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Wuhan Desheng Biochemical Technology Co., Ltd
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Latest company new about What are the advantages of acridine ester DMAE-NHS?
2021/02/20

What are the advantages of acridine ester DMAE-NHS?

Acridine ester DMAE-NHS can be used for luminescence data collection with a multifunctional microplate reader equipped with an autosampler. Proteins, peptides, antibodies, and nucleic acids can all be labeled with this product. The acridinium ester emits light rapidly under the excitation of basic hydrogen peroxide, so the labeled compound can be detected by collecting photons. This product is mainly used for: chemiluminescence and immunoassay, receptor analysis, nucleic acid and peptide detection, etc. The following mainly introduces the advantages of acridinium ester DMAE-NHS and the calculation method of labeled protein.   Advantages of acridinium ester DMAE-NHS   Compared with traditional acridine esters, DMAE-NHS has higher luminous efficiency, better thermal stability, and stronger hydrophilicity. The chemiluminescence reagent has high photon yield and low background. It is compatible with proteins, antigens, and antibodies. After coupling, the luminous efficiency is almost unaffected, making it an excellent chemiluminescence immunoassay labeling reagent.   Product packaging   Acridinium ester DMAE-NHS also has certain advantages in synthesis. Compared with other acridinium ester chemiluminescent substrates, its synthesis steps are simple, no protecting group strategy is required, reaction conditions are mild, and the product yield and purity are high, and it is not expensive. The chemical reagents and solvents, and the solvents can be recycled, can meet the needs of mass production, and have broad application prospects by reducing the application cost of production and analysis and testing.   Calculating method for the efficiency of acridine ester DMAE-NHS labeling protein   1. Take 100uL of the sample to be tested, and dilute it until Abs280 is between 0.1 and 1.5; 2. Add a small amount of hydrochloric acid to 1 and adjust to pH=1~2 to form a salt solution with yellow characteristics, with an absorption peak at 367nm 3. Test the Abs280nm and Abs367nm of the sample to be tested respectively; 4. Equation1: Acridine ester concentration (mol/L)=Abs367/14650; 5. Correction of protein Abs280 value Equation2: Abs280 (after correction) = Abs280- (Abs367×0.17); 6. Prepare 1mg/ml unlabeled protein solution (e.g. 50ug protein with 50μL labeling buffer), take out 10μL and add 490μL ddH2O (diluted 50 times). Read Abs280nm and multiply by the dilution factor. 7. Calculate the protein concentration (mg/ml)   The acridinium ester DMAE-NHS produced by Desheng not only has simple labeling, but also has high luminous efficiency. Its stability is unmatched by other luminescent reagents. As a professional manufacturer of acridine esters, Desheng has invested in the research and development of acridinium esters. A lot of energy, its products are of high quality and competitive prices. If you are interested in understanding, you can call for consultation. Desheng welcomes you to consult and order.
Latest company new about The detailed preparation steps of 2 - (4 - (2-hydroxyethyl) piperazin-1-yl) ethanesulfonic acid buffer are shown here
2021/02/19

The detailed preparation steps of 2 - (4 - (2-hydroxyethyl) piperazin-1-yl) ethanesulfonic acid buffer are shown here

