China Wuhan Desheng Biochemical Technology Co., Ltd Company News

I believe that everyone must have had such experience. When going to the hospital for medical treatment or routine medical examination, sometimes the doctor will ask you to do a blood test and a complete biochemical examination. In fact, the clinical biochemical detection mentioned here refers to studying the biochemical changes under the pathological state on the basis of the normal metabolism of the human body, by analyzing the changes of related metabolites in the body, looking for characteristic markers, establishing corresponding detection methods for disease prevention , Diagnosis, treatment and prognosis to provide biochemical information and decision-making basis. Furthermore, biochemical diagnosis refers to an in vitro diagnostic method that uses Lamber-Beer's law to measure various biochemical indexes of various inorganic elements, proteins, and non-protein nitrogen and enzymes, sugar, and lipids in vitro through various biochemical reactions. Liver function, kidney function, blood sugar, blood lipids and other inspection items belong to the biochemical diagnosis. Clinical biochemical diagnostic reagents and biochemical analyzers are used in combination, and the relevant technical principles of chemistry, enzymes, immunology, etc. are applied to diagnose clinical biochemical indicators related to the human body. Through the specific reaction between the reagent and the related analyte, a specific optical signal is given, which is recorded by the biochemical analyzer and compared with the calibrator to give the level of the related analyte. Biochemical diagnosis is one of the most commonly used in vitro diagnostic methods at present, and it is also the earliest and most mature IVD subdivision field developed at home and abroad. Among them, Trinder's reaction is a routine biochemical detection project catalyzed by a specific substrate oxidase. The oxidase catalyzes the substrate to produce hydrogen peroxide (H202). In the presence of phenol and 4-aminoantipyrine, hydrogen peroxide Peroxidase catalyzes the production of quinone compounds and water, which reflects the amount of hydrogen peroxide produced by the coloration of the quinone compounds, and indirectly detects a certain substrate concentration or a certain oxidase activity. Among the new Trinder's reagents, TOOS is the most commonly used because of its high water solubility, high molar absorbance (that is, more sensitive color reaction), color reaction intensity and fading. TOOS produced by Desheng is favored by more than 100 manufacturers because of its crystal morphology, high crystal purity, and pure white crystal color (important for this color reaction). The following are the relevant indicators of TOOS, please refer to it. TOOS   Product description TOOS is a new type of high water-soluble aniline derivative, widely used in diagnostic tests and biochemical tests. molecular weight 295.33 Molecular forluma C12H18NNaO4S Chemical structure CAS No. 82692-93-1 purity ≥99.5% SMILES O=S(CC(O)CN(CC)C1=CC=CC(C)=C1)([O-])=O.[Na+] Packaging details 10g/bottle；50g/bottle Transpotation conditions Room temperature（20℃-25℃） Storage conditions powder -20°C 3 years 4°C 2 years solution -80°C 6 months -20°C 1 month   remarks In Vitro: DMSO : ≥ 47 mg/mL (159.14 mM) *"≥"means soluble and does not represent saturation.   As a domestic senior manufacturer specializing in blood test reagents for 15 years, Desheng is committed to providing raw materials to help accurate diagnosis and treatment. Its TOOS products have been evaluated by more than 100 professional manufacturers in the industry and received numerous praises. If you are interested, please call to consult!

