interference factors of luminescent reaction are few   3. Fast and concentrated light release, high luminous efficiency and high luminous intensity   4. It is easy to bind with protein, and the photon yield does not decrease after binding, thus increasing the sensitivity   5. The solid phase separation agent is very fine magnetic powder, which not only increases the coating area and accelerates the reaction, but also cleans at the same time.
Latest company new about Carbomer reserve price promotion
2021/02/28

Carbomer reserve price promotion

The only difference between Desheng cabomer and imported brands is the price. The spot price of Desheng cabomer is as low as 130 yuan / kg, and the quantity is limited, so we miss the next batch. For cosmetic raw materials, pharmaceutical gel, hand gel free, etc., please contact the German Sheng website or the phone left by the network.   Desheng has been committed to the research of polyacrylic acid. Besides the serum separation gel series, Carbomer series is also a long-term series. With 15 years of R & D and production experience, Desheng carbomer products are more reliable!   Carbomer products were first produced abroad, and now a foreign brand still controls more than 80% of the market. The reason for this situation is nothing more than the gap in technical ability. After continuous research and development efforts in recent years, Desheng has finally been able to achieve the situation of "no one, no one, no one, no one, no one, no one, no one, no one, no one, no one, no one, no one, no one, no one, no one, no one, no one, no one, no one, no one, no one, no one, no one, no one, no one, no one Price is also to expand the reputation and win by quantity. I hope more customers can know Desheng.     Desheng put forward that the preferential price of carbomer products is in the end, the product quality is guaranteed to be the best, free samples, perfect after-sales service, if you have problems, you can contact a professional one-to-one sales manager for full-time service, and for product problems, the whole process of technical participation, you know, we communicate with each other, you don't understand, we understand, we teach!   As a widely used carbomer product, Desheng is very welcome to retail and wholesale, small quantity and large quantity. We also hope that all partners can take time to visit our factory, so as to further win-win cooperation. Desheng cabomer's regular guarantee is 10kg / bag. According to the customer's requirements, it can also customize the product index and separate the packaging according to the special requirements.   According to the change of market price, the price will increase or decrease according to the demand of customers. Please call our friends to inquire. It's also very good to add a waiting material supplier!
Latest company new about What are the types of Virus Transport Medias?
2021/02/27

What are the types of Virus Transport Medias?

Since the outbreak of the new coronavirus, the Virus Transport Media has played an important role. First, the nasal and pharyngeal swabs were used to sample, and the samples were put into the sampling tube added with the Virus Transport Media for sample protection, which improved the accuracy of nucleic acid detection. Virus Transport Media is a solution medium used for virus sampling, transportation, storage and detection. If it is added into the virus sampling tube, what kinds of Virus Transport Media are added?   There are two kinds of Virus Transport Medias, inactivated and non inactivated. There are many kinds of Virus Transport Medias on the market. The following is a brief introduction of several principles for the selection of Virus Transport Medias. Non inactivated preservation solution: Based on Hank's, the non inactivated virus does not contain lysate, and is supplemented with nutrients needed by virus, such as BSA (bovine serum albumin) amino acids, vitamins, etc. it can maintain the activity of virus in a wide temperature range and keep the original sample to the greatest extent. It can be used for virus nucleic acid extraction and detection, virus culture and isolation.   Characteristics of non inactivated preservation solution: 1. The virus can remain active and can be used for detection or virus isolation; 2. There was no inhibition on subsequent nucleic acid amplification, which could be matched with direct amplification reagent; 3. After the swab is added, it needs to be refrigerated to detect the main components as soon as possible.   Inactivated preservation solution: Inactivation preservation solution can fully mix the collected samples with virus lysate and virus nucleic acid preservation solution to inactivate the virus in the samples, and effectively ensure the integrity of virus nucleic acid in the samples. The collected samples can be transported under normal temperature and preserved for a long time. The preserved virus RNA samples can be widely used in gene detection, enzyme-linked immunosorbent assay (ELISA), PCR detection and so on. The inactivation preservation solution can be divided into guanidine containing solution and non guanidine containing solution.   1. Guanidine salt (1) The virus can be split and inactivated instantaneously to reduce the risk of sampling; (2) The viral nucleic acid could be stored at room temperature for 2 weeks; (3) It can match most nucleic acid extraction reagents.   2. Non guaiac salt (1) The virus can be inactivated instantaneously to reduce the risk of sampling, and the virus may recover its infectivity after dilution; (2) The viral nucleic acid could be stored at room temperature for 2 weeks; (3) It can match most nucleic acid extraction reagents.   3. Direct expansion preservation solution (1) The virus can be inactivated instantaneously to reduce the risk of sampling, and the virus may recover its infectivity after dilution; (2) The viral nucleic acid can be stored in cold storage for 24-48 hours; (3) It can be directly added into nucleic acid amplification system as template; (4) Most of the nucleic acid extraction reagents and releasing agents were matched.   I believe that after reading the above explanation, we will have more basis for choosing the correct and applicable preservation solution. Desheng is a manufacturer of Virus Transport Media, which can provide inactivated and non inactivated preservation solutions. We can accept customized samples from customers, and also provide disposable virus sampling tube and nasopharyngeal swab, etc. to provide customers with one-stop service. If you need, you can click the official website for consultation or contact directly Our professional sales staff.
Latest company new about Hot sale of Desheng nsp-dmae-nhs acridine ester products
2021/02/26