The chemical name of HEPES buffer is 4-hydroxyethyl piperazine ethanesulfonic acid, cas7365-45-9. HEPES is commonly used in biological buffers, cosmetics, coatings, surfactants, etc. The pH buffer range is 6.8-8.2, which can be used in biochemical diagnostic kit, DNA / RNA extraction kit and PCR diagnostic kit. It has no toxic effect on cells. It is a hydrogen ion buffer, which can control the constant pH range for a long time.   HEPES buffer is often used in cell culture experiments. In the open culture condition, the addition of HEPES buffer can prevent the increase of pH oxidation in the medium, thus maintaining the pH at about 7.0. So, what are the preparation steps and methods of HEPES buffer? Let's introduce them in detail by Desheng.   HEPES powder   Different literatures have different opinions on the preparation of HEPES buffer solution. According to the use, one is pure HEPES + NaOH, the other is HEPES + salt. Various preparation methods are summarized as follows:   1、 Preparation of 500 ml 1 m HEPES, pH = 7.0, stock solution Dissolve 119.15 g HEPES in 400ml distilled water, add 0.5 ~ 1m NaOH aqueous solution to adjust at least the required pH (the effective pH range of HEPES is 6.8 ~ 8.2), then fix the volume to 500ml with distilled water and store at 4 ℃.   2、 HEPES buffer formula with small amount of salt (500ml) HEPES 6.5g, NaCl 8.0g, na2hpo4.7h2o 0.198g, adjust the pH value with 0.5m NaOH solution, and finally fix the volume.   3、 Preparation of 2 × HEPES buffer salt solution Dissolve 1.6g NaCl, 0.074g KCl, 0.027g na2hpo4.2h2o, 0.2g dextran and 1g HEPES in 90ml distilled water, adjust to the required pH value with 0.5m NaOH, and then fix the volume to 100ml with distilled water.   Desheng is a new technology enterprise integrating R & D, production and sales. Its business scope includes "blood collection additive", "in vitro diagnostic reagent", "biological buffer", "pharmaceutical intermediate" and "chemiluminescence substrate". Tris, HEPES, caps, mops are the company's main products.   Desheng's main product biological buffer is a kind of alcohol ammonia fine chemicals with special characteristics. It does not participate in or interfere with the biochemical process. It can be used in the buffer system of life science research and provide a stable pH environment for experiments. Desheng's biological buffer is widely used in in vitro diagnosis, biopharmaceutical, biological beauty, paint and other industries because of its high buffering efficiency and high quality There are dozens of stable customers. Desheng provides one-stop purchasing service. If necessary, you can click the official website to consult customer service.
Latest company new about What are the advantages of carbomer as a pharmaceutical excipient?
2021/02/18

What are the advantages of carbomer as a pharmaceutical excipient?

Since its first application in the 1950s, Carbomer has been highly respected in pharmaceutical circles. Carbomer has been widely used in the research and production of cosmetics and drugs abroad, and has been included in the Pharmacopoeia of many countries, but it is still a relatively new material in China.   Carbomer has many uses in drug punishment. For example, it can be used as a disinfectant gel, Carbomer Eye Drops, Carbomer drug delivery adhesive, Carbomer skin disinfectant gel, and controlled release material. What are the advantages of carbomer as pharmaceutical excipients? Let's give you a solution.   Carbomer powder   Carbomer can be used as ophthalmic gel. At present, the common eye drops used in clinic are short of drug retention in the eyes, resulting in poor drug absorption. But carbomer is different, it not only does not have the above shortcomings, but also in clinical practice it can relieve endocrine disorders, dry eye symptoms caused by insufficient tears, can reduce inflammation and treat presbyopia.   The new bromide eye drops used in the treatment of dry eye disease in clinic is effective because of its short contact time with cornea. Instead, the gel made with carbomer has a significant effect on promoting weeping, and it will produce the greatest effect after 1 hours.   In addition to the ingredients of ophthalmic gel, in the oral protein polypeptides drug delivery system, using carbomer bags around the milk drops can increase the adhesion time between the milk drops and the intestinal wall mucosa. The microemulsion containing carbomer 940 can increase the intestinal absorption of drugs such as desmopressin, while carbomer's protease inhibition and absorption promoting action are also beneficial to increase the drug. Absorptivity.   ​ Carbomer gel   Carbomer 940 is not only easy to smear, but also can absorb tissue solution, which is conducive to the discharge of secretions. It has good stability, smooth and comfortable skin feeling, easy to clean, and good air permeability. Some oral drugs are made into gel through skin, and become topical drugs, which reduces the stimulation of internal organs. When used for skin external use, Carbomer also has moisturizing property, can lubricate skin, protect skin from pollution and stimulation, and has anti infection effect.   It should be noted that carbomer is used as a pharmaceutical excipient and does not have any other drug effects. It is used as gel, thickener, dispersant or suspending agent as a carrier medium for medicine. Desheng is a professional manufacturer of carbomer. Its products mainly include carbomer 980 and carbomer 940. The customer response is very good. Carbomer is a new type of polymer material. Excellent pharmaceutical excipients will play a certain role in promoting the use of new excipients and the research of new preparations in China.
Latest company new about What are the functions of 3-cyclohexylaminopropanesulfonic acid (CAPS)?
2021/02/17

What are the functions of 3-cyclohexylaminopropanesulfonic acid (CAPS)?