Many customers who purchase lithium heparin are facing a problem. They inquire from many lithium heparin manufacturers. In order to reduce procurement costs, they often choose the lower price manufacturer. After receiving the goods, they find that the product quality is not guaranteed at all. Must look at the cost performance. Buying products that do not meet the test requirements at a low price is a waste of manpower, material resources, and financial resources. Wise people know that it is impossible to buy really good products at a low price. The heparin produced by Desheng Lithium is a very reliable choice. Lithium heparin not only has a variety of potency for its choice, but the price is also worthy of that quality. Really achieve high efficiency and price ratio, high quality and high guarantee. Desheng always believes that quality is the prerequisite for everything. Only good products can be repeatedly purchased by customers. Some issues that need to be paid attention to when purchasing lithium heparin, 1. In order to ensure adequate blood anticoagulation, the heparin lithium anticoagulant test tube must be reversed and mixed 5-8 times as soon as possible after blood collection, especially when the blood collection temperature is higher than 25 ℃, the blood and lithium heparin must be mixed in time and Otherwise, it may easily lead to blood clotting or local clotting. 2. Lithium heparin anticoagulation is not irreversible anticoagulation, so the test should be completed within 6 hours after the blood collection of the heparin lithium anticoagulation test tube, otherwise it may cause errors in the test results. The dosage of lithium heparin should ensure that the specimen is fully and partially anticoagulated, so that most of the plasma indicators can be repeated within 6 hours, especially sensitive indicators such as AST, ALT, TBIL, DBIL, and GGT. 3. Lithium heparin can be used together with the separation gel. The anticoagulation effect, tube wall siliconization, centrifugal conditions, separation gel quality, etc. will affect the blood separation effect. It is recommended to use with the blood separation gel produced by our company to obtain high-quality plasma specimens. Recommendation for irradiation sterilization after adding to blood collection tube: use γ-ray irradiation, the dose is 8-25kGy. The irradiation dose can be determined by the initial colony number. The lithium heparin product developed by Desheng has the characteristics of customizable potency. The conventional one is 160IU / mg, but it can be adjusted according to customer needs. 150IU / mg, 170IU / mg, 180IU / mg, the higher the potency, the price It will also change with it. Desheng's lithium heparin product has higher purity than other companies, and the appearance is pure white. It can be seen directly by the naked eye that there are no foreign substances in other magazines, and the price is also higher than other products. Manufacturers are more favorable, and products are sold all over the country. Desheng is the first choice for purchasing lithium heparin products.    

Heparin is a blood anticoagulant commonly used in vacuum blood collection tube. Heparin anticoagulant is usually its sodium, potassium, lithium, ammonium salts, such as sodium heparin, lithium heparin, etc., among which lithium heparin is the best. The appearance of the finished lithium heparin is white to almost white powder, odorless, soluble in water and hygroscopic. According to the study, there was no significant difference in the results of TP, ASO, UA, ALT, Mg, Cl, TC and CRP between lithium heparin anticoagulant plasma and serum (P > 0.05). There were significant differences in the results of HBD, LDH and TBA between lithium heparin anticoagulant plasma and serum (P < 0.05). Therefore, except for HBD, LDH and TBA, the correlation between lithium heparin anticoagulant plasma and serum is good. Therefore, it is feasible to replace serum with lithium heparin anticoagulant plasma in life detection, which can be used as an important detection method. [Scope of Application] 1. The product is suitable for blood sample collection and anticoagulation in clinical biochemical examination and emergency biochemical examination, and also for blood sample collection and anticoagulation in some hemorheology projects. 2. Lithium heparin is recommended as an anticoagulant when determining ionic content in blood in clinical tests, because it is least likely to interfere with the determination of other ions. 3. This product is not a drug and cannot be used as an injection. Direct injection into human body and animals is prohibited. [Precautions] Heparin salt test tube must be inverted and mixed 5-8 times as soon as possible after blood collection. Heparin anticoagulation is not irreversible anticoagulation, so the lithium heparin test tube should be completed within 6 hours after blood collection. 3. Heparin may be involved in the metabolism of cellular enzymes and ions, and the amount of heparin additive should ensure adequate anticoagulation of all and local specimens, especially sensitive indicators such as AST, ALT, TBIL, DBIL and GGT. 4. Lithium heparin can be used with separation gel at the same time. Anticoagulation effect, wall silicification, centrifugation conditions, separation gel quality, etc. will affect the blood separation effect. It is suggested to cooperate with the serum separation gel produced by our company. 5. Suggestions on Sterilization: use γ irradiation at a dose of 8-25 kGy. De Sheng's lithium heparin potency is ≥ 150 IU/mg and anhydrous potency is≥160 IU/mg) are controlled with reference to the standard of sodium heparin API. The lithium heparin aqueous solution can be sealed and stored at 0-4℃ in a sterile state, and should be disposed and used up as soon as possible. Its maximum shelf life should not exceed 7 days,  

