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Latest company new about Development and advantages of DMAE-NHS acridine chemiluminescent reagents
2021/02/06

Development and advantages of DMAE-NHS acridine chemiluminescent reagents

Acridine ester DMAE-NHS is a typical acridine chemiluminescence reagent that has been commercialized. It has the characteristics of high sensitivity of chemiluminescence analysis, simple equipment, no light source to avoid the influence of astigmatism, and high reproducibility. Important fields such as environmental monitoring, clinical analysis, and biochemistry have been widely used.   Acridine chemiluminescence reagents for detection Development of acridine chemiluminescence reagents: Acridine Since Grebe and Carlo discovered acridine in the high-boiling fraction of coal tar in 1870, acridine and acridine derivatives have attracted a lot of scientific and technological interest, and have subsequently been widely used in the development of anti-cancer drugs and antibacterial agents. , Immunodiagnosis and other fields. Acridine chemiluminescent reagents are a technologically advanced luminescent marker for proteins, antibodies, and nucleic acids in immunodiagnosis.   Advantages of acridine ester DMAE-NHS:   Compared with other luminescent substrates such as luminol and AMPPD, acridine-based luminescent reagents have high luminescence intensity, high efficiency, low background interference, no need for enzyme catalysis and enhancers, high signal-to-noise ratio and label binding Stability and other advantages. Moreover, after structural modification of acridine compounds, a chemiluminescence probe is made, which is not only suitable for labeling small molecules, but also for labeling biomacromolecules with chemiluminescence, which can label proteins, proteins under neutral or slightly alkaline conditions. Biological macromolecules such as nucleic acid and polypeptide, and the fluorescence quantum yield and biological activity of the labeled substance will not be damaged.   Comparison of acridine ester DMAE-NHS with other acridine luminescent reagents:   There are more than ten kinds of acridine chemiluminescence reagents commercialized on the market, of which 6 are developed and produced by Desheng, including 3 acridine esters and 3 acridine sulfonamides. Compared with other luminescent reagents, the acridinium ester DMAE-NHS is characterized by containing NHS groups, which can be directly connected to the primary amino groups of proteins or antibodies for labeling. There are also some differences in hydrophilicity from acridine sulfonamides. Choose the appropriate acridinium ester for the type of protein or antibody.   It should be noted that Desheng’s acridinium ester DMAE-NHS has improved hydrophilicity on the basis of traditional acridinium ester, but its dissolution process still needs to be strictly anhydrous. In addition, mercapto groups may cause acridine ester hydrolysis. Mercaptoethanol cannot be used, and care should be taken if the labeled protein contains sulfhydryl groups.
Latest company new about Application and packaging of carbomer 940 -- supplier of Desheng carbomer
2021/02/05

Application and packaging of carbomer 940 -- supplier of Desheng carbomer

  Carbomer 940 is used in jelly gel formation. It can be used as an excellent floatation agent, stabilizer, emulsifier and matrix for pharmaceutical excipients. It is also an effective water-soluble thickener. 0.5% of the added amount can make jelly gel with jelly effect, slightly acidic, and the pH value of the dispersed system in 0.5% water is 2.7 - 3.5.   Recommended dosage of carbomer:   Generally, the addition amount is 0.2 to 1.0%, and in most cases, 0.2 to 0.5%. The 0.2 to 2% amount of carbomer resin is used as an emulsifier. The amount of 0.2 to 2% of carbomer resin is used as thickener. The 0.2 to 2% amount of carbomer resin is used as ointment. The 0.2 to 2% amount of carbomer resin is used as a gel.   carbomer gel     How to use carbomer 940:   2% carbomer gel (50ML):   1. Weigh 1g carbomer dry powder and place it in a dry beaker with a scale of 50ml. If there is caking, please grind it with a spoon.   2. Add 25ml pure water, stir while adding, make carbomer fully absorb water and dissolve. This step is very critical. You must make carbomer absorb water fully. Generally, after adding water and stirring, you can put it for a few hours (you can configure it before going to bed at night, and it can be deployed the next day). Carbomer can fully dissolve. If you want to speed up, you can use a water bath to heat. It will be faster to stir while heating. Of course, even if heating can accelerate the process of carbomer's water absorption and swelling, it will take 10-30 minutes.   3. Drop the lye with the drop tube and stir it side by side to measure pH value. When the PH7 is adjusted, the gel is successful. (triethanolamine is enough for lye).   matters needing attention: 1, Carbomer must interact with the alkali triethanolamine to form a solid gel texture. 2. It is not resistant to acids, electrolytes, salts and other substances. Once it meets with salt, it will decompose into water   Product packaging Packaging and storage:   Carbomer has a strong hygroscopicity. When storing, pay attention to sealing, and be careful to avoid moisture absorption and caking in the exposed air. If there is slight caking, it can become loose powder by gently patting and pressing, which will not affect the thickening effect. Once the product is used, it is best to place it in a sealed container with desiccant.   Transportation:   Desheng carbomer is packed in non-toxic polypropylene and nylon co extruded plastic bags, moisture-proof and airtight, and then packed in cardboard boxes. Carbomer is a polyelectrolyte, and sometimes static electricity is carried by rubbing or extruding resin particles. In case of spilling, please sweep up the dry powder with a broom first, and do not wash it with water, otherwise it will form a very slippery thin layer on the ground or equipment.   Desheng carbomer is more than 100 yuan / kg in tonnage, with large quantity and more favorable price. The carbomer 940 and 980 powders produced by Desheng carbomer are whiter and more fluffy than those in the market, and the transparency after dissolution is better.  
Latest company new about What is the difference between EDTA dipotassium and its hydrate in blood anticoagulant
2021/02/05