Caps, CAS: 1135-40-6. What we're familiar with is that it's one of the good's buffers. It is widely used in biochemical diagnostic kits, DNA / RNA extraction kits and PCR diagnostic kits. In addition to the applications we know, what other fields are we not familiar with?   In nucleic acid extraction, 3-cyclohexylaminopropane sulfonic acid (CAPS) and 3 - [(3-cholamidopropyl) dimethylammonium] - 1-propanesulfonate (chaps), 3 - (cyclohexylamino) - 2-hydroxy-1-propanesulfonate (capso), and 2 - (cyclohexylamino) ethanesulfonate (ches) were used to prepare the solution for nucleic acid hybridization, which could reduce the yield of non-specific hybridization products, improve the specificity of nucleic acid hybridization, and maintain the stability of nucleic acid hybridization The yield of the target hybrid product was determined. It has important value in the identification of specific pathogens, the diagnosis of genetic diseases and the analysis of gene sequences.     Caps can also be used in a variety of environment-friendly high-quality waterborne two-component polyurethane coatings. Many coatings do not perform well in terms of drying, curing and chemical resistance, while caps performs well. It can be used as water-based isohydroester curing agent and can coexist with resins containing active groups (hydroxyl group, carboxyl group, amino group, epoxy group, etc.) for a long time at room temperature. This is one of the reasons why caps is more and more favored by the water-based coatings market.   In addition to the above uses, caps is also used to improve waterborne coatings, flux for welding materials, heat exchange carrier for air conditioning equipment, raw materials for lithium metal manufacturing process, pyrotechnics, dry batteries, etc.   In addition, caps is more suitable for transferring small molecular weight proteins to PVDF membrane or nitrocellulose membrane as Western blotting transfer buffer or transmembrane buffer; in addition, caps is also used as eluent in cation exchange chromatography, running buffer in capillary electrophoresis, enzyme determination buffer, etc.   Caps buffer with such excellent performance has become a hot demand in the market, both in the field of Biochemistry and home decoration. The caps produced by Desheng company is reagent grade, with a purity of more than 99%. It can not only be used as buffer of in vitro diagnostic reagent, but also be well applied in coatings. Our products have good performance and many cooperative manufacturers. Thank you very much Everyone's trust in us, we will continue to unremittingly provide our customers with high quality products.
Latest company new about Desheng carbomer supplier, carbomer problem collection
2021/02/16