[Product name]Virus Transport Media [Packaging specifications]1L/bottle、5L/bottle [Product performance] Non-inactivated type: it does not contain lysate, which can maintain the activity and integrity of pathogen, and can be used for virus culture and isolation. Inactivated type: it can split pathogen instantly and release nucleic acid, and the protective agent can prevent nucleic acid from degradation. [Scope of use] The Virus Transport Media can be used for the collection, preservation and transportation of nasopharyngeal pathogen specimens such as new coronavirus, influenza, bird flu, hand-foot-mouth disease, measles and so on. Non-inactivated type: On the basis of Hank's, BSA (bovine serum albumin) amino acids, vitamins and other nutrients are added to maintain the virus' activity over a wide temperature range and maintain the originality of the sample to the greatest extent and can be used for virus nucleic acid extraction and detection, virus culture and isolation. Inactivated type: By fully mixing the collected samples with virus lysate and virus nucleic acid preservation solution, the virus in the samples can be inactivated, and the integrity of virus nucleic acid in the samples can be effectively guaranteed. The collected samples can be transported and preserved for a long time under normal temperature. The preserved viral RNA samples can be widely used for genetic testing, enzyme-linked immunoassay (ELISA), PCR testing, ect. [Storage conditions and time] Non-inactivated type: Store at 4-25 ℃. It shall be transported to the laboratory within 48 hours under 2-8 ℃ after sampling, or stored under - 70 ℃. Inactivated type: 30 days at normal temperature

In biochemical experiments or tests, almost all reactions need to be controlled within a certain pH range, especially those involving enzymes. PH changes have a greater impact on the reaction, so biological buffers are used to maintain the pH value of the reaction environment. In biochemical experiments, many of them simulate the detection reaction in the organism, which also requires high pH. Biological body is regulated by humoral fluid, so biological buffer is needed in the experiment. There are many types of biological buffer, and the preparation methods are somewhat different, but the principle is generally the same. Sodium hydroxide is usually added to the conjugate acid or hydrochloric acid is added to the conjugate base. Both methods can form a buffer solution with sufficient concentration of conjugate acid-base pairs. Here is the preparation method of a small amount (about 1-2l) of dihydroxyethylglycine Bicine or hydroxyethylpiperazine propionic acid EPPS:   Preparation of Bicine buffer   (1) 0.1M solution (A): Bicine 16.317g/ deionized water 1,000ml   (2) 0.1m NaOH solution (B):NaOH 4g/ deionized water 1,000ml   (3) the pH 5.1 1000 ml + 0 ml (B) (A) (A) : (B) = 5-0   PH 7.8 + 200 ml 1000 ml (A) (B) (A) : (B) = 5 to 1   PH 8.2 + 400 ml 1000 ml (A) (B) (A) : (B) = 5-2   PH 8.6 + 600 ml 1000 ml (A) (B) (A) : (B) = o   PH 10.4 + 800 ml 1000 ml (A) (B) (A) : (B) = five   Preparation of EPPS buffer   (1) 0.1M solution (A): EPPS 25.233g/ deionized water 1,000ml   (2) 0.1m NaOH solution (B):NaOH 4g/ deionized water 1,000ml   (3) the pH 5.2 1000 ml + 0 ml (B) (A) (A) : (B) = 5-0   PH 7.3 + 200 ml 1000 ml (A) (B) (A) : (B) = 5 to 1   PH 7.8 + 400 ml 1000 ml (A) (B) (A) : (B) = 5-2   PH 8.2 + 600 ml 1000 ml (A) (B) (A) : (B) = o   PH 8.8 + 800 ml 1000 ml (A) (B) (A) : (B) = five     It should be noted that: the preparation temperature is controlled at 20 degrees. If accurate pH value is needed, it can be measured with A pH meter, and then the proportion of solution A and solution B can be adjusted to A specific pH value. If it is necessary to exclude sodium ions in the test environment, it is also possible to replace sodium hydroxide with potassium hydroxide and change the weight according to the corresponding molecular weight.   DE sheng technology since the 05 years began to research and development production of separation, heparin, EDTA potash mining vessel additives, and in vitro diagnostic reagent, the color of the original substrate TOOS, MAOS new Trinder 's reagent, Bicine and Tris biological buffer and luminol, acridine esters such as chemiluminescence reagent has a deep research, in the independent research and development and synthesis of professional advantage.