What is the difference between EDTA dipotassium and its hydrate in blood anticoagulant

Dipotassium ethylenediaminetetraacetate is usually referred to as dipotassium EDTA. When purchasing reagents, we will find that it has two CAS numbers. One of these is actually EDTA dipotassium crystalline hydrate, but many people on the Internet confuse the two. , It becomes a mixed use of the two numbers. What is the difference between the two and will it affect the use?   The dipotassium EDTA is CAS 2001-94-7, and the dipotassium EDTA dihydrate is CAS25102-12-9. The difference between the two is that one molecule has two crystal waters. Dipotassium EDTA powder is easy to absorb moisture and become crystal water. It is relatively stable when it contains two crystal waters. For blood anticoagulants, EDTA dipotassium containing crystal water is generally used.     Purchase details of blood anticoagulant EDTA dipotassium   Other anticoagulants such as tripotassium EDTA and sodium citrate have similar situations. In fact, when most salts or other compounds precipitate crystals from aqueous solutions, the crystals often contain a certain number of water molecules, which is crystal water; many mineral salts in nature are more stable when they exist in the form of crystal hydrates.   The number of crystal water of crystal hydrate is usually related to the vapor pressure of water in the environment. As the vapor pressure increases, the number of water molecules also increases. The stability of crystal hydrate is related to temperature, cation and anion. Generally, potassium ions do not have crystal water (dipotassium EDTA and tripotassium EDTA both have crystal water, with exceptions). Sodium ions often have crystal water, such as their carbonates. The number of crystal water in salts is related to temperature, 34 There are 10 crystal waters below ℃, and no crystallization water above 34℃. Some crystal hydrates will automatically lose crystal water in dry air, that is, weathering; some will automatically lose crystal water, deliquescence or moisture absorption.   When used as a blood anticoagulant, EDTA dipotassium or tripotassium both need to be prepared with water to prepare a solution. Whether it contains crystal water will not affect its anticoagulant effect. However, in the test and calculation, the molecular weight of EDTA dipotassium without water and with crystal water is different. Dipotassium without crystal water has stronger moisture absorption and is not as stable as hydrate. If it absorbs moisture, it may cause calculation errors.   Special attention should be paid to the EDTA dipotassium CAS number when purchasing. Don't think that the CAS number is not the same as if the CAS number is inconsistent. Be sure to check repeatedly. The EDTA dipotassium, tripotassium, and sodium citrate produced by Desheng are easy to absorb moisture in the air, so it is sealed and stored. Please pay attention to it when using it.
Latest company new about Agarose gel electrophoresis and DNA
2021/02/04