Desheng carbomer supplier, carbomer problem collection

Carbomer is a kind of acrylic crosslinking resin which is crosslinked with acrylic acid by pentaerythritol and so on. It is a very important rheological regulator. After neutralization, Carbomer is an excellent gel matrix with thickening, suspension and other important uses. Its technology is simple and its stability is good. It is widely used in emulsion, cream and gel. Although there will be a simple text description on the introduction of each raw material, how much do you know about the full knowledge of carbomer? As a manufacturer of Carbomer, Desheng summarizes the product knowledge of carbomer.   essential information   Name: Carbomer, polyacrylic acid; carboxyl ethylene copolymer Appearance: white powder Solubility: soluble in water, 0.2% 940 soluble in water, white translucent liquid, add triethanolamine or sodium hydroxide to dissolve The liquid was colorless, transparent and sticky gel. Thermal stability: swelling in water, generally at 80 ℃ - 85 ℃ Photostability: carbomer neutralized with triethanolamine or sodium hydroxide solution is easy to dilute under long-term natural light   carbomer powder   Determination method   Method name: Determination of carbomer potentiometric titration Scope of application: this method uses potentiometric titration to determine the content of carbomer. Method principle: the test sample was dissolved in water, titrated with sodium hydroxide titrant according to potentiometric titration method, and the carbomer content was calculated.   Reagents: 1. Water; 2. Sodium hydroxide titrant (0.25 mol / L); 3. Standard potassium hydrogen phthalate Operation steps: take about 0.4g of this product, accurately weigh it, evenly disperse it in 400ml water, stir to dissolve it, titrate with sodium hydroxide titrant (0.25mol/l) according to potentiometric titration method (when it is near the end point, stir at least 2 minutes after each drop). Every 1 ml sodium hydroxide titrant (0.25 mol / L) is equivalent to 11.25 Mg - COOH.   Thickening method   1. Neutralization thickening Sodium hydroxide and triethanolamine are commonly used as neutralizers, which is the reason why carbomer is sensitive to ions.   2. Hydrogen bond thickening Carbomer molecule as carboxyl donor can combine with one or more hydroxyl groups to form hydrogen bond and thicken. This neutralization method takes time. The commonly used hydroxyl donors are nonionic surfactants, polyols and so on.   carbomer gel   Configuration taboo   1. Carbomer discolors with m-diphenol and is incompatible with phenol, cationic polymer, strong acid and high concentration electrolyte. Some antimicrobial agents should also be avoided or used in low concentration. Trace amounts of iron or other transition metals can catalyze the degradation of carbomer dispersions. When carbomer comes into contact with strong alkali substances such as ammonia, sodium hydroxide, potassium hydroxide or strong basic organic amines, a large amount of heat can be generated.   2. Some drugs with amino functional groups can form water-soluble complexes with carbomer. Usually, this situation can be prevented by adjusting the solubility parameters of liquid with appropriate alcohol or polyol.   3. Carbomer can also form pH dependent complexes with some polymer excipients, and adjust the solubility parameters, which can also play a role in this condition.   susceptibility   1. Mechanical shear after carbomer neutralization, long-term stirring or high shear stirring will cause viscosity loss   2. The presence of ions - electrolytes reduce thickening efficiency   3. UV - long term ultraviolet irradiation will make the carbomer gel less sensitive to ultraviolet radiation when its viscosity is reduced by pH>/=10.   4. temperature change carbomer gel is not affected by temperature.   5. microorganism carbomer does not support the growth of bacterial mold, and the growth of bacterial mold does not affect the gel properties. The conventional dosage is 0.2-0.4%, which can replace 3-7% of conventional emulsifier. Carbomer polymer has almost no properties of surfactant, so adding 0.1-0.5% low HLB surfactant can adjust the oil phase particles to be smaller, so as to prepare white and delicate cream products.   purpose   1. Emulsifier   (1) It is effective at very low concentration of 0.1-0.5%, replacing the traditional surfactant dosage of 3-7%; (2) It is not limited by HLB and PLT; (3) It can emulsify any liquid oil at room temperature; (4) If the wax is melted in the manufacturing process, it can be emulsified; (5) The stable emulsions can be prepared by making full use of the wetting, dispersing and adhering functions of surfactants; (6) When rewetting, it will not emulsify again, so it is easy to prepare waterproof emulsion without film-forming agent; (7) High oil phase can be dissolved into water to form (O / W) emulsion; (8) can be prepared: moisturizing cream, lotion, cleansing products, sunscreen products, alcohol free perfume, flavor conditioner (enhanced gloss, easy to comb), hand washing agents, low consistency spray emulsion and transparent microemulsion.   2. Used in skin care products   Hydrophilic thickener, stable emulsifier, suspending agent and gel have good transparency. It is necessary to maintain moderate to weak alkalinity to have consistency. Therefore, it is impossible to coexist with acid active ingredients. In addition, Carbomer is also afraid of salts. Therefore, mineral ions can not be added, otherwise the consistency will disappear and irritation to the eye mucosa.
Latest company new about Thickening mechanism and dissolution method of carbomer
2021/02/15