Hot sale of Desheng nsp-dmae-nhs acridine ester products

The recent hot sale of acridine ester nsp-dmae-nhs is something I didn't think of. Why I didn't think of it is not because this product is not good, but because Desheng has developed and produced acridine ester products with six different groups, but only nsp-dmae-nhs has top sales.   As of yesterday, the warehouse has been cleared, which is also the product that has been cleared quickly since 2021. It has been replenished three times, but each time it can be sold out in a short time.   In recent years, the development of chemiluminescence is not only in the research and development of instruments, innovation, but also in the use of reagents. More advanced enterprises adopt the world's more mainstream luminescence reagent acridine ester, which is not only simple in labeling, high in luminous efficiency, but also its stability is incomparable with other luminescence reagents.   Product packaging   Desheng also produces luminol series products, but there are some limitations compared with acridine ester. The luminous efficiency of acridine ester is 4-5 times that of luminol, and the labeling method of luminol is more complex than acridine ester. With the continuous progress of human beings, complex things think of simpler evolution and development.   Desheng nsp-dmae-nhs is a golden powder in the normal state. Its texture is very fine and bulky. Its purity is more than 98% by HPLC. It has no peculiar smell. The market feedback is good. Nsp-dmae-nhs is very stable at pH 7.0, and its water solubility test is added in this model, which can be carried out in water in the detection of antigen nucleic acid.   Compared with other acridine salts, acridine hydrazide and nsp-dmae-nhs have moderate price and better luminous efficiency. Desheng has a large stock and more favorable price. Desheng has a professional R & D team, such luminescent reagent products are developed and produced by our company, and the quality is guaranteed. The products can be repacked according to the needs of customers. Of course, due to the high value of acridine ester, small repacking will calculate the loss, and the price will be higher.
Latest company new about Application and scope of carbomer in pharmacy
2021/02/25