Agarose gel electrophoresis and DNA

Agarose gel electrophoresis is a commonly used method for isolation, identification and purification of DNA fragments. When DNA molecules are swimming in agarose gel, they have charge effect and molecular sieve effect. DNA molecules are negatively charged in pH solution above isoelectric point and move to the positive electrode in the electric field. Due to the repetitive structure of the glycophosphate backbone, the same amount of double stranded DNA has almost the same net charge, so they can move to the positive direction at the same speed.   Different concentrations of agarose gel can separate DNA fragments from 200bp to 50kb. In the agarose solution, low concentration of ethidum bromide (EB) was added into the agarose solution. The DNA band of 10NG could be detected under UV light. In the electric field, the negatively charged DNA migrated to the anode in pH8.0.     Agarose gel has the following characteristics: (1) the molecular size of DNA in the gel matrix is inversely proportional to the value of the base logarithm, and the larger the molecule, the slower the migration.   (2) agarose concentration in a specific size of linear DNA molecule is different from agarose gel in different concentrations. The logarithm of electrophoretic mobility (U) of DNA is linearly related to gel concentration (T).   (3) When the voltage is low, the migration rate of linear DNA fragments is proportional to the applied voltage. However, with the increase of electric field intensity, the mobility of DNA fragments with different molecular weights will increase in different ranges. With the increase of voltage, the effective separation scope of agarose gel will be reduced. In order to maximize the resolution of DNA fragments larger than 2KB, the applied voltage should not exceed 5V / cm.   (4) electrophoretic behavior of electrophoresis temperature DNA in agarose gel electrophoresis is not affected by the temperature of electrophoresis. The relative migration rate of DNA fragments of different sizes does not change significantly between 4 and 30 degrees, but gel with low concentration of 0.5% or low melting point gel is relatively weak, preferably at 4 degrees.   (5) dye embedded fluorescent dye ethidium bromide was used to detect DNA in agarose gel. The dye was embedded in the stacked base pairs and elongated and notched circular DNA, making it more rigid and reducing the linear mobility by 15%.   (6) The composition of ionic strength electrophoresis buffer and its ionic strength affect the mobility of DNA electrophoresis. In the absence of ions, such as misuse of distilled water to prepare gels, the conductivity is minimal and DNA hardly moves. In high ionic strength buffer (such as 10 x electrophoresis buffer), conductance is very high and obvious heat production.   Agarose gel electrophoresis is also commonly used in isolation and identification of nucleic acids, such as DNA identification, DNA restriction endonuclease map production, etc. Because of its convenient operation, simple equipment, small sample size and high resolution, this method has become one of the common experimental methods in genetic engineering research. Agarose gel electrophoresis kit contains 10 agarose preforms, high voltage fast electrophoresis solution 15mL, DNA loading buffer6x 200 L, scissors and user manuals, with 8 hole 6*6, 6 hole 6*6, 13 hole 6*12, 18 hole 6*12 and other specifications.
Latest company new about What advantages does carbomer 940 have as a pharmaceutical gel?
2021/02/03

What advantages does carbomer 940 have as a pharmaceutical gel?

For many people, especially women, a good skin condition is very important. Many skin topical medicaments contain a special component, Carbomer 940. Although this professional term sounds strange to us, its application to skin is very extensive, mainly due to the gel produced by carbomer 940 for skin. There are many advantages.   Some experts have prepared Allantoin Gel with 1.5% carbomer 940 to treat skin diseases such as dryness and psoriasis. The clinical results show that the gel has good compatibility with the skin, has a lasting effect and has no greasy and stuffy feeling on the skin. Amin and other erythromycin gel prepared by 1% carbomer 940 were used to treat acne. The results showed that the number of acne and basal diameter were significantly reduced.   carbomer gel   The ultrasonic diagnostic gel made by carbomer 940 has the advantages of no irritation to human skin, fine appearance, fine texture, no damage to the probe, no pollution, good lubrication, good viscosity and stable preparation. It has been proved by clinical practice that all the quality indicators achieve the desired effect.   In addition, the preparation of ketoprofen from 4 different substrates showed that the drug was released most rapidly from carbomer gel. The release rate was carbomer gel > hydrophilic ointment > cold cream > white vaseline. It suggested that carbomer could promote the transdermal absorption of drugs.   Carbomer 940 gel matrix has the advantages of simple operation, stable quality and no need of open flame heating compared with Vaseline matrix and cream substrate. It is especially suitable for the preparation of volatile drugs with poor thermal stability and small quantities of urgent drugs.   Desheng is a manufacturer specializing in the production and development of carbomer 940. Since its launch, cooperative enterprises have exceeded 100+. So many companies have chosen to cooperate with De Sheng to show that our products are better than those of other manufacturers. The gel matrix made from the raw product of Kam Sheng 940 has the characteristics of water-soluble matrix, quick release, no greasy, easy to spread, and skin. Mucous membrane is not irritant, welcome the manufacturers who have great demand to choose to cooperate with Desheng.
Latest company new about What are the applications of tris (77-86-1) as a PH regulator
2021/02/02