  A lot of people know that the blood coagulant we produce is a suspending agent, which needs to be shaken before use. Is this of poor quality or can it not be shaken? The answer is: it needs to be shaken. The coagulant is different from our anticoagulants, such as EDTA dipotassium and heparin. The specific need is from its state characteristics. Different from the anticoagulants such as EDTA dipotassium, heparin and sodium citrate, the coagulant is not a solution, but a suspension, also known as a suspension. The reason why the anticoagulant is a solution state is that EDTA dipotassium and heparin are soluble in water, which exists in the size of molecules or ions in the water, and some components of the coagulant are insoluble in water, which is stored in small solid particles Yes. This is very similar to the muddy lime water, because the calcium hydroxide is slightly soluble in the water, a large number of small solid particles of calcium hydroxide are suspended in the water, forming a suspension.   Solution or suspension is essentially the dispersion system of mixture, and the dispersion phase is dispersed in the dispersion medium. Dispersion system is often called uniform single-phase solution, heterogeneous multi-phase colloid and coarse dispersion system suspension and emulsion with particle size more than one micron. Emulsion is similar to suspension except that the dispersed phase is liquid. Therefore, all suspensions are of large particle size. The coagulant components of the dispersed phase are insoluble in the dispersing medium such as alcohol, but for the naked eye, the particles are relatively small, and precipitation or stratification will occur after placement. Under the condition of carbon dioxide isolation, the turbid lime water will be slowly clarified after a long time of standing. Then our coagulant suspension will be gradually clarified from the upper layer after standing for a long time, so it is necessary to shake it well before use. It is worth noting that although the problem of long-term sedimentation of blood coagulant suspension is not the main quality problem of coagulant, but for the convenience of use, there are still differences. The coagulant newly developed by Desheng has made a great improvement in this aspect. Compared with the previous coagulant, in addition to the improvement of blood coagulation effect and speed, it is smaller in particle size, although long-term sedimentation is also possible, However, the time of long-term precipitation is greatly prolonged, and the suspension can be shaken into uniform suspension only by slight shaking.

There are two kinds of blood anticoagulant heparin salt produced by us, namely heparin sodium and heparin lithium. This is because heparin lithium is made from heparin sodium, which can only be worthwhile by conducting cation exchange with heparin sodium through ion exchange resin. Here is a brief introduction to the preparation process and the main equipment used. The preparation of heparin lithium in foreign countries is usually made with high-quality heparin sodium as the raw material, which has a high raw material cost, and the ion exchange link is carried out under the condition of strong acid pH1.5 and low temperature, resulting in high titer loss, low yield and high production cost. In China, the preparation of heparin lithium has been greatly improved according to the above problems. The crude heparin sodium is directly used as the raw material, and after enzymatic hydrolysis by heparin enzyme, deproteinization, decolorization by hydrogen peroxide oxidation, and multiple alcohol-precipitation steps, lithium chloride is added to conduct cation exchange through cation exchange resin, which is worthy of high-quality heparin lithium. This method greatly saves the cost of raw materials and production costs. In the preparation of heparin lithium, the exchange of sodium ions into lithium ions by cation exchange resin is the core step. Ion-exchange resin refers to the polymer compound with the active group that can adsorb ions, which has network structure and is insoluble. Its full name consists of classification name, skeleton name and basic name. Pore structure is divided into gel type and large pore type, properties are divided into strong acid cationic resin, weak acid cationic resin, strong basic anion resin, weak basic anion resin, in addition to the basic type of chelation, amphoteric, oxidation reducibility. Resin matrix manufacturing raw materials are mainly styrene and acrylic acid and divinylbenzene polymerization resin of two categories. In the use of reagents, sometimes do not use cation or anion to exchange resin hydrogen ions or hydroxide ions, grams to avoid the solution pH changes caused by the impact. For example, in the preparation of heparin lithium, lithium chloride is now used to exchange the hydrogen in the ion exchange resin, and the lithium ion resin is used to exchange the sodium in the heparin sodium, so that the heparin lithium is worth; Resin is regenerated not by acid, but by lithium chloride. Different resins have different adsorption rules for ions. Generally speaking, high-priced ions are adsorbed by some, while those with large diameter of isovalent ions are preferentially adsorbed. DE sheng technology since the 05 years began to research and development production of separation, heparin, EDTA potash mining vessel additives, and in vitro diagnostic reagent, the color of the original substrate TOOS, MAOS new Trinder 's reagent, Bicine and Tris biological buffer and luminol, acridine esters such as chemiluminescence reagent has a deep research, in the independent research and development and synthesis of professional advantage.

