China Wuhan Desheng Biochemical Technology Co., Ltd Company News

As we all know, for patients with diabetes, in addition to fasting blood glucose and postprandial blood glucose, glycosylated hemoglobin, as a gold indicator of blood glucose control, can reflect the average level of blood glucose control in 2-3 months, and should be reviewed every two to three months. In addition, there are two tests are also very important, that is, patients with diabetes often need to go to the hospital for insulin and C peptide testing.   Insulin is a very important hormone for human body, it has a good effect in lowering blood sugar. Studies have shown that there are many methods to measure insulin, and the requirements of each method are different. So this article will take friends to understand the detection methods of insulin?   Insulin is a peptide hormone secreted from islet B cells. Insulin secretion is insufficient, which can cause diabetes. But with the continuous improvement of people's living standard, the development of medical level and the change of people's concept of health, the incidence rate of diabetes is increasing rapidly. It has become a chronic and serious disease that plagues many elderly people. At present, chemiluminescence immunoassay (CLIA), enzyme-linked immunosorbent assay (ELISA) and radioimmunoassay (R1a) are the most commonly used methods in clinic.   The following is a brief introduction to the basic detection principle of insulin. The function evaluation of islet B cells is usually achieved by measuring insulin in serum. In the radioimmunoassay experiment, excessive labeled antigen * Ag and unlabeled antigen Ag (i.e. the antigen to be tested) are added to competitively bind with a small amount of antibody (AB). If the radioactivity of the conjugate (* Ag AB) measured by the experimental results is higher, it means that the concentration of the substance to be measured is lower. If the radioactivity of the measured conjugate is low, it means that the concentration of the analyte is high. By analyzing the standard curve, the concentration of the analyte can be calculated.   In 1960, the rapid development of endocrine science fully proved the great impetus of radioimmunoassay. In 1977, the inventor of this technology won the Nobel Prize for biomedicine. Subsequently, this new technology quickly penetrated into other fields of medical science, such as virology, pharmacology, hematology, immunology, forensic medicine, oncology, etc. radioimmunoassay plays a great role in promoting the progress of biomedicine in China. Desheng biochemical has a lot of raw materials supporting immunoassay, such as chromogen substrate, chemiluminescence reagent, biological buffer, etc.   The above is the method of insulin detection, hope to help friends. In fact, friends in the detection of insulin or should be in the morning 7 ~ 11 o'clock, and take the morning of the first small make-up to the hospital. In the diet or should pay attention not to eat with more sugar food. Otherwise, we will see the results of insulin test. If so, what do not understand the place can also look for expert consultation

After experiencing a wave after wave of shocks, carbomer has completely stabilized the domestic market. Many manufacturers have invested in Boca. However, it is difficult to buy high-quality and low-cost carbomer products when purchasing. The quality of the products is not satisfactory. Now I'd like to share with you how to buy high-quality and low-cost carbomer.   1. Carbomer products are all from manufacturers   When you buy products, try to find the manufacturer to reduce the price difference between middlemen. Desheng is a manufacturer with a professional R & D team, with 6 technicians and 10 production personnel.     2. Is there any spot supply   It is believed that the buyers of Carbomer, after consulting many companies, find that even though the number of suppliers has increased a lot, the supply of carbomer raw materials has not improved much. There are still many manufacturers who are in the list and do not supply in time. In addition, many manufacturers started production after the epidemic. Both the production equipment and technology are not mature enough, resulting in a small production volume. Therefore, it is still difficult to buy carbomer. Desheng, as the real producer of carbom, has sufficient stock and an average daily output of 3-5t.   3. Product quality   As a manufacturer of Carbomer, Desheng supports customization of some indicators for different industries and uses. Moreover, the carbomer powder produced by us is obviously white, and the powder is more fluffy and delicate. In the configuration of solvent, the transparency is much higher than that of similar products. The conventional carbomer is made into gel, the appearance is more transparent, and the viscosity can be customized according to individual indexes.     4. Is there a perfect after-sales service   When we buy any product, we can't say that there are no problems. If there is no good after-sales service in case of quality problems or other problems, who should we look for in the middle of any loss? So it is very important to find a manufacturer with perfect after-sales service. And Desheng company has perfect after-sales service. Desheng promises that any quality problem can be returned or replaced. Free samples can be applied for trial, so that the trial before purchase.   5. Is there a reasonable price   Finally, with the above conditions, we are most concerned about the price. Generally, the price of good products will be on the high side. However, in order to thank you for your strong support, Desheng has launched a limited time discount before the year. The price is as low as 130 yuan / kg. Don't have any doubt, as long as the customers who cooperate with us will know that our Desheng company has been adhering to the "letter" word and has gone through 15 years of ups and downs.