Thickening mechanism and dissolution method of carbomer

Carbomer is a kind of nano grade acrylic acid resin. When water is rising and a small amount of mixture is added (such as triethanolamine and sodium hydroxide), a high transparent gel is formed. Different types of carbomer represent different viscosity, such as short rheological or long rheological, such as: carbomer 940 has short rheological property, and its viscosity reaches 63000MPA.S at 0.5%. It is suitable for high viscosity products. Carbopol 941 has long rheological properties, and its viscosity reaches 7500mpa. S at 0.5%. It is suitable for low viscosity products. Carbopol 941 has ion or salt resistance, and is suitable for daily chemical and industrial products.   The thickening mechanism of carbomer is as follows   Neutralization thickening: carbomer is usually neutralized to form salt, which makes the curly molecules thicken due to the opening of electric repulsion force. Sodium hydroxide and triethanolamine are commonly used neutralizing agents, which is also the reason why carbomer is sensitive to ions. Hydrogen bond thickening: as carboxyl donor, Carbomer molecules can combine with one or more hydroxyl groups to form hydrogen bond and thickening. This neutralization method takes time, and the commonly used hydroxyl donors are non-ionic surfactants, polyols, etc.   There are two dissolution methods of carbomer A: The common method is to dissolve every other day. If you want to use it on the next day, soak it on the previous day. First, add carbomer into deionized water according to the actual production requirements to dissolve it without stirring. After carbomer absorbs water naturally, the neutralizer (triethanolamine or sodium hydroxide solution) is added, adjust the pH value to about 7, and use a round tool or disperser And stir evenly at low speed.   B: was dissolved by high-speed dispersant and added to the actual production ratio. The disperser did not have white powder and added neutralizer to form the gel. Then the vacuum emulsification pot was used to remove the air from the gel, and then worry too much.     It should be noted that when using common methods, Carbomer can not be stirred in water. For example, when adding carbomer while stirring, Carbomer will form a white water ball. The surface has absorbed water, but there is no water in it. After neutralization, many water white spots can be seen, and a large number of bubbles can be formed. Carbomer has high viscosity, and bubbles are difficult to eliminate by themselves. Even if a certain amount of defoamer is added, it is difficult to eliminate the bubbles. In this case, the vacuum pot can only be used to eliminate the bubbles, which increases the difficulty of operation to a certain extent.   Warm tips of carbomer dissolution The dispersion time of various types of carbomer in water is related to the water temperature and quality. It is recommended to use deionized water to make the product more stable. If it is dissolved directly in organic solute, it will take longer. For example, for solid alcohol, Carbomer 940, 941, 934, 980 and 981 need soaking for about 8 hours, Carbomer 2020 U10 U20 needs to be soaked for about 4 hours. The specific dissolution time is related to the dissolution amount. If you have more questions, please contact the customer service on Desheng's official website at: www.whdsbio.com
Latest company new about Nucleic acid detection assisted by covid-19 Virus Transport Media
2021/02/14

Nucleic acid detection assisted by covid-19 Virus Transport Media

Novel coronavirus pneumonia has been nip in the bud. Recently, the European and South American multi national epidemic situation is again in urgent demand. The three regions of France and Spain, the two Greek area are again blocked, and the emergency situation in many countries is once again extended. Although our country is relatively safe at present, it is also necessary to intensify the prevention and control of the epidemic side to prevent the disease. In response, it is not too much to say that it is a worthy meritorious official to launch an efficient and stable Virus Transport Media to assist nucleic acid detection.   First of all, let's understand the characteristics of the virus. The virus is composed of a nucleic acid molecule and protein or only protein. The individual is small and the structure is simple. The common epidemic infectious diseases are usually RNA viruses, such as influenza virus, HIV and influenza A virus.   Because there is no cell structure, the virus itself can not replicate. Instead, it invades the host cells with genes and uses the latter's replication system to replicate new viruses. What we call COVID-19 is also RNA virus. New Coronavirus is not an independent life body. It needs invasion to live cells. It can reproduce and release more progeny virus particles by using the energy and material and molecular encoding function of living cells.     High concentration guanidine salt can quickly inactivate and preserve respiratory pathogens in inactivated Virus Transport Media, which makes the samples lose infectivity. The inactivated samples can be used with a variety of virus DNA / RNA extraction kits, M32 / M96 nucleic acid extraction instrument for rapid nucleic acid extraction, and PCR detection kit for respiratory pathogens for rapid detection. The specificity and sensitivity are not affected.   In addition to inactivated virus, there are also non inactivated virus. The non inactivated virus contains Hanks solution, gentamicin, fungal antibiotics, BSA (V), cryoprotectants, biological buffers and amino acids. The combination of multiple antibiotics has anti-tumor effect   The function of bacteria and antifungal; bovine serum albumin (BSA) as a protein stabilizer can form a protective film on the protein coat of the virus, making it not easy to decompose and ensuring the integrity of the virus; the neutral environment constructed by Hanks buffer can help to increase the survival time and infection stability of the virus.   Desheng's non inactivated Virus Transport Media has the advantages of good sampling effect and more accurate detection. It can provide free samples of {Virus Transport Media} according to customers' needs. Desheng's Virus Transport Media has both inactivated and non inactivated types, which can meet the different needs of different organizations for Virus Transport Media. Each bottle is packed with 1L and 5L separately, which is convenient to use, with good sampling effect and reliable quality, For you to bring a different use experience. For example, the conventional packaging is 1L / bottle and 5L / barrel. Of course, if you need other specifications, it also supports customization.
Latest company new about What is 4 - (2-hydroxyethyl) - 1-piperazineethanesulfonic acid
2021/02/13