Founded in 2005, wuhan desheng technology co., ltd. is a company specializing in the research, development, production and sales of blood test reagent. The company focuses on the blood test reagent industry. Is a professional research and development, production, sales of blood test reagent institutions. Since its establishment, the company has been abiding by and adhering to the core business philosophy of "taking morality as the foundation and honesty as the first", and has taken it as our duty to provide value to customers, which has been well received by customers. The success of desheng technology today is inseparable from the efforts and dedication of the founder and chairman wang zhongxi.     Wang zhongxi, the son of a shaanxi farmer, used to be an employee of a state-owned enterprise. He used to have an iron rice bowl, and it was easy for him to live a safe life. This unusual path has been followed for 10 years. Through continuous exploration and innovation, he finally went to the sea to do it by himself, and picked up his own specialty, the study of serum separation glue, at first he and his wife bought a computer. You can imagine how computer phones are more than 10 years ago is not very common, in order to more quickly into the product research and development, not typing he consult others, learning pinyin typing, learn how to use the Internet, check literature data check until midnight every day, no professional stir bar, stirring with a glass rod, no dryer, use something else instead of their own way to drying, the final product to take a test, the products are qualified! The moment he got the certificate, wang felt it was all worth it.   With the success of the research and development of serum separation glue, other vascular additives such as dipotassium, tripotassium, heparin sodium, heparin lithium and other products have been produced, many products are exported to foreign countries, such as Russia, India, Turkey, Brazil, the United States, Sweden have reached a long-term cooperative relationship. The company's annual sales in 20 million yuan, more than 400 customers at home and abroad. The company's products and services are widely recognized and affirmed by customers at home and abroad. It has become the preferred service provider and supplier for customers in the industry. The market develops at a rate of about 20% every year.   Any enterprise want to be stronger, is not an easy thing, the development of DE sheng road is never plain sailing, when making the separation of rubber products in the packaging before a little problem, corporate responsibility, sincerely apologize to the customer, the company to the production of products strictly, keep improving, keep on process, equipment, environment, raw materials continue to improve, strengthen the quality consciousness and skills training for personnel education, ensure the stability of product quality and consistency, finally survive, fully explain the incident in the products have problems, DE sheng, never shirk responsibility, Honesty is the foundation for an enterprise to grow bigger and stronger. The enterprise culture of DE sheng: take morality as the foundation, take honesty as the first, quality as the first, technology as the first, take customers as the first, symbiosis and win-win, open up and innovation, and pursue excellence. The company is named DE sheng, the original intention is also so, try to ask how such enterprises can not produce better and more professional products.   Even now, it's almost 60 years old, he had no boss's shelves, and often help to see him in the production workshop production 2 k, 3 k, separation of plastic products such as, one day he came from 2 PM to 6 PM, is not only a technological or physical one thing, for our young people are not necessarily can insist so long, is there a few entrepreneurs under the company scale is bigger and bigger also can to help make the product at the grassroots level and work overtime to do, I don't think he must be just for the money, this kind of behavior model is a kind of spirit, a kind of indomitable spirit, in his view, It must be done with high quality and high efficiency. All employees of the company can see his efforts and realize the value of this spirit.   I hope everyone can learn from Mr. Wang's entrepreneurial spirit. Under the leadership of such an entrepreneur, desheng technology will surely make better and more professional products, become a leader in the industry, aspire to become the world's leading brand in the industry, and make contributions to the cause of human health. At present, the company has established long-term cooperative relations with many large enterprises. We also welcome them to visit our company to visit the separation glue and other products, laying the foundation for further cooperation in the future.