What are the applications of tris (77-86-1) as a PH regulator

If you want to ask which reagent in the biological buffer is the most widely used, then Tris is definitely the seeded player. Tris base (77-86-1) is white crystal particles under normal conditions, acid-base The indicator pH is 7-9. It is an important organic chemical raw material. It is most widely used as a pH regulator to maintain a stable pH in the reaction. However, many people do not know the specific application of pH adjustment. Let Desheng Xiaobian take you to find out!   Application of Tris(hydroxymethyl)aminomethane in eye drops   Eye drops are one of the most commonly used drug formulations for ophthalmological diseases. For many eye diseases, eye drops have a direct and rapid therapeutic effect. Due to the special anatomical and physiological characteristics of the eyes, corresponding requirements are put forward for ophthalmic preparations: the pH of normal tears is 7.2-7.4, and the range of pH tolerated by normal eyes is 5.0-9.0. The pH value of the eye drops will directly affect the eye irritation and the curative effect of the drug. When preparing eye drops, a buffer should be added to adjust the pH of the solution so that it is roughly similar to the tear fluid to reduce the impact on the eyes. Stimulus. Tris(hydroxymethyl)aminomethane is a commonly used pH regulator in eye drops.   Product packaging   Application of TRIS in nucleic acid detection   Nucleic acid testing is an important means to diagnose the new coronavirus. Tris is an additive in the virus preservation solution, the core material for nucleic acid testing. T can maintain the pH of the sample in the virus preservation solution and act as a biological buffer Effects: Viruses and their nucleic acids are more sensitive to environmental pH. Nucleic acids (DNA, RNA) are easily hydrolyzed in acidic solutions, and are more stable in neutral or weakly alkaline solutions. Its other function is to maintain the stability of the nucleic acid released after the lysis of the sample to be extracted to avoid degradation of the nucleic acid, increase the concentration and purity of the nucleic acid, and ensure the accuracy of subsequent nucleic acid detection and analysis operations.   Application of TRIS in cosmetics   You use various skin care products every day, but you don’t know that the commonly used PH regulator in skin care products is tris. PH regulator is actually a neutralizer. Everyone knows that everyone has different skin types. , The suitable cosmetics are also different. The ingredients in many cosmetics are very complex. If you want a suitable pH value, you must use TRIS to adjust, so that the entire raw material composition will not change too much, so that the cosmetics can be applied more gently on the face without irritation.   Desheng Technology is a professional manufacturer of biological buffers. TRIS is the company's advantage. The product has a purity of ≥99% and a high level, which can be used in many fields. Spot supply, the average daily output is ton-level, if you are interested, please click on the official website or call for consultation.
Latest company new about Research on Carbomer 980
2021/02/01