What is 4 - (2-hydroxyethyl) - 1-piperazineethanesulfonic acid

HEPES buffer is 2 - (4 - (2-hydroxyethyl) piperazine) ethanesulfonic acid, CAS 7365-45-9. This buffer is usually used in biochemical experiments to adjust the pH value of the reaction system, such as virus preservation solution or cell preservation solution.   There are two types of HEPES buffer on the market: powder reagent and solution reagent. The concentration of HEPES solution is 10-50 mmol / L, and the buffer capacity can be achieved when the culture medium contains 20 mmol / L HEPES. Moreover, this kind of buffer has many advantages over phosphate buffer. It is non-toxic to cells and can control the constant pH range for a long time. It is a good hydrogen ion buffer.   hepes powder   The dissociation constant of HEPES buffer is 7.65 (at 20 ℃), and the pH buffer range is 6.6-8.6, which is generally suitable for the reaction system with pH 6.8-8.2. It can be used directly with sodium hydroxide, or mixed with salt and adjusted pH with sodium hydroxide.   1、 500 ml of 1 mol / L HEPES, pH 7.0, stock solution: weigh 0.5 mol (119.15 g) of hydroxyethyl piperazine ethanesulfonic acid, then adjust to the required pH value with 0.5 m ~ 1 M sodium hydroxide, finally fix the volume with distilled water, and seal at 4 ℃.   2、 HEPES buffer 500ml with a small amount of salt: HEPES > 6.5g, NaCl > 8.0g, na2hpo4.7h2o > 0.198g, adjust pH value with 0.5m NaOH > water solution, finally fix volume and store at low temperature.   3、 Preparation of 2 × HEPES buffer salt solution: 1.6g NaCl, 0.074g KCl, 0.027g na2hpo4.2h2o, 0.2g glucan or dextran and 1g HEPES were dissolved in 90ml distilled water, adjusted to the required pH value with 0.5m NaOH, and then diluted to 100ml with distilled water.   Although the buffer system of HEPES is not as extensive as that of PBS, it has more advantages. The ionic strength of PBS is higher than that of HEPES, and the ionic strength will affect the solubility of other solutes in the mixed solution. In general, where PBS can be used, HEPES can be used, but where HEPES is used, PBS cannot be replaced.   HEPES buffer is similar to pipe, but the water solubility of pipe is poor, so it can be made into sodium salt of pipe. The two buffers provided by Desheng are powder reagents, which can also be prepared into ready-to-use buffer solutions with specific concentrations if required.
Latest company new about Biological buffer n, N-bis (2-hydroxyethyl) glycine
2021/02/13

Biological buffer n, N-bis (2-hydroxyethyl) glycine

Bicine, N, n-di (hydroxyethyl) glycine, CAS 150-25-4, is a white crystalline powder. Soluble in water, insoluble in acet one, DMAC, DMSO, DMF and other organic solvents.   Bicine buffer is a pH buffer suitable for biochemical and medical research. In the range of pH 7.6 ~ 9.0, the pKa value is 8.3 at 25 ℃. This property makes bicine often used as a buffer solution for capillary electrophoresis. It is also the recommended buffer for low temperature biochemical work. Its molecular structure is similar to glycine. Buffer is recommended in low temperature biochemical work of biological buffer. It was used to prepare stable substrate solution for the determination of serum guaninase. It is also a widely used buffer for enzyme reaction buffer and electrophoresis buffer. The working concentration is 3-100ml   Product packaging   [recommended usage]   1. Preparation of storage solution for cell culture related experiments: dissolve according to the solubility in the table. If it is used for cell experiment, please prepare the liquid and filter it with 0.22um before adding cells.   2. Preservation of storage liquid: it is recommended to prepare and use the liquid now, and the liquid is not very stable; it can also be packed into a single dosage, which is stable for 2 years. Avoid repeated freezing and thawing.   Since 2005, Desheng technology has been specialized in R & D and production of separation gel, heparin, EDTA potassium salt and other blood collection additives, as well as in vitro diagnostic reagents. It has made deep research on new Trinder's reagents such as chromogenic substrates Mao and toos, biological buffers such as Tris and bicine, and chemiluminescence reagents such as luminol and acridine ester. Our company has a professional independent R & D team and has great potential in synthesis Professional advantages, product quality and technology, at home and abroad has been widely recognized and used by customers. The purity of bicine produced by Desheng technology is more than 99%, with good water solubility and stable process, which can ensure the appearance of pure white crystal powder.
Latest company new about High quality supplier of 3 - (cyclohexylamine) - 1-propanesulfonic acid (CAPS)
2021/02/12