Carbomer has strong hygroscopicity and weak acidity (weaker than acetic acid). It can be neutralized by alkaline substances, forming high transparent gel, and high viscosity and viscosity increasing effect. Only a very low dosage is needed to produce high effective thickening without being affected by temperature, and can make some insoluble additives (particles, oil drops, etc.) permanently suspended. So it can be made into various kinds of gelatin in daily chemicals and skin care products, as well as pharmaceutical gels, such as Carbomer Eye Drops, Carbomer gynecological gel, etc.   Carbomer 940 and carbomer 980 are the most widely used. According to the characteristics of different products, there are many other models. What are the total models of carbomer? In fact, according to the relatively large series, Carbomer can be divided into two categories: carbomer 900 series and carbomer 1300 series. CP products of different types and uses can be obtained by controlling the relative molecular weight and crosslinking degree of polymers. The characteristics and applications of some or several different carbomer models are introduced below.     1. The characteristics of carbomer 934, Carbomer 934p and carbomer 974P: good thickening effect, strong shear resistance, permanent stability at high viscosity and short flow in aqueous solution, which are very suitable for cream cosmetics. Among them, 934p 974P is more suitable for pharmaceutical preparations because of the small amount of residual solvent or non-toxic solvent.   2, the characteristics of carbomer 940 and carbomer 980: in this two, Carbomer is relatively more used in daily chemical products. Because of its highly effective thickening effect, it produces clear and transparent water or alcohol water gel, and its rheological property is very short. It is very suitable for all kinds of advanced cosmetics and hand sanitizer gel.   3, CP934P, CP971P, CP974P (P represents the Pharmacopoeia level) can release the drugs in zero or near zero mode. They have the characteristics of rapid and effective gelation, and have good controlled release at very low concentrations, so they are often used as accessories for oral preparations.   After reading the above introduction, we know that carbomer has such a variety of models, and there are some differences in application. At present, Desheng mainly produces two kinds of carbomer 980 and 940, which have high transparency, fluffy powder and white color. The viscosity can be adjusted according to the buyer's requirements. The products have detailed test reports on various parameters, and customers can purchase according to their requirements Sheng has been increasing investment in R & D and production. Now the daily output can reach 3-5 tons, and the supply is sufficient. At present, the activity price of ton level is 130 yuan / kg. Customers can take advantage of the preferential activities to stock up in advance.