Application and scope of carbomer in pharmacy

Carbomer, also known as polycarboxyethylene, is a polymer formed by chemical crosslinking of acrylic acid or acrylate with allyl, including polyacrylic acid (homopolymer) and long-chain alkanol acrylate polymer (copolymer). It has high efficiency of thickening, gel, suspension and so on. Because of its excellent water absorbency and suspension, it has become one of the main raw materials in the hand sanitizer handwashing gel which has been widely used during the epidemic. The former Desheng Xiaobian has talked about the application of carbomer in cosmetics and washing liquid, and it is no longer described today. The following is mainly about the application of carbomer raw materials in pharmaceutical products.   Desheng carbomer powder and gel product map   Carbomer is widely used in topical emulsion, cream and gel. In the neutral environment, carbomer gel system is a good gel matrix. It is crystal clear and smooth. It is very suitable for the preparation of cream or gel. At the same time, it is widely used in topical administration, especially in skin and eye gel, because of its simple process, good stability and comfortable feeling.   Carbomer is mainly used as a water-soluble matrix for ointment, gel, etc., as well as adhesives and film coating materials for tablets, granules, slow release skeleton materials, emulsifiers, thickeners, suspending agents, etc.   1. As adhesive and film coating material   As a binder for granules and tablets, Carbomer dosage is mainly determined by the physical and chemical properties of the main drug and the requirements of prescription design, and the general dosage is 5% ~ 10%.   2. As a sustained-release framework material   Carbomer formed a special network structure due to the covalent crosslinking between the chains. The gel formed by hydration and expansion, and used as a hydrogel skeleton material in the sustained-release control agent, and controlled the release of the drug through the gel layer formed. Carbomer, as a slow-release material, can increase the choice of prescription, generally 6% ~ 10% of the dosage, has good compressibility, good compatibility with other excipients, and can make the drug release zero or nearly zero (zero release: the drug release rate does not change with time, that is, the drug release rate remains constant in the drug release cycle).   The type and dosage of carbomer can affect the drug release. The sustained release effect of 974P is stronger than that of 934p. The release rate of tablets containing 10% carbomer 974P is similar to that of tablets containing 30% 934p. In addition, the solubility of the drug and the pH value of the medium also affect the drug release.   3. Matrix for ointment, suppository, gel and so on.   1% carbomer solution pH about 2.5~3.0, adding sodium hydroxide, potassium hydroxide, sodium bicarbonate, borax and triethanolamine and other alkali regulators, viscosity increased to form gel, as thick as pH 6~12, can be used as a water-soluble semisolid preparation matrix, the dosage is 0.5%~3%. The gel matrix has the advantages of rapid release, no greasy, easy to spread, no irritation to skin and mucosa, and can be mixed with aqueous solution and absorb tissue exudates, which is good for removing the secretion.   4. As emulsifier, thickener and suspending agent   Carbomer can be used as an auxiliary emulsifier for O/W type (water in oil) emulsifier in emulsion. The dosage is 0.1%~0.5%. It can be used as thickener and suspension in solution and suspension, and the dosage of gel is usually 0.5%~2%, and the dosage of suspending agent is 0.5%~1%.   In addition, Carbomer, as a carboxyl polymer, has strong bioadhesive properties. Carbomer 934 has strong bioadhesive properties. The bioadhesive agents based on carbomer 934 have been widely used in clinic, such as nasal bioadhesive agents, vaginal bioadhesive agents, rectal bioadhesive agents, oral or oral bioadhesive agents, etc.   Desheng as a professional manufacturer of cabom, can provide high quality products and professional services, as well as rich export experience. Compared with the products of other manufacturers, it has higher cost performance. Now, in order to expand the brand awareness, low price promotion is implemented, and the price is as low as 100 yuan / kg. Don't miss the rare opportunity, you can click the official website to consult or call for details.
Latest company new about TMB, luminol, phenolphthalein - forensic blood test
2021/02/24