Founded in 2005, wuhan desheng technology co., ltd. is a company specializing in the research, development, production and sales of blood test reagent. The company focuses on the blood test reagent industry. Is a professional research and development, production, sales of blood test reagent institutions. Since its establishment, the company has been abiding by and adhering to the core business philosophy of "taking morality as the foundation and honesty as the first", and has taken it as our duty to provide value to customers, which has been well received by customers. The success of desheng technology today is inseparable from the efforts and dedication of the founder and chairman wang zhongxi.     Wang zhongxi, the son of a shaanxi farmer, used to be an employee of a state-owned enterprise. He used to have an iron rice bowl, and it was easy for him to live a safe life. This unusual path has been followed for 10 years. Through continuous exploration and innovation, he finally went to the sea to do it by himself, and picked up his own specialty, the study of serum separation glue, at first he and his wife bought a computer. You can imagine how computer phones are more than 10 years ago is not very common, in order to more quickly into the product research and development, not typing he consult others, learning pinyin typing, learn how to use the Internet, check literature data check until midnight every day, no professional stir bar, stirring with a glass rod, no dryer, use something else instead of their own way to drying, the final product to take a test, the products are qualified! The moment he got the certificate, wang felt it was all worth it.   With the success of the research and development of serum separation glue, other vascular additives such as dipotassium, tripotassium, heparin sodium, heparin lithium and other products have been produced, many products are exported to foreign countries, such as Russia, India, Turkey, Brazil, the United States, Sweden have reached a long-term cooperative relationship. The company's annual sales in 20 million yuan, more than 400 customers at home and abroad. The company's products and services are widely recognized and affirmed by customers at home and abroad. It has become the preferred service provider and supplier for customers in the industry. The market develops at a rate of about 20% every year.   Any enterprise want to be stronger, is not an easy thing, the development of DE sheng road is never plain sailing, when making the separation of rubber products in the packaging before a little problem, corporate responsibility, sincerely apologize to the customer, the company to the production of products strictly, keep improving, keep on process, equipment, environment, raw materials continue to improve, strengthen the quality consciousness and skills training for personnel education, ensure the stability of product quality and consistency, finally survive, fully explain the incident in the products have problems, DE sheng, never shirk responsibility, Honesty is the foundation for an enterprise to grow bigger and stronger. The enterprise culture of DE sheng: take morality as the foundation, take honesty as the first, quality as the first, technology as the first, take customers as the first, symbiosis and win-win, open up and innovation, and pursue excellence. The company is named DE sheng, the original intention is also so, try to ask how such enterprises can not produce better and more professional products.   Even now, it's almost 60 years old, he had no boss's shelves, and often help to see him in the production workshop production 2 k, 3 k, separation of plastic products such as, one day he came from 2 PM to 6 PM, is not only a technological or physical one thing, for our young people are not necessarily can insist so long, is there a few entrepreneurs under the company scale is bigger and bigger also can to help make the product at the grassroots level and work overtime to do, I don't think he must be just for the money, this kind of behavior model is a kind of spirit, a kind of indomitable spirit, in his view, It must be done with high quality and high efficiency. All employees of the company can see his efforts and realize the value of this spirit.   I hope everyone can learn from Mr. Wang's entrepreneurial spirit. Under the leadership of such an entrepreneur, desheng technology will surely make better and more professional products, become a leader in the industry, aspire to become the world's leading brand in the industry, and make contributions to the cause of human health. At present, the company has established long-term cooperative relations with many large enterprises. We also welcome them to visit our company to visit the separation glue and other products, laying the foundation for further cooperation in the future.