Anticoagulants are chemical agents or substances that can prevent blood coagulation. Commonly used anticoagulants are heparin, EDTA, citrate, oxalate and so on. Although we need to choose the appropriate anticoagulant according to different requirements in practical application, their basic performance is still the same as that of blood coagulation. Therefore, we need to know several points in the process of use:   1、 After taking blood with anticoagulant blood collection, how to place it and how long can it be placed   We in the Department of Hematology, laboratory commonly used to anticoagulant tube, anticoagulant tube, as the name implies, is to add anticoagulant blood collection, it is mainly used to save blood, prevent blood coagulation. Generally speaking, how long the anticoagulant tube can keep blood is mainly determined by the anticoagulant substances in the anticoagulant tube. Anticoagulant substances mainly include heparin and liquid.   In addition, the test items are different, and the storage time is also different. If the blood routine and other morphological examination, in 2 to 8 degrees can be preserved for 7 days, if the biochemical test, generally not more than 12 hours. If it is blood glucose test, the result will be inaccurate after 2 hours without refrigeration and adding other reagents.     2、 Several factors affecting the anticoagulant effect are as follows   (1) Blood flow is not smooth, resulting in coagulation without mixing with anticoagulants.   (2) The amount of anticoagulant is insufficient or ineffective.   (3) Blood samples and anticoagulants were not completely mixed (especially solid anticoagulants, such as blood routine) or forgot to mix due to staff error.   (4) The use time of pressure pulse band is too long, which can accelerate coagulation reaction. It is difficult to find the micro coagulation assembly, which leads to abnormal results, such as the influence of micro agglutination on blood routine test and coagulation series test.   (5) Use anticoagulants correctly. In general, serum is often used as sample in clinical test, and anticoagulant is not required. However, when anticoagulant is required for some special test items, attention should be paid to the selection of appropriate anticoagulant and the ratio of anticoagulant to blood. To prevent the change of red blood cell morphology.   In particular, anticoagulants containing K and Na salts cannot be used for the determination of K +, Na +, and those containing EDTA and oxalate cannot be used for the determination of Ca + +, because Ca + + can form insoluble substances with them. Oxalate and fluoride can not be used to determine enzymes and samples determined by enzymatic method, because they can activate or inhibit some enzyme activities. For example, oxalate can inhibit the activities of amylase, acid phosphatase and lactate dehydrogenase. Fluoride can activate urease and amylase.   Desheng is an old brand manufacturer of blood vessel additives. It has formed independent intellectual property rights and professional production and research ability in the aspect of blood collection additives. It has provided products and raw material solutions for more than 100 domestic and foreign manufacturers. The anticoagulant products of blood samples include heparin sodium, heparin lithium, trisodium citrate, EDTA dipotassium, EDTA potassium, potassium oxalate, etc.; the blood sample anticoagulant series products include blood coagulant powder, blood coagulant, etc.; the materials used for blood sample pretreatment include separation gel, silicification agent, etc.

Hubei xindesheng, founded in 2017, is a new technology-based enterprise established on the basis of Wuhan Desheng Biochemical Technology Co., Ltd. (2005). It is specialized in the R & D, production and sales of blood collection additives and blood test reagents. It has perfect equipment and R & D team, including blood collection additive, chemical photo reagent, biological buffer, enzyme preparation, new Trinder's reagent, antigen antibody and other products. In addition, it has formed independent intellectual property rights and professional production and research ability in the aspect of blood collection additives. We have accumulated rich knowledge and experience in blood sample pretreatment and have professional technical service advantages.   At present, the company mainly includes: Blood collection additives: serum separation gel, heparin sodium, heparin lithium, EDTA potassium, EDTA potassium, coagulant, silicification agent, sodium citrate, potassium oxalate, etc;   Chromogen substrate (New Trinder's reagent): toos, tops, ADOS, ADPS, Alps, Daos, hdaos, MADB, Maos, etc; Biological buffers: Tris, Tris HCl, bicine, caps, mops, taps, EPPs, HEPES, PEP, pipes, etc   Luminescent reagents: acridine ester dmae-nhs, acridine ester nsp-dmae-nhs, acridine salt nsp-sa, acridine salt nsp-sa-nhs, acridine hydrazide nsp-sa-adh, acridine ester me-dmae-nhs, luminol, isoluminol, etc   Viral transport medium and carbomer series products specially launched for covid-19;   As a manufacturer, many products can be customized according to the needs of customers. In addition to product quality assurance, we also have advantages in price and after-sales service. No matter at home or abroad, we have maintained a good reputation, including a lot of domestic and foreign famous companies cooperating with us.