Research on Carbomer 980

  Carbomer, as an efficient thickening agent, suspending agent and gel matrix, has been widely used in cosmetics. Carbomer 900 series are polymer copolymers of acrylic acid and allyl sucrose or allyl pentaerythritol. According to the relative molecular weight and crosslinking degree of polymers, Carbomer can be divided into many different types. Carbomer 980 is one of carbomer series products.   Carbomer powder and gel   Related research:   The rheological properties and influencing factors of carbomer 980 were studied. The rheological properties of carbomer 980 were affected by various factors such as neutralization type, pH value, concentration, electrolyte and so on. The neutralization properties of carbomer 980 in different neutralization bases were different. Among them, Na0H neutralization carbomer 980 could change the viscosity of the gel in the neutralization process.   The viscosity of carbomer 980 gel is positively correlated with the concentration. The higher the concentration, the higher the viscosity of the gel. The initial pH value of Carbopol 98 with different concentrations before neutralization is different. The higher the concentration is, the lower the initial pH value is.   Carbomer 980 gel is sensitive to electrolyte ions. The presence of electrolyte makes the viscosity of carbomer 980 gel drop sharply, and the two valence ion has greater influence than monovalent ion. The decrease of viscosity of carbomer gel is mainly due to the reduction of the repulsive force of isoelectric charges on the main chain of polymer, thus reducing the actual effective concentration of carbomer in the system.   Different ions have different effects on the viscosity of carbomer gel, which is mainly related to the number of total charges of ions in the solution. The monovalent ions weaken the viscosity of carbomer gel by shielding the charge, resulting in the decrease of the viscosity of carbomer gel. Besides the action of the two valence ion, when the concentration is enough, it will precipitate with carbomer to form a salt substance, which will further affect the gel. The viscosity and transparency of the product.   The effect of 5 different electrolyte ions on the viscosity, pH value and turbidity of carbomer 980 gel was found to be basically the same. The results showed that the electrolyte had a certain correlation with the viscosity, pH value and turbidity of carbomer.   In this study, the rheological properties and influencing factors of carbomer 980 were studied. Because the viscosity of many cosmetics may affect the sensory characteristics of products, which directly affects the acceptance of products by consumers, how to control these rheological parameters becomes a decisive factor in the practical application of cosmetics formula. Different carbomer and appropriate concentration should be selected according to the actual demand of the formula, and the influence of various factors on carbomer system should be considered comprehensively.  
Latest company new about Desheng acridine ester NSP-DMAE-NHS sells well because of this
2021/02/01

Desheng acridine ester NSP-DMAE-NHS sells well because of this

The CAS number of NSP-DMAE-NHS is 194357-64-7, and the molecular formula is C30H26N2O9S. It is a luminescent substrate reagent used in chemiluminescence experiments. Its parent is an acridinium ester. Depending on the substitution group it contains Many derivatives with different characteristics, acridinium ester NSP-DMAE-NHS is one of the more commonly used ones.   There are a total of 6 acridinium ester products with different groups developed and produced by Desheng. Only the acridinium ester NSP-DMAE-NHS has the top sales volume. As long as the inventory is in stock, it will be cleared immediately. This month ends today. , Has been replenished three times but can be sold out in a short time each time. Such a rapid sales rate is indeed unexpected. Next, let's analyze the reasons for the rapid sales of Desheng NSP-DMAE-NHS.   1. Good product quality. Desheng NSP-DMAE-NHS is a golden yellow powder under normal conditions, with a very fine and bulky texture, a purity of more than 98% by HPLC method, no peculiar smell, and good market feedback. NSP-DMAE-NHS is very stable at pH 7.0, and this one adds its water solubility test, which can be performed in water in the detection of antigen nucleic acid. Compared with other acridine salts, acridine hydrazide, NSP-DMAE-NHS has better luminous efficiency     2. Sufficient inventory. This is a very big advantage. Maybe you can find a lot of manufacturer information when you search for NSP-DMAE-NHS manufacturers on the Internet, but when you really want to purchase, you will find that there is real stock In fact, there are very few manufacturers. Many purchasers have searched all the chemical platforms on the Internet and found that there are very few manufacturers with production and R&D capabilities. This will not happen in Desheng. Desheng has a professional R&D team, acridine The pyridine ester chemiluminescence products are all developed and produced by our company, and the inventory is sufficient.     3. The price is favorable and widely used. First of all, Desheng is a professional manufacturer of acridine esters, with a professional R&D and production team. The product quality is guaranteed and the price is relatively more favorable. Secondly, the conventional acridine esters are all with high quantum yield and luminous efficiency. It is higher than other luminescent reagents, has less interference, low background, and is easier to couple. The labeling is simple and stable, and the effect on luminescence performance after labeling is very small. This also makes NSP-DMAE-NHS widely used.   The acridinium ester NSP-DMAE-NHS developed and produced by Desheng is mostly used in other technologies such as chemiluminescence, high performance liquid chromatography, sensor technology and flow injection technology. Because it is in direct emission mode, the analysis speed is relatively fast. The required equipment is simpler than other luminescent reagents, and the sensitivity is very high. It can be widely used in chemical food safety, biomedicine, environmental testing and other fields.
Latest company new about What are the classification of nucleic acid test swab preservation solution
2021/01/31