TMB, luminol, phenolphthalein - forensic blood test

Blood test is one of the most common forensic physical evidence tests in criminal cases. Blood chromogenic agent is used to quickly detect potential blood stains, blood fingerprints, blood fingerprints, etc. at the scene of the crime, which can provide important clues and basis for quickly restoring the scene of the crime and case investigation. TMB, luminol and phenolphthalein are common blood stain color reagents. They are the right assistants of forensic examination and evidence collection.   The full name of TMB is 3,3 ', 5,5' - tetramethylbenzidine, cas54827-17-7. TMB is a new and safe chromogen reagent, which is widely used in clinical laboratory, criminal detection and other fields.   TMB development method is a commonly used blood test method. Its principle is that the blood contains catalase and hematoporphyrin, which can catalyze hydrogen peroxide to release primary oxygen. Primary oxygen reacts with tetramethylbenzidine (TMB) to produce tetramethylbenzidine blue, which makes the blood appear turquoise blue.   Luminol, also known as luminol, cas521-31-3. Luminol can react with a variety of oxidants, which has high quantum yield and good water solubility.   Luminol luminescence method is a very common blood test method, its principle is that blood contains hemoglobin, hemoglobin contains iron, and iron can catalyze the decomposition of hydrogen peroxide into water and monooxygen, monooxygen can oxidize luminol, showing blue-green fluorescence.   Luminol luminescence method is extremely sensitive. Even if the criminal has cleaned up the blood on the scene, forensic and other criminal investigators can still rely on luminol to make the blood invisible. Luminol luminescent method to restore blood is also the most common and exciting scene in criminal investigation movies and TV series.   Phenolphthalein, CAS 77-09-8. Phenolphthalein is a kind of weak organic acid, which is colorless in acidic and neutral solutions, purplish red in alkaline solutions, orange in very strong acidic solutions and colorless in very strong alkaline solutions. Human blood is alkaline, so phenolphthalein can appear red when it meets with blood.   Chemical reagent coloration is a common method of blood test in the field of criminal investigation. TMB, luminol, phenolphthalein and other chemical reagents are useful weapons to find the clues of cases, and become the right assistants of forensic staff. Desheng is an old manufacturer of chemiluminescence reagents. Besides the above TMB and luminol luminescent substrates, Desheng can also provide isoluminol and six acridine esters. Welcome to order!
Latest company new about How much is the carbomer 940
2021/02/23

How much is the carbomer 940

We should be familiar with the word "carbomer", because it is widely used, so the daily shampoo, shower gel, cream, lotion, and various kinds of medical gels, such as skin care cosmetics, and so on, contain the appearance of carbomer. Because carbomer has strong water absorbency and good gel matrix after dissolving, it has been found in this year's hot washing and disinfectant gel hand sanitizer. This has made him a lot more famous.   Carbomer is a white, loose, slightly odorous powder with strong hygroscopicity and an average moisture content of 8%. According to the different structures of polymer monomers, they can be divided into two categories: carbomer 900 series and carbomer 1300 series. Different types and uses of CP products can be obtained by controlling the relative molecular weight and crosslinking degree of polymer. Carbomer 940 is the most consulted product in carbomer series. According to the consultation process of purchasers, they are most concerned about the price of Carbomer, and then the quality. Is there any carbomer with high quality and low price?   The answer must be yes, there is no doubt that there are few. Desheng is the manufacturer of cabom, which has very little high quality and low price. How much is Desheng cabom 940?     Desheng at the end of the year to expand brand awareness, low price promotion of carbomer price 100 yuan / kg, this activity for carbomer 940 and 980. See if this is full of doubts about the price of Desheng cabom. Don't doubt it. Keep looking.   Desheng was founded in 2005 as a new enterprise specializing in polyacrylic acid material products. So far, it has developed three generations of serum separation gel for different purposes and carbomer products for different purposes. Moreover, the indicators of carbomer can meet the requirements of international brands, and at the same time, it can support individual index customization.   Compared with other products, De Sheng carbomer can be found to be more white and fluffy, and the gel after dissolution is more transparent than other products. In addition, Desheng has perfect after-sales service. Desheng promises to return and replace any quality problems. It can be purchased in small quantities, and can also enjoy ultra-low price discount by signing annual contract. Desheng cabom has good product quality and one-stop purchasing service support. It is the right choice to choose Desheng for both customers' direct orders and traders' purchases.   If you want to find products that can guarantee quality, price and discount, you must be right to choose Desheng. This discount is only one time this year, and you will never miss it any more. Desheng can also provide trial products for free. If you have any concerns, you can contact customers first to apply for sample trial. What are you waiting for? Click on the official website to contact customer service for consultation and order.
Latest company new about In addition to quality and output, Desheng cabomer also has favorable price
2021/02/22