Some time ago, Carbomer can be described as crazy, once there was a state of price and no goods. In the final analysis, this is inseparable from its own value. Because it is a kind of polyacrylic acid cross-linked polymer, mainly used in our daily chemical products, a wide range of uses, which led to a shortage of the market.   Now more and more enterprises have joined the industry of producing Carbomer, which leads to the price fluctuation of carbomer. Although the fluctuation range is not very large compared with before, there are many practical problems related to the process. If you want to buy a lot of products at a price you want to spend a lot of time and experience.   Now there is good news to tell you, not only can let you buy good products, but also can have a close price. Desheng company now introduces carbomer 940 and carbomer 980, which are sufficient in stock, and the price is reduced to the ton level price of 19.8 US dollars / kg, which is enough. Manufacturers direct sales, spot direct supply, avoid the price difference between middlemen and buy carbomer in the end. Moreover, the carbomer powder produced by us is obviously white, and the powder is more fluffy and delicate. In the configuration of solvent, the transparency is much higher than that of similar products. As Desheng is a direct manufacturer, individual indicators can also be customized.   On the basis of such preferential treatment, we have a strong after-sales team in addition to the price advantage. Our R & D team will help you solve any doubts about the product. Don't doubt our integrity, because our service tenet of Desheng is: we will not hesitate to undertake the problems that belong to us; we will try our best to help customers solve the problems that do not belong to us.

Biological buffer solution is a kind of solution which can keep pH value relatively stable when adding a small amount of acid or base. It is usually composed of weak acid and its conjugated base or weak base and its conjugated acid buffer pair. Most cells can only move in a narrow pH range, so a buffer system is needed to resist the pH change in the metabolic process. Buffer is widely used in biochemical field. How to distinguish the quality of buffer solution? What characteristics should they have?   Package drawing of biological buffer   First of all, let's take a closer look at what a buffer is?   Buffer is an aqueous solution containing conjugated acids or bases. The pH range of the buffer is determined by its pKa value. The pKa value is defined as the pH value when 50% of the molecules are acidic and 50% are basic. A conventional principle of buffer solution is that its pH value should be within the range of 1 pH value unit about pKa value, so as to ensure its good buffer capacity. In this way, it can be ensured that there are enough molecules in both acid and basic structure to neutralize them when H + or Oh - is added. In this way, the buffer can prevent the change of protein stability caused by pH change.   Good buffer must have the following characteristics:   1. Water solubility   2. Chemical stability   3. Good buffering capacity in the required pH range   4. It has good compatibility with analytical and experimental conditions   5. It has good compatibility with other solutes   Many substances can be used in biological buffers. The most commonly used buffer components usually have a near neutral pKa value and can be used around the physiological pH range. Table 1 lists the four most commonly used biological buffers, their respective pH ranges, and their advantages and disadvantages that may affect the protein purification process. To ensure adequate buffer capacity, the concentration of these buffers is usually 25mm.   The effect of buffer solution is as follows   The function of buffer solution is to adjust the pH value of the solution within a limited range, so that the acidity of the solution to be measured meets the range specified by the analytical method. For example, phenol can react with 4-aminoantipyrine in alkaline medium and the presence of potassium ferricyanide to produce orange red antipyrine dye. In order to prevent the interference of aromatic amines, the pH value of 10 ± 0.2 is the most suitable. Therefore, it is necessary to add ammonia money chloride buffer solution into the solution to be tested, and adjust and control the pH value of the solution to be measured to 10.0 ± 0.2.   Where can I buy a good buffer?   Desheng can provide high-quality buffer for customers. Desheng has been focusing on the R & D and production of biological buffer, blood collection additive and chemiluminescence reagent for 15 years, and can freely adjust the concentration of buffer required according to customer demand.   In practical work, some analysts do not understand the mechanism of buffer solution. When the buffer solution prepared and used is not in accordance with the specified value, in order to make the buffer solution meet the requirements, the strong acid and alkali such as hydrochloric acid or sodium hydroxide are used to adjust the buffer solution, thinking that this can make the buffer solution reach the required pH value as soon as possible. However, the results obtained are counterproductive Although the pH value of such a solution is adjusted correctly, its buffer system is destroyed and its function is lost. Generally, the buffer solution is a pair of conjugates composed of weak acid and its weak acid salt or weak base and its weak base salt.