What are the classification of nucleic acid test swab preservation solution

What is nucleic acid detection, that is, after collecting human secretions, under laboratory conditions, through the analysis of virus RNA gene sequence, using PCR amplification method for detection, clinical etiology diagnosis. At present, nucleic acid detection is the most effective method to determine whether the patient is infected with the virus as early as possible, and to detect and treat the virus as early as possible.   Nucleic acid test swabs are divided into two types: nasal swab and pharyngeal swab. During the sampling process, the doctor will use a swab like a cotton swab to wipe the secretion around the pharynx, tonsil or nasal cavity. As long as it is "gently wiped", it is quick and painless. Medical institutions will disinfect the test area, and medical staff will also disinfect their hands to avoid cross infection. Generally speaking, the sampling process is safe and clean, and there is no need to worry about the risk of infection. Two types of virus preservation solution of Desheng   So what are the types of swab preservation solution after sampling? Swab preservation solution can be divided into inactivated and non inactivated. At the beginning, almost all the swab preservation solutions used in the market are direct preservation of live virus, that is, non inactivated swab preservation solution. This preservation method will lead to higher infection risk for medical staff in sampling, transportation and detection. In view of this situation, anti epidemic measures should be taken It is very necessary to use the swab preservation solution to inactivate the virus directly, but it should be noted that: while inactivating the virus, we should also consider whether the preservation solution can stably preserve the integrity of the virus nucleic acid, so as to avoid the degradation of the nucleic acid in the sample before detection, resulting in the "false negative" of nucleic acid detection. The inactivated virus preservation solution produced and developed by Desheng can avoid this problem.   In short, nucleic acid detection swab preservation solution can be divided into two categories. The inactivated swab preservation solution produced and developed by Desheng is a swab preservation solution with cleavage function, which contains cleavage salt of inactivated virus and cleavage protein to protect nucleic acid. Virus preservation and cleavage are completed in one step, and the other is a non inactivated swab preservation solution. On the contrary, it can protect the integrity of virus protein and nucleic acid In addition to nucleic acid detection, it can also be used for virus culture research. The operating environment requirements of the two preservation solutions are not the same. The inactivated environment does not need to be so strict, while the non inactivated environment will have higher requirements because of the risk of virus infection.
Latest company new about Professional manufacturer of chemiluminescence reagent acridinium ester-Desheng
2021/01/30

Professional manufacturer of chemiluminescence reagent acridinium ester-Desheng

When it comes to chemiluminescence, among many luminescence systems, the earliest chemiluminescence phenomenon is actually found in organisms, such as fireflies. By the end of the 19th century, people discovered that simple non-biological organic compounds can also produce chemiluminescence. For example, Lofen base (2,4,5-triphenylimidazole) can emit green light when oxidized by hydrogen peroxide and other reagents in alkaline medium. After that, the analysis of chemiluminescence reagents for acridinium ester derivatives became the 20th century. A popular research content in the 1980s, more and more luminescence reagent manufacturers prefer the use of acridinium esters, and the pace of domestic research is not far behind. Acridine ester chemiluminescence systems are widely used in various inorganic and organic compounds, biological and pharmaceutical analysis fields due to the advantages of no catalyst, mild reaction conditions, and good reproducibility.   However, there are not many manufacturers of acridine esters in China, and there are few good manufacturers. Desheng can keep up with the market development direction and develop acridine ester products that satisfy customers. It is really commendable. A strong scientific research team, strict quality inspection department, and a dedicated chemical reagent luminescence laboratory in a dust-free and sterile environment provide a solid guarantee for the quality of the products. Chemiluminescent acridinium ester There are actually 8 different series of acridinium esters, such as acridinium ester DMAE-NHS, acridinium ester NSP-DMAE-NHS, acridinium salt NSP-SA, acridinium hydrazide NSP-SA-ADH, etc., although they all Acridine ring, but the tested substances are different, and the acridine series used will be completely different. Many buyers often need to purchase three or more different series of acridine esters when purchasing. After asking many manufacturers, It is found that the production capacity of many manufacturers is far from enough, but Desheng will not have this kind of problem, not only the variety is complete, but also the inventory is sufficient. Wuhan Desheng is a professional manufacturer of chemiluminescence reagents. There are not only the above 8 series of chemiluminescence reagents, but also other chemiluminescence products such as luminol and isoluminol, which can fully meet the needs of manufacturers. Compared with other manufacturers, Desheng’s acridine ester products have the characteristics of fast luminescence reaction, high sensitivity and strong stability. Desheng has always been at the forefront of chemiluminescence reagents, and obtained with high-quality quality and good technical services. Has been widely recognized by the industry.
Latest company new about What are the advantages of acridine esters compared with other chemiluminescent reagents
2021/01/30