In addition to quality and output, Desheng cabomer also has favorable price

Carbomer is an important raw material in our daily chemical products, especially after the epidemic, more and more people are familiar with it. Its most famous battle is its absence, resulting in a shortage of disposable hand gel on the market, and in short supply. This also makes many businesses see its business opportunities, and they have a thief's heart to cabom. In the period of money and no goods, many manufacturers are merciless, and use other products to impersonate carbomer, and sell them at a high price. Because of these reasons, many customers are deceived and cold hearted. They don't believe in carbomer's products and always have a skeptical attitude. Today, I'd like to take you to Desheng, the real enterprise that produces cabom.   Desheng cabom production base   Desheng biochemical is a chemical reagent company established in 2005. It has been engaged in the R & D and production of polyacrylic acid. Up to now, it has developed three generations of serum separation gel for different purposes and carbomer products for different purposes. Conventional production is carbomer 940 and carbomer 980, daily production can reach 3-5t.   Desheng has a professional R & D team with 6 professional R & D personnel and 10 production personnel. In terms of product quality, what we uphold is that you pay for good things and we pay for bad things. No matter what problems we encounter, we can solve them for you at the first time. What we do is word of mouth, not a business.     Since carbomer is developed and produced by our company, it supports customization of some indicators for different industries and uses. And we produced carbomer powder is obviously white, and the powder is more fluffy and delicate. In the configuration of solvent, the transparency is also much higher than that of similar products. The conventional carbomer is made into gel, the appearance is more transparent, and the viscosity can be customized according to individual indexes. In addition, Desheng has perfect after-sales service. Desheng promises to return and replace any quality problems. Can apply for free sample trial, do try before buying.   We have the advantage of quality and output, the price is to bring you a surprise. Before the year, the preferential price was over tons, and the price was as low as 130 yuan / kg. This preferential price lasts for one month, from February 25, 2021 to February 25, 2021. Don't doubt what you see. This is our greatest sincerity.
Latest company new about High-quality virus transport media manufacturers should choose this way!
2021/02/22

High-quality virus transport media manufacturers should choose this way!

A sudden epidemic caused the virus transport media, and more and more businesses value this market, so batches of virus transport media manufacturers have emerged on the market. This is bound to dazzle buyers. How to choose high-quality products The manufacturer of virus transport media is a very important issue. Desheng tells you several issues that should be paid attention to in purchasing.   1. Is there enough cooperating manufacturers Whether the quality of the product is good or not depends on the sales volume and the cooperating customers. If there are many cooperating customers and the sales volume is considerable, then the reputation of this manufacturer in the industry must be very good. Desheng’s virus transport media has sold a total of 100 Wansheng relies on the trust of customers in the quality of Desheng. After using Desheng’s virus preservation solution, many customers feel very satisfied with the quality and price, and recommend it to other customers. Bai, Desheng’s reputation continues to spread in the industry, and the number of customers and sales gradually increase. 2. Is there enough stock and whether the delivery is timely During the epidemic, the demand for virus transport media is huge, and many customers’ inquiries are more than 1,000 liters. If there is no sufficient stock to support, customers will choose other manufacturers in a blink of an eye, even if they are willing to wait, when the goods are insufficient Under the conditions, if the delivery cycle is long, on the one hand, it will harm the interests of customers. On the other hand, the customer’s sense of buying experience will be very bad. After Desheng upgrades and reforms the equipment, the monthly output can reach the ton level. The delivery is very timely, so don't worry about it at all.   3. Can a trial package be provided Manufacturers who can provide trial sets are rooted in their high trust in their own quality. Desheng believes that only good product quality can tell you with confidence that if you have doubts about product quality, you can try it first. I will come to you to order in large quantities. If the trial is not good, we will do it to make you feel good. Desheng can provide trial equipment. Whether the product is good or not will we know after the trial. Desheng believes that good wine is not afraid of deep alleys, and good products are not afraid of trial.   Desheng took action during the epidemic to ensure the supply of virus transport media in the market. There are currently two models. The inactivated type is characterized by protecting the nucleic acid of the virus, and the non-inactivated type is protecting the integrity of the entire virus. Everyone Can be checked test demand selection.
Latest company new about Phosphor acridine ester nsp-dmae-nhs 194357-64-7
2021/02/21