The cold winter is the season of "everything is sleeping, but I grow meat", and the meat that grows is only fat, that is, fat. If these fats only increase, it will only be the next summer to show off. So how is the fat in the body metabolized? Let us understand how acetyl-CoA synthase and acetyl-CoA oxidase are involved in fat metabolism.   The full name of fat is triglyceride or triacylglyceride. It is a polyester composed of long-chain fatty acids and glycerol. It is a substance that can store a lot of energy in the body. When the carbohydrates in the body are not enough to provide energy, fat will begin to gradually break down to provide energy for the body. Fat itself is insoluble in water, so it has better stability. It is not easy to participate in the reaction or decomposition at room temperature. It can be gradually decomposed under the action of various enzymes in the body. Acetyl-CoA synthase and oxidase are involved in fat metabolism   Hydrolysis of fats into free fatty acids and glycerin The triglyceride (triglyceride) stored in the adipose tissue is gradually hydrolyzed by lipase into free fatty acid (FFA) and glycerol, which is released into the blood for the oxidation and utilization of various tissues throughout the body, which is called triacylglycerol mobilization. One molecule of fat is hydrolyzed by lipase into one molecule of glycerol and three molecules of fatty acid. Glycerol enters into sugar metabolism and oxidizes to release energy, or gluconeogenesis is converted into sugar or glycogen.   Acetyl-CoA synthase activated fatty acid The free fatty acids obtained from fat hydrolysis enter the cell fluid and are activated by acetyl-CoA synthase (ACS) in the presence of ATP, CoA-SH, and Mg into fatty acyl-CoA. Fatty acyl CoA contains high-energy thioester bonds, and its water solubility increases, which significantly increases the metabolic activity of fatty acyl groups.   Acetyl-CoA oxidase breaks down fat Fatty acid is activated into fatty acyl COA and then enters mitochondria. Acetyl-CoA oxidase (ACOD) and thiolase in the mitochondrial matrix can decompose long-chain fatty acyl COA through four steps of dehydrogenation, water addition, dehydrogenation and thiolysis. Continuous reaction, cleavage of fatty acyl group produces 1 molecule of acetyl CoA and 1 molecule of fatty acyl CoA with two carbon atoms less than the original. This is repeated until it is completely oxidized to acetyl CoA, which is finally oxidized to carbon dioxide and water.   Acetyl-CoA synthase and acetyl-CoA oxidase are also used in the field of biochemical testing. The enzyme preparations of these two enzymes from Desheng can be used in kits, fatty acid testing, glycerol testing, and triglyceride testing.

TRIS (77-86-1) is an important organic chemical raw material, and it is also a common biological buffer. Because of its wide buffering range and good buffering effect, in current research, TRIS has been continuously expanding its application. Now there are many labels such as biological buffers, surfactants, vulcanization accelerators, and pharmaceutical intermediates. With more and more applications, the procurement demand will inevitably increase. So for buyers, what are the criteria for choosing a high-quality TRIS manufacturer?     1. High raw material procurement standards   The production and development of any product is inseparable from the purchase of various raw materials. The quality of the raw materials is not high, so the quality of the products produced will be worrying. The same is true for tris. Recently, the raw materials for the production of tris TRIS have also seen a substantial price increase. For manufacturers, the proportion of raw material costs is relatively high, but Desheng will not because When the price of raw materials increases, buy low-priced, low-quality raw materials. Desheng always firmly believes that only by making good products can be recognized by customers. Desheng will review all raw material suppliers and also conduct corresponding inspections on raw materials. To ensure its reliable quality.   2. Strict assessment of staff   A high-quality TRIS (77-86-1) supplier In order to ensure the quality of each batch of products, not only will the staff responsible for the production be carefully trained, but also the staff will be very rigorously assessed to ensure every production The processes can be executed perfectly to effectively ensure the quality of the product. The production of the product is originally a delicate work, and mistakes will occur if you are not careful, so strict assessment is very necessary.     3. Have good storage and transportation conditions   The storage routines of chemical products have very strict requirements. They are stored according to different classifications. Tris TRIS is relatively easy to absorb moisture, so it should be stored in a sealed, dry place when storing. , Desheng’s current cardboard drums are packed with plastic inner bags, and the bottle mouths will be plastic sealed, so the tightness is very good. Coupled with the spacious warehouse for classified storage, TRIS has a good Storage conditions.   In general, as a high-quality TRIS base(77-86-1) supplier, Desheng currently has a large number of cooperative customers, and the praise continues, because Desheng will use high-quality raw materials to produce TRIS, and strictly assess the production personnel , There are good storage and transportation conditions, and Desheng is a direct manufacturer, there is more room for profit in the order quantity conference, welcome to buy!