What are the advantages of acridine esters compared with other chemiluminescent reagents

Chemiluminescence immunoassay is currently the most advantageous immunoassay method. The core reagent is the chemiluminescence substrate. For example, the peroxidase substrate luminol and the alkaline phosphatase substrate AMPPD are widely used. There are acridine ester chemiluminescence reagents, which can directly generate chemiluminescence without enzyme catalysis.   Compared with chemiluminescence substrates such as luminol or alkaline phosphatase, acridine ester chemiluminescence reagents have obvious advantages. Its luminescence reaction does not require enzyme catalysis, and the luminescence detection step is simple and easy to automate; and In terms of sensitivity, acridine esters are many times higher than luminol and peroxyoxalate, and can detect a smaller amount and a wider range of detection indicators. Therefore, acridine ester chemiluminescent substrates are also more advanced immunoassay reagents.   What are the advantages of acridine esters compared with other chemiluminescent reagents   Acridine esters have a higher quantum yield. Compared with luminol, its chemiluminescence efficiency is five times or more than that of luminol; secondly, the properties of acridinium esters are more stable, and are affected by other substances in the reaction system. The impact is also smaller and storage is convenient. Thirdly, the chemiluminescence process of acridinium ester has a fast reaction speed, which can cause luminescence in the presence of hydrogen peroxide or other peroxides. The characteristics of the chemiluminescence reaction mechanism of acridinium esters show that the effect of light quenching is small, and the dissociation of the luminescent group and the luminous efficiency during the reaction will not be affected by the length of the connecting arm.   Acridinium esters and their derivatives can realize the chemiluminescence analysis of biological macromolecules such as antigens, antibodies and DNA, and are a kind of excellent chemiluminescence immunoassay labeling reagent. The main principle of action is to mark these biological macromolecules by directly or indirectly interacting with the amino, carboxyl or phosphoric acid groups on the biological macromolecules through the unique substituent groups on the molecular structure.   Among the many chemiluminescence reagents, the price of acridine esters is also the highest, but Desheng still provides luminol, isoluminol and other types of chemiluminescence reagents, which can meet the needs of different experimental detections. The luminescent reagent is not the most advanced, but the appropriate one.
Latest company new about Carbomer reserve price promotion
2021/01/29

Carbomer reserve price promotion

The only difference with imported brands is the price. The spot price of Desun Carbomer is as low as 100 yuan/kg, and the quantity is limited, so I missed waiting for the next batch. It is used for cosmetic raw materials, pharmaceutical gels, hand-washing gels, etc. For details, please contact Desheng website or the phone number reserved on this website. Desun has been committed to the research of polyacrylic acid. In addition to creating serum separation gel series, the carbomer series is also a long-made series. With 15 years of R&D and production experience, Desun carbomer products are more trustworthy! Carbomer powder   Carbomer products were first produced abroad, and now a foreign brand controls more than 80% of the market. The reason for this situation is nothing more than the gap in technical capabilities. After continuous research and development efforts in recent years, Desheng has finally been able to In some of these types, we have achieved the situation of "people do not have me, others have me superior", but after all, they are still lacking in reputation. The price increase is also to expand the reputation, win by quantity, and hope more customers Be able to know Desheng. Desheng proposes that Carbomer products are offered at the lowest price, with the best product quality assurance, free samples, and perfect after-sales service. If you have any questions, you can contact a professional one-to-one sales manager for full-time service, and for product problems, technical participation in the whole process , You understand, we communicate with each other, we understand what you don’t understand, we teach! carbomer powder As a widely used carbomer product, retail and wholesale, small quantities and large quantities, Desheng are very welcome, and hope that all partners can take time to visit the factory, so as to facilitate further cooperation and win-win in the future. The regular guarantee of Desun Carbomer is 10kg/bag. According to customer requirements, product indicators can also be customized and special packaging requirements can be subpackaged. According to market price changes, this price will also increase or decrease according to the needs of each customer. Please ask all friends who need Carbomer to call for consultation. It is also very good to add a standby raw material supplier!
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