In recent years, in vitro diagnosis (IVD) has been developing rapidly in China, with a domestic market capacity of 70 billion yuan and an average annual growth rate of nearly 20% in five years. IVD has become the largest and fastest growing segment of the whole medical device market. Since its establishment in 2005, desheng technology has only used vasculture-related reagents. Later, it has gradually developed in vitro diagnostic materials such as chromogenic substrate, biological buffer and chemical luminescence agent. With the rise of domestic in vitro diagnosis manufacturers, raw material companies in recent years showed a rapid development trend. There were only 23 raw material companies founded before 2010, and as many as 44 in 2010 and beyond. In the three years from 2016 to 2018, more than 17 new raw material companies were established, an average of 6 a year. Domestic IVD raw material competition is intense.     By city, Beijing leads the pack, accounting for more than a quarter of the total. Hangzhou, shenzhen and wuhan are in the second tier. The other 34 are widely distributed across the country. Similar to the distribution of chemiluminescence manufacturers, the raw material manufacturers are also distributed in the southeast region centered in Beijing, Shanghai, guangzhou-shenzhen, while only chongqing and chengdu are slightly distributed in the central and western regions. However, at the same time, with the gradually intensified competition in the IVD terminal market, the war of IVD has also been led to the upstream raw material field. China's IVD raw material industry is also facing an embarrassing position similar to the chip in IT. Many IVD manufacturers have the experience of ordering imported raw materials from unconventional channels (Europe, America or Japan). The reason is that the core raw materials are monopolized by these import manufacturers. IVD manufacturers in China are in a very weak position in the price negotiation, and the phenomenon of being controlled by others is very obvious. Of course, domestic reagent also presents the trend of gradually replacing imported reagent. More and more enterprises begin to use domestic reagent raw materials. DE sheng technology since the 05 years began to research and development production of separation, heparin, EDTA potash mining vessel additives, and in vitro diagnostic reagent, the color of the original substrate TOOS, MAOS new Trinder 's reagent, Bicine and Tris biological buffer and luminol, acridine esters such as chemiluminescence reagent has a deep research, in the independent research and development and synthesis of professional advantage.

Generally to the hospital, say nothing, the doctor will let you do a blood test, check whether there is a problem with blood. Why is blood test so important and common? What does it know about the body? How to read the blood routine report without a doctor? Mo Ji, Wuhan Desheng biochemical technology specialized in the production of in vitro diagnostic reagents for 12 years, let you read this article, absolutely understand! Key points of this paper: ·Why does the doctor always ask me to check the blood? ·What's in the blood? ·What index should blood routine check? ·What is the significance of changes in indicators? The continuous circulation of blood in the human body plays an important role in ensuring the balance of metabolism, environment and function regulation. Pathological changes of any components in the blood will affect the tissues and organs of all parts of the body. On the contrary, pathological changes of organs or tissues will also cause changes in blood composition to a large extent. In addition, checking the change of blood composition can also find the cause of disease for treatment, which is helpful for doctors to judge correctly. In the past, children had a cold. They went to the hospital directly to hang liquid medicine. As a result, many times they took medicine. The cold was not good. Now it's different. To go to the hospital, you need to take a blood sample first to determine whether the cold is caused by a virus or a bacterium. Then the doctor diagnosed and treated according to the results of blood test, the effect was naturally good. Therefore, the significance of blood test should not be underestimated. Why to draw a little blood, can know the body each part has what unusual? Before you answer this question, you need to know what's in your blood.