When biochemical reactions are carried out, a constant pH value is usually required. A good biological buffer can keep the pH value constant and reach a stable working condition. In the process of cell culture, the growth and metabolism of cells will cause drastic changes in pH value of culture medium. In order to maintain the stable growth environment of cells, it is necessary to add appropriate amount of biological buffer in the culture medium.   Here is a brief introduction to how to maintain the pH value of biological buffer solution, because the buffer is composed of weak acid (HA) and its conjugated base (a –) or weak base and its conjugated acid. Weak acids and bases can not be completely dissociated in water, but exist in the equilibrium state of dissociated and non dissociated species in buffer solution.   For example, in acetic acid solution, there is an equilibrium of acetate ion, hydrogen ion and undivided acetic acid. Because of the dissociation of acetic acid (HAC), it can absorb H + or Oh -. HAC can release H + to neutralize Oh - and form water. Conjugated base a – can react with H + ions added to the system to produce acetic acid.   There are so many biological buffers and alternatives that can be used in cell culture on the market. Why choose HEPES? In fact, the suitable culture environment for most cells is ph7.2-ph7.4, while the application range of Desheng HEPES buffer just falls within ph6.8-ph8.2, which is in line with the characteristics of pH value needed for cell culture.   Compared with other buffers, HEPES has higher stability in maintaining the pH value of cell culture medium. Therefore, HEPES buffer is widely used in cell culture, tissue culture, protein purification and extraction, immunoprecipitation, cell division, living cell imaging and other biological and biochemical research.     Desheng is a professional biological buffer manufacturer with strong logistics capacity and rich export experience. We produce high-quality and high-purity HEPES buffer. We can provide a full range of product testing and special testing services according to your application needs.   In addition, we can also provide a variety of packaging specifications, HEPES purity ≥ 99%, good water solubility, stable process, can control the constant pH range for a long time. In any case, Desheng will be the best choice for you to buy HEPES!

Enzyme preparations are proteins with catalytic functions. They are biological preparations with special catalytic functions such as biochemical experiments and food processing. Nowadays, many users will search for keywords such as cost-effective enzyme preparation manufacturers on the Internet. The purpose of the search is to From the selection of more suitable products from these manufacturers, Desheng, as a professional manufacturer of enzyme preparations, will talk about what problems should be paid attention to when purchasing.     1. Choose enzyme manufacturers with diversified product types   Currently, cost-effective enzyme preparation manufacturers can provide users with a variety of different types of enzyme preparations for users to choose from, including single enzyme preparations and compound enzyme preparations. Because enzyme preparations can break down single nutrients, such as cellulase, amylase or pectinase, protease and lipase or phytase, and complex enzyme preparations are made by mixing two or more of one preparation. As a result, Desheng has dozens of enzyme preparation products, which can meet different use needs. This is one of the main reasons for the large amount of cooperation between enzyme preparation manufacturers.   2. Choose an enzyme preparation manufacturer with a guaranteed effect   Trustworthy enzyme preparation manufacturers will strictly abide by the corresponding procedures in the production process to ensure the use effect. If you don’t know how to check the effect, the best way is to refer to the standard of the authoritative company, as long as you use a unified standard to measure , You can make a comparison, and you can also ask the peers in the circle which manufacturer's products are more trustworthy. The effect of Desheng's enzyme preparation products is guaranteed. This is the biggest reason why most customers are willing to cooperate with them.   3. Understand the application of manufacturer's enzyme preparations Enzyme preparations are generally divided into several categories, including food and beverage enzymes, feed enzymes, etc., pharmaceutical enzymes and special enzymes (such as research and development reagents, etc.). The enzymes used in medicine have many types, low dosages, and high efficiency. Features: Desheng's enzyme preparation products are mainly used in biochemical testing and biochemical experiments. For example, glucose oxidase is mainly used to detect blood glucose concentration, cholesterol oxidase is widely used in clinical diagnosis of plasma total cholesterol content, and other experimental research. A variety of enzyme preparations are widely recognized at home and abroad.   In a word, the reason why Desheng's enzyme preparation products have such a large amount of cooperation is related to its ability to provide a rich variety of products, but also to the use effect of its products. You must pay attention to these aspects when choosing. Welcome customers with purchase needs to inquire and negotiate!