High quality supplier of 3 - (cyclohexylamine) - 1-propanesulfonic acid (CAPS)

Biological buffers caps are widely used in biochemical diagnostic kits, DNA / RNA extraction kits and PCR diagnostic kits, as well as in enzyme chemistry and HPLC separation of alkaline drugs. Caps buffer also has many applications in industry, such as new coatings and new materials. Caps is also a raw material for manufacturing welding materials, air conditioning equipment and lithium metal. In the face of caps with such a wide range of applications, there are certainly many manufacturers. We should pay attention to the following problems when selecting manufacturers.   Hubei xindesheng Material Technology Co., Ltd. is located in Gedian Development Zone, Ezhou City, Hubei Province. It has 14 years of R & D and production experience in the field of biochemical industry. It mainly produces in vitro diagnostic reagents such as biological buffer, blood sampling additive and chemiluminescence substrate. The company has passed the ISO-9001 quality management system certification , has a good reputation in the industry, is a reliable biochemical raw material production enterprises.     2. Caps needs better purity when it is used as biological buffer. Generally, it needs analytical purity. When it is used in industry, the purity requirement is relatively low, but it also needs different treatment for different applications. All the biological buffers produced and developed by Desheng are of analytical purity, caps, Tris, bicine, mops and other purity ≥ 99%, and the process is stable, which is your reliable choice.   3. If you are purchasing new coating materials, you need to understand the advantages of caps from different manufacturers in the application of coatings. Compared with other manufacturers, Desheng caps has obvious advantages in the application of new coatings. It completely surpasses other manufacturers in the aspects of dryness, curing and chemical resistance. It can be used in various environmentally friendly high-quality waterborne, two-component polyurethane coating formulations, and can be used with The new regulations require further reduction of VOC (volatile organic compounds) content in decoration materials, which greatly increases the amount of these crosslinking agents. Compared with general solvent based coatings, caps produced by Desheng will not have the problem of film quality degradation.   Desheng chemical has rich experience in the production and research of caps and other biological buffers. Caps is not only widely praised in the field of biochemical diagnosis, but also widely used in the new coating market. Desheng is rising step by step with the rapid development of the medical industry!
Latest company new about Carbomer 940 supplier recommendation
2021/02/11

Carbomer 940 supplier recommendation

Carbomer 940 is widely used in all kinds of daily chemical products due to its excellent thickening, suspension and stability. It is also found in our daily products such as bath gel, cream and skin care products. Carbomer 940, because of its important application in hand free disinfectant gel, has caught fire during the epidemic. As more and more businesses invest in the research and development of carbomer 940, purchasers take a look. Is there a better carbomer 940 supplier recommendation?   The answer is yes. After repeatedly comparing the products of different manufacturers, it is found that the carbomer 940 produced by Desheng is very worthy of recommendation. The reasons are as follows.   carbomer gel   1. Desheng has a group of powerful R & D and production teams   Desheng technology, founded in 2015, is located in Ezhou City, the famous "city of hundreds of lakes" and "land of fish and rice". The company has a group of high-quality production personnel, strong development ability technical team and ability to deal with and solve various complex technical problems. It has always been famous for its good business reputation.   2. Desheng is the direct manufacturer of carbomer 940   Although there are many manufacturers of carbomer 940 in China, some of them are not good in quality. They just think that it is the trend of the times, and they have not invested in human, material and financial resources. Desheng has its own professional R & D team and production base, so it doesn't have to worry about product quality problems at all. Even if there are problems in use, it can return goods without worry. Only the manufacturer can give such a service commitment .   3. Preferential price of carbomer 940 provided by Desheng   You must have repeatedly compared the price when you are looking for the supplier of carbomer 940. Finally, you will find that Desheng is the manufacturer who really takes action. Desheng clearly tells you that the manufacturer has direct sales, sufficient stock, and can enjoy the price of 100 yuan / kg for tons or above. Many customers can't believe it when they see these words. Desheng hereby declares that this activity is real and effective, and the activity is not complete The deadline is November 26, 2020. If you miss this wave of discounts, there will be no next time.   4. Desheng cabom 940 has high daily output and can deliver goods quickly   Desheng has a specialized production base with imported production equipment, with a daily output of 3-5 tons, To meet the needs of large quantities of customers, no matter what the customers want is kilogram or ton goods, Desheng has the ability to deliver goods quickly. As many as 100 + customers cooperate with Desheng. They are sold at home and abroad and have rich export experience. Customers no longer have to worry about the delivery cycle.
Latest company new about Desheng vascular additive tells you that different color caps have different effects
2021/02/10