Phosphor acridine ester nsp-dmae-nhs 194357-64-7

The luminescent agent acridine ester 194357-64-7 is a kind of luminescent substrate reagent used in chemiluminescence experiments. Its CAS number is followed by its parent acridine ester. According to the different substituent groups, there are many derivatives with different characteristics. This one is called acridine ester nsp-dmae-nhs, which is one of the more commonly used ones.   Chemiluminescent immunoassay CLIA has gradually surpassed enzyme linked immunosorbent assay as the mainstream in vitro diagnostic detection method. CLIA detection method is relatively simple. It does not need to introduce external light source, and only needs the instrument that can detect light to complete the detection, so it is easy to automate the experimental equipment. Moreover, chemiluminescence has higher sensitivity, which can be used for both qualitative and quantitative analysis.     Structure of acridine ester nsp-dmae-nhs   Acridine ester is usually yellow powder, because it is sensitive to light, in order to extend the shelf life, it is usually packaged in opaque brown bottle and stored at low temperature. Compared with luminol, the chemiluminescence efficiency of acridine ester is five times or more, and it can be directly oxidized by hydrogen peroxide in alkaline condition without enzyme catalysis.   Acridine ester nsp-dmae-nhs is a kind of acridine ester containing - NHS group. NHS, namely N-hydroxysuccinimide or N-hydroxysuccinimide, can be directly connected with the primary amino group of protein or antibody, which is convenient to label antibody or protein. -NSP is a propanesulfonic acid group linked to the nitrogen atom of acridine parent. Compared with the traditional acridine ester ae-nhs, NSP has better hydrophilicity. The structure of inner salt of propanesulfonic acid increases its water solubility, which makes it water-soluble with the markers formed by antibody and nucleic acid. The later luminescence detection can be carried out in water.   In fact, the earliest chemiluminescence was found in animals, such as fireflies in summer. Now it has become bioluminescence. In essence, a series of biochemical reactions have taken place in the substances in the body, resulting in the chemiluminescence phenomenon.   At the end of the 19th century, it was found that abiotic organic compounds can also produce chemiluminescence, such as lofenine, luminol, N, n-dimethylaacridine nitrate, acridine ester and so on. Among them, lucigenin is also an acridine compound.   In addition to the acridine ester nsp-dmae-nhs, Desheng also develops and sells five different types of acridine esters, which are also the ones with better market feedback. However, it does not rule out that more types of acridine esters will be developed and put into the market in the future.
Latest company new about Characteristics of heparin anticoagulant in blood collection tube
2021/02/21

Characteristics of heparin anticoagulant in blood collection tube

Heparin anticoagulant is a kind of reagent used for blood anticoagulation. It is usually used for blood collection tube anticoagulation. It can also be used for medical anticoagulation and beauty products. Heparin was first discovered and named from the liver of animals. It is a kind of mucopolysaccharide sulfate, a natural anticoagulant substance in the animal body, and has unique properties compared with other anticoagulants.   Heparin anticoagulant is different from other anticoagulant sources:   Anticoagulants such as dipotassium EDTA, sodium citrate or potassium oxalate can be directly synthesized or extracted from plants. The sources are relatively wide and the cost of raw materials is not high. The difference between different products is mainly reflected in the purification process and technology; while heparin Anticoagulant is different. It needs to be extracted from the animal body, usually from the small intestine of sheep or pig, and the content is very small. It takes thousands of pigs to extract one kilogram of heparin. There are two main types of heparin anticoagulants commonly used: heparin sodium and lithium heparin anticoagulants.   Bottled heparin sodium   Application characteristics of heparin anticoagulant:   Heparin is a physiological anticoagulant with antithrombin effect and inhibits the activation of coagulation factors V, VIII, XI and other factors, and promotes fibrinolysis. Heparin anticoagulant is usually its sodium, potassium, lithium, ammonium salt, such as heparin sodium, heparin lithium, etc., of which heparin lithium is the best.   Heparin anticoagulant affects the volume of blood cells and rarely produces hemolysis. It is often used for hematocrit, blood pH, blood gas analysis and other biochemical determinations. It is also suitable for red blood cell osmotic fragility tests. Add 1 mL of a solution containing 1 g/L of heparin to each tube, and dry it below 60 ℃ for later use to prevent 5-10 mL of blood from clotting. Heparin anticoagulant blood is not suitable for blood smear examination, because it will have a bluish background during Wright's staining, and it is not suitable for coagulation factor examination.   Preservation of heparin anticoagulant:   Heparin anticoagulant is the same as other anticoagulants. The liquid is easy to absorb moisture or even deteriorate and needs to be sealed and stored. Moreover, because heparin is a kind of mucopolysaccharide, it can provide nutrition for microorganisms, which is conducive to bacterial reproduction. Therefore, new heparin anticoagulant tubes need to be used. The configured heparin solution, the heparin anticoagulant is ready to use.   Compared with other anticoagulants, heparin anticoagulant is more expensive and has better performance for organisms, but it does not mean that it can replace other anticoagulants, but different anticoagulants have different applications in different situations According to the different needs of blood collection tube enterprises, Desheng provides a variety of anticoagulants such as heparin sodium, lithium heparin, dipotassium EDTA, sodium citrate, and a full set of blood collection reagents such as serum separation gel, coagulant, and siliconizing agent.
Latest company new about Pharmaceutical application of trometamol organic salt
2021/02/20