Heparin is common in clinical blood test with sodium salt and lithium salt, which has unique application value. Heparin has low chelating force, little influence on water molecule movement, less interference on blood components, no influence on red blood cell volume and no hemolysis. Therefore, heparin is recommended as anticoagulant in a variety of tests based on whole blood or plasma.   It is suitable for erythrocyte fragility test, blood gas analysis, hematocrit test, hemorheology and emergency biochemical determination. In the detection of pH value, blood gas, electrolyte and calcium ion, heparin is the only anticoagulant that can be used, and heparin lithium has the least possibility of interference in the detection of non lithium ions, so it is recommended to use heparin lithium as anticoagulant. At present, heparin lithium is gradually replacing heparin sodium in blood test. Heparin lithium is a chemical substance and an important member of blood anticoagulant. The appearance is white to nearly white powder with CAS No. 9045-22-1. The titers were divided into 150u, 160u, 170u and 180u. Heparin anticoagulants commonly used include sodium, potassium, lithium and ammonium salts of heparin, among which heparin lithium is the first.   Application of heparin lithium anticoagulant   1. Biochemical test for patients after hemodialysis: the blood sample of patients after hemodialysis is a special sample faced by the laboratory departments of many hospitals, and many inspectors often feel helpless when facing such samples. This is because hemodialysis patients use anticoagulant drugs containing heparin, such as low-molecular-weight heparin calcium, etc. in the process of hemodialysis, because there is a certain amount of heparin anticoagulant drugs in the blood, it is very difficult to coagulate and separate the bleeding clear after blood extraction in the common tube or separation gel / coagulant tube.   It has been reported that the detection of blood K with heparin lithium anticoagulant plasma and serum is biased, which may be caused by the high rotation speed of blood sample during centrifugation, the red blood cells in the blood clot of fibrin silk mesh are crushed, hemolytic, and the K ions in the red blood cells are released to the serum. In addition, a small amount of red blood cells will inevitably be destroyed during the transportation and coagulation of blood samples, resulting in slightly higher blood K.   It is also reported that there are significant differences in CK-MB, LDH, Glu between heparin lithium anticoagulant plasma and serum, which may be due to hemolysis or long storage time of blood glucose decomposition. On the contrary, heparin anticoagulant has the advantages of not affecting the cell volume and causing hemolysis easily. It does not need to be placed in a water bath and can be centrifuged directly. The blood K, Glu, LDH measured by heparin lithium anticoagulant plasma are more close to the real concentration of patients. Therefore, establishing the reference value system of plasma biochemical test as soon as possible is helpful for clinicians to make accurate judgment on patients' condition.   2. For routine biochemical tests: the results show that heparin lithium anticoagulant plasma can be used to replace serum in most routine biochemical test items, but the reference range of plasma should be established for Glu, K +, Na +, CI -, P3 -, and other items can be used to explain the results of plasma test with serum reference range; LP (a), PA, HBDH, LDH, CK, CKMB, IgM Plasma Lp (a) increased with the increase of heparin concentration.   Desheng has 19 years of rich experience in the development and production of blood anticoagulants. It is an old manufacturer of blood collection additives. The product has high purity of heparin lithium and heparin sodium, and the packaging can be made according to the needs of customers. Desheng biochemical insists on providing customers with high quality products and professional services.