Desheng vascular additive tells you that different color caps have different effects

There are many kinds of additives for blood collection, such as anticoagulants, accelerators, separation gels, etc. In order to distinguish the use of different blood collecting vessels and additives, different cap colors are used internationally to mark blood collecting vessels. The functions of different color caps are different, some added anticoagulants, some added accelerators, and some blood collecting vessels without any additives. What is the role of different additives in blood collection? Desheng, as an old manufacturer of vascular additive, can help you solve your doubts.   Red head: no additives, common serum tube for routine biochemical and immunological tests.   Orange red head cap: coagulant, can activate fibrin, make soluble fibrin into insoluble fibrin polymer, and then form a stable fibrin clot. The rapid serum tube can coagulate the collected blood in 5 minutes, which is suitable for emergency series tests.   Golden head cover: separation gel and accelerator. After centrifugation, the separation gel can completely separate the liquid components (serum or plasma) and solid components (red blood cells, white blood cells, platelets, fibrin, etc.) in the blood, and completely accumulate in the center of the test tube to form a barrier. The sample remains stable within 48 hours. Coagulant can quickly activate the coagulation mechanism and accelerate the coagulation process, which is suitable for emergency series tests.   Green head cover: heparin, suitable for hemorheology, erythrocyte fragility test, blood gas analysis, hematocrit test, general biochemical determination. Heparin has the function of antithrombin and can prolong the clotting time of samples, so it is not suitable for hemagglutination test. Excessive heparin can cause leukocyte aggregation and cannot be used for leukocyte count. Because it can make the background of blood stained light blue, it is not suitable for morphological examination. Light green head cover: separation gel and heparin lithium can achieve the purpose of rapid separation of plasma. It is the best choice for electrolyte detection. It can also be used for routine plasma biochemical detection and emergency plasma biochemical detection in ICU.   Purple head cover: EDTA anticoagulant, the anticoagulant is ethylenediamine tetraacetic acid (EDTA), which can combine with calcium ion in blood to form chelate, and make Ca2 + lose coagulation, so as to prevent blood coagulation. It is suitable for many kinds of hematological examination. However, EDTA can affect platelet aggregation and is not suitable for coagulation test, platelet function test, calcium ion, potassium ion, sodium ion, iron ion, alkaline phosphatase, creatine kinase and PCR test.   Light blue head: sodium citrate anticoagulant, sodium citrate mainly through chelating with calcium ions in blood samples and anticoagulant effect, suitable for coagulation test.   Black head cover: sodium citrate ESR test tube, the concentration of sodium citrate required for ESR test is 3.2% (equivalent to 0.109 mol / L), and the ratio of anticoagulant to blood is 1 ∶ 4.   Gray head cover: potassium oxalate / sodium fluoride. Sodium fluoride is a weak anticoagulant. It is usually used in combination with potassium oxalate or sodium ethyliodate. The ratio is 1 part of sodium fluoride and 3 parts of potassium oxalate. It can not be used in the determination of urea by Urease method, nor in the determination of alkaline phosphatase and amylase. It is recommended to be used in the determination of blood glucose.   What we should pay attention to after blood collection: A. After the injection of blood, pay attention to shake well, the force should be moderate to prevent hemolysis. B. The amount of blood injected should be strictly in accordance with the volume marked on the test tube. C. The blood from different color tubes should not be poured into other color tubes, otherwise it will lead to wrong results. D. The needle should not contact the wall of the test tube to avoid contact with anticoagulant, resulting in wrong results.
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