Pharmaceutical application of trometamol organic salt

Tris (trimethylaminomethane, cas77-86-1), as a common biological buffer, is not only widely used as a solvent for nucleic acid and protein, but also one of the main components of protein electrophoresis buffer. In addition, Tris can also produce a variety of cosmetics, chemicals, pesticides, medicine, coating preparation and other products, and is an important intermediate for the preparation of surfactants, vulcanization accelerators, reducing agents and some drugs.   Tris is not only used as a buffer, but also in the field of medicine. As a drug, Tris is also known as tromethamine. When it is called tromethamine, it can be used for the prevention and treatment of metabolic acidosis and respiratory acidosis, and has a reliable alkalizing effect on urine.   Because the alkalinity is too strong, the preparation can only be injected intravenously, and intravenous injection is more irritant and has more adverse reactions. Yunnan University of traditional Chinese medicine has prepared an organic salt of tromethamine, which can be taken orally and injected intravenously. It not only reduces the irritation and side effects of tromethamine, but also has the functions of alkalizing urine, preventing hyperuricemia and gout, and resisting peptic ulcer.   tromethamine powder   The organic salt of tromethamine is prepared by mixing the organic acid acetic acid or lactic acid which can be completely degraded by the body with tromethamine. After injection or oral administration, the acetic acid or soft acid in the solid or solution of tromethamine can be completely and rapidly degraded and enter the liver in the form of salt, and free tromethamine can be obtained after discharge. Acetic acid and lactic acid are completely metabolized into carbon dioxide and water, and the degradation rate of acetic acid is faster than that of lactic acid. Because of its high polarity, stable chemical properties and not easy to be metabolized by the body, the remaining part of tromethamine can alkalize the blood.   Tromethamine entering the body is mainly excreted through urine, and it is not easy to be reabsorbed. Then tromethamine can alkalize the renal tubular environment and dissolve the deposited acidic substances, so as to be discharged from the body. Promoting renal excretion of uric acid is an important strategy for the prevention and treatment of hyperuricemia and gout.   In addition, the organic salt of tromethamine is a weakly alkaline substance with a pH similar to that of blood. Compared with the direct use of tromethamine, the irritation is very low, which can avoid or greatly reduce the adverse reactions and safety problems caused by too strong alkalinity. Moreover, the organic acid solution of tromethamine has a strong pH buffering function, can neutralize or buffer gastric acid, and will not produce gas in the process, so it has the effect of anti peptic ulcer.   Tris (tromethamine) is widely used in medicine, whether as a biological buffer, as a drug itself, or as a pharmaceutical intermediate, or as a pharmaceutical excipient, tromethamine plays a huge role in the pharmaceutical field. Desheng is a professional manufacturer of tris (tromethamine), which has been implemented in batch production, with an average daily output of 1t, and sufficient in stock. Welcome to consult order.
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