Application of luminol in chemiluminescence analysis Luminol chemiluminescence analysis has the advantages of high sensitivity, wide linear range, fast analysis speed and relatively simple instrument equipment. It is widely used in the fields of life science, environmental science, clinical medicine and physiology. Chemiluminescence analysis in addition to many efficient separation methods such as combination of high performance liquid chromatography (HPLC), capillary electrophoresis, etc, in recent years, it also and flow injection analysis, electrochemical analysis reagent, biological immune analysis, immobilized technology, sensor technology, analysis technology, the rapid development, become one of the hotspots in the field of chemical analysis. Luminol has become one of the most widely used chemiluminescence reagents due to its advantages of high quantum yield, easy synthesis and good water solubility. Zhang zhujun et al. made a detailed review on luminol chemiluminescence reaction and its application in analysis. The analytical application of luminol - iodide chemiluminescence system is introduced. However, due to the slow reaction rate of luminol oxidation luminescence, it is necessary to add some enzymes or inorganic catalysts. The detection of analyte by luminol chemiluminescence and reagent immobilization is an important research direction. A chemiluminescence sensor for the determination and measurement of glucose was designed by using a light-emitting system, which was fixed on the carrier. A sensor for the determination of riboflavin and rutin was designed based on a similar method. A time - resolved chemiluminescence analysis method for the determination of homobarine and homobarine in binary mixtures was proposed based on the different catalytic rates of peroxidase to the oxidation of the amine compounds. Due to the stable performance and low price of luminol, practical application research and analysis will have a broader application prospect. Another major use of chemiluminescence in immunoassay is immunoassay. Chemiluminescence immunity in which a luminescent reagent or sensitizer molecule is labeled on an antigen or antibody for enzymatic, antigen, or antibody determination. Application of luminol in organics analysis The organic compounds can be analyzed and determined by the promotion and inhibition of luminol luminescence system. Recently, the inhibitory effects of different antioxidants on superoxide anion expansion, radical transradical, peroxynitrite and luminescence of luminol were systematically investigated. The free radical scavengers in plant extracts were determined based on the inhibition of the antioxidant system and in combination with the technique. A new method for the determination of hemorazine and hemorazine has been developed based on the properties of the potential antioxidant hemorazine, which promotes the yao 10 system, and the glutorazine has an inhibitory effect on the fumino nitrite system. Based on the promotion of a luminescence reaction, the chemiluminescence method for the determination of isopropyl throat, chloropropyl throat, vanilla amygdalic acid, isosmoke well and skin was established based on the inhibition of the system. Based on the properties of peroxide dismutase inhibiting luminol superoxide anion chemiluminescence, xu et al. established a simple method for determination. The content of penicillin 1 in human serum was determined based on the promotion effect of penicillin 1-10 system and the high-efficiency head-on analysis technique. Based on the inhibition effect of the system, theanine in tea was determined with the linear range of a. Based on the inhibition of catechin on yi-yi system, the catechin was measured and the oil was detected. Based on the inhibitory effect of p-ethyl-aminophenol on a luminescent system, an analytical method for the determination of p-ethyl-aminophenol in the drug was established, with a linear range of one. Years old. Recently, based on the inhibition of protein on luminol - tetrasulfonic manganese phthalide blue hydrogen peroxide luminescence system, a new high sensitive chemiluminescence method for the determination of protein was established in combination with flow injection. Many clinically important substances, such as glucose, urea, uric acid, lactic acid, choleol, choline, catecholamines and some enzymes and their substrates, can be produced by certain reactions. Indirect determination of these substances can be realized by the luminescence detection of the generated substances. Applications of luminol in pharmaceutical and environmental analysis The application of luminol in drug and environmental analysis and the study of its reaction mechanism include two parts: review of chemiluminescence analysis and research report. In 1877,Radziszewski discovered that loronine glows green when oxidized in alkaline media by reagents such as hydrogen peroxide. Since then, many similar luminescent compounds have been synthesized, and their luminescence mechanism and application have been further studied. DE sheng technology since the 05 years began to research and development production of luminol, luminol, separation of glue, heparin, EDTA potassium collects blood vessels such as additive, and in vitro diagnostic reagent, the color of the original substrate TOOS, MAOS new Trinder 's reagent, Bicine and Tris biological buffer and luminol, acridine esters such as chemiluminescence reagent has a deep research, the independent research and development and synthesis of professional advantage, DE sheng technology to become the industry's leading brand of the world, to make great contributions to human health. At present, the company has reached a long-term cooperative relationship with many large